Results 71 to 80 of about 791,804 (284)

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

Age-stratified anti-Müllerian hormone (AMH) nomogram: a comprehensive cohort study including 22.920 women

Frontiers in Endocrinology
BackgroundInfertility rates have been rising globally, necessitating accurate assessment tools for ovarian reserve. Anti-Müllerian hormone (AMH) is a key biomarker for evaluating ovarian reserve, yet age-stratified reference data remain limited ...
Kiper Aslan, Isil Kasapoglu, Bahadir Kosan, Aylin Tunali, Ilayda Tellioglu, Gurkan Uncu   +5 more
doaj   +1 more source

Comparative study of assisted reproductive outcomes between young patients with occult premature ovarian insufficiency and advanced-age patients

Journal of International Medical Research, 2020
Objective The purpose of this study was to compare the pregnancy outcomes among young patients with occult premature ovarian insufficiency (OPOI), advanced-age patients with diminished ovarian reserve (DOR), and advanced-age patients with normal ovarian ...
Ling-nv Yao, Wen-qin Lin, Nan Jiang, Chuyan Li, Hai-feng Cao, Hong Li, Jian-hua Qian   +6 more
doaj   +1 more source

In vitrofertilization outcomes in women with surgery induced diminished ovarian reserve after endometrioma operation: Comparison with diminished ovarian reserve without ovarian surgery

Obstetrics & Gynecology Science, 2017
To compare the in vitro fertilization (IVF) outcomes between women with diminished ovarian reserve (DOR) after endometrioma operation and women with DOR without ovarian surgery.This retrospective case-control study included 124 women aged under 40 and had DOR (serum anti-Müllerian hormone level
Su Been Hong, Na Ra Lee, Seul Ki Kim, Hoon Kim, Byung Chul Jee, Chang Suk Suh, Seok Hyun Kim, Young Min Choi   +7 more
openaire   +2 more sources

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Efficacy of Acupuncture for Diminished Ovarian Reserve: A Randomized Controlled Trial Protocol [PDF]

Yuemeng Zhao,1,2,* Liying Liu,1,* Xinyue Tao,1,* Di Gan,1,3 Yuanyuan Lai,1 Chunhui Tian,1 Lei Huang,1 Yufei Huang,1 Jie Yang1 1College of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province ...
Lai Y, Yang J, Liu L, Huang Y, Tao X, Tian C, Huang L, Zhao Y, Gan D   +8 more
core  

Is there any relationship between cardiovascular risk markers and young women with diminished ovarian reserve?

, 2014
Objective: It has been widely known that cardiovascular disease (CVD) risk is increased in menopause. The aim of the study was to evaluate whether this risk was elevated in young women with diminished ovarian reserve (DOR)
Omer, Beyhan, SAKAR, Nafi, Keskin, Seda, YALCINKAYA, Sener, VERIT, Fatma Ferda   +4 more
core   +1 more source

Identification of a unique epigenetic profile in women with diminished ovarian reserve

, 2021
Objective: To investigate whether epigenetic profiles of mural granulosa cells (MGC) and leukocytes from women with diminished ovarian reserve (DOR) differ from those of women with normal or high ovarian reserve.
Perry, John R.B., Chan, Andrew Cho, Hoffmann, Eva R., Bungum, Mona, Zedeler, Anne, Kelsey, Gavin, Castillo-Fernandez, Juan, la Cour Freiesleben, Nina, Cardona, Alexia, Grøndahl, Marie Louise, Olsen, Kristina W., Skouby, Sven O., Juan Castillo-Fernandez, Andrew Cho Chan, Mona Bungum, Gavin Kelsey, John R.B. Perry, Sven O. Skouby, Eva R. Hoffmann, Marie Louise Grøndahl, Nina la Cour Freiesleben, Alexia Cardona, Kristina W. Olsen, Anne Zedeler   +23 more
core   +1 more source

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

Diminished Ovarian Reserve is Not Associated With Luteal Phase Deficiency in Women of Older Reproductive Age [PDF]

, 2018
Objective: To determine the association between biomarkers of ovarian reserve and luteal phase deficiency.Methods: This is a secondary analysis of data from a prospective time-to-conceive cohort study performed at the University of North Carolina.
Pfister, Abbey
core   +1 more source