Results 81 to 90 of about 9,464 (283)

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

Empty Follicle Syndrome: The Possible Cause of Occurrence

Oman Medical Journal, 2015
Objectives: Empty follicle syndrome (EFS), although rare, is a disappointing condition in which no oocytes are retrieved from mature follicle after ovulation induction in in vitro fertilization (IVF) cycles.
Tahereh Madani, Nadia Jahangiri
doaj   +1 more source

External validation of anti-Müllerian hormone based prediction of live birth in assisted conception [PDF]

, 2013
<p>Background - Chronological age and oocyte yield are independent determinants of live birth in assisted conception. Anti-Müllerian hormone (AMH) is strongly associated with oocyte yield after controlled ovarian stimulation.
Grisendi, V., Lloyd, S.M., McConnachie, A., Fleming, R., Khader, A., La Marca, A., Nelson, S.M.   +6 more
core   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Genotypes and alleles frequencies distribution in diminished and normal ovarian reserve groups.

, 2015
* In these groups, the population must necessarily have the two inclusion criteria (AMH and AFC).Genotypes and alleles frequencies distribution in diminished and normal ovarian reserve groups.
Adriana Renzi (707412), Claudia Guilhermino Petersen (707415), Mario Cavagna (707419), João Batista Alcantara Oliveira (707417), Gabriela Ravanelli Oliveira-Pelegrin (707413), José Gonçalves Franco Junior (707420), Maria do Carmo Tomitão Canas (707414), Ana Lucia Mauri (707416), Ricardo Luiz Razera Baruffi (707418), Laura Diniz Vagnini (707411)   +9 more
core   +1 more source

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

Ovarian reserve

, 2005
The tendency to delay childbirth has increased the importance of ovarian reserve as a determinant of infertility treatment outcome. In the context of assisted reproduction technology, effective strategies to overcome the impact of ovarian aging and ...
Fauser, BCJM, Macklon, NS
core   +1 more source

Modified letrozole vs GnRH antagonist protocols in ovarian aging women for IVF: an open-label, multicenter, randomized controlled trial

Nature Communications
For women with diminished ovarian reserve or of advanced age, controlled ovarian stimulation presents a significant challenge during in vitro fertilization cycles.
Yang Zhao, Shuyun Zhao, Jiawen Xu, Jingbo Chen, Yun Lin, Yuhong Peng, Xuemei Li, Ping Pan, Jing Shu, Xiaojia Li, Jie Wang, Chu Chu, Rui Hu, Yiqi Yu, Yunting Zhang, Saif ur Rehman, Guanghui Dong, Dongzi Yang, Ricardo Azziz, Ben W. Mol, Yankai Xia, Xiaomiao Zhao   +21 more
doaj   +1 more source

Is there any relationship between cardiovascular risk markers and young women with diminished ovarian reserve?

, 2014
Objective: It has been widely known that cardiovascular disease (CVD) risk is increased in menopause. The aim of the study was to evaluate whether this risk was elevated in young women with diminished ovarian reserve (DOR)
Omer, Beyhan, SAKAR, Nafi, Keskin, Seda, YALCINKAYA, Sener, VERIT, Fatma Ferda   +4 more
core   +1 more source

CCT2 Promotes Prostate Cancer Progression Through EIF3F‐Dependent Stabilization of FASN

Advanced Science, EarlyView.
ABSTRACT Prostate cancer (PCa) is increasingly recognized to be driven by dysregulated lipid metabolism. Although fatty acid synthase (FASN) is highly expressed in PCa, the mechanisms governing FASN protein stability and its functional integration into oncogenic lipid metabolism remain poorly defined.
Shun Xu, Yifan Zhang, Haolin Li, Shengyu Zhao, Xiaoran Dai, Qili Xu, Mintian Fei, Chun Li, Zhihui Zou, Baojun Wang, Li Zhang, Hui Wang, Ligang Zhang, Chaozhao Liang   +13 more
wiley   +1 more source