Biological Roles Played by Sphingolipids in Dimorphic and Filamentous Fungi. [PDF]
MBio, 2018 Filamentous and dimorphic fungi cause invasive mycoses associated with high mortality rates. Among the fungal determinants involved in the establishment of infection, glycosphingolipids (GSLs) have gained increased interest in the last few decades.
Maurizio Del Poeta +2 more
exaly +8 more sources
Caenorhabditis elegans as an Infection Model for Pathogenic Mold and Dimorphic Fungi: Applications and Challenges [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 The threat burden from pathogenic fungi is universal and increasing with alarming high mortality and morbidity rates from invasive fungal infections. Understanding the virulence factors of these fungi, screening effective antifungal agents and exploring ...
Chukwuemeka Samson Ahamefule +1 more
exaly +5 more sources
Diagnosis of Human Endemic Mycoses Caused by Thermally Dimorphic Fungi: From Classical to Molecular Methods [PDF]
Journal of FungiHuman endemic mycoses are potentially fatal diseases caused by a diverse group of fungi that can alter their morphology in response to an increase in temperature.
Joaquina María García-Martín +2 more
doaj +4 more sources
The Ecology of Non-Candida Yeasts and Dimorphic Fungi in Cetaceans: From Pathogenicity to Environmental and Global Health Implications. [PDF]
J Fungi (Basel)Cetaceans, which are integral to marine ecosystems, face escalating anthropogenic threats, including climate change and pollution, positioning them as critical sentinel species for ocean and human health.
Garcia-Bustos V +5 more
europepmc +4 more sources
Genome analysis reveals evolutionary mechanisms of adaptation in systemic dimorphic fungi. [PDF]
Sci Rep, 2018 Dimorphic fungal pathogens cause a significant human disease burden and unlike most fungal pathogens affect immunocompetent hosts. To examine the origin of virulence of these fungal pathogens, we compared genomes of classic systemic, opportunistic, and ...
Muñoz JF, McEwen JG, Clay OK, Cuomo CA.
europepmc +3 more sources
Gene Editing in Dimorphic Fungi Using CRISPR/Cas9. [PDF]
Curr Protoc Microbiol, 2020 Dimorphic fungi in the genera Blastomyces, Histoplasma, Coccidioides, and Paracoccidioides are important human pathogens that affect human health in many countries throughout the world.
Kujoth GC, Sullivan TD, Klein BS.
europepmc +5 more sources
Co-infection by dimorphic fungi in tuberculosis patients in Kenya
International Journal of Mycobacteriology, 2020 Background: Dimorphic fungi may cause infections and symptoms similar to tuberculosis (TB), in humans and animals. Such infections, individually or concurrently with TB, have been identified in cattle in Kenya, raising the possibility of infections in ...
Joseph K Ngei. Kuria +2 more
doaj +4 more sources
Antifungal Resistance, Metabolic Routes as Drug Targets, and New Antifungal Agents: An Overview about Endemic Dimorphic Fungi. [PDF]
Mediators Inflamm, 2017 Diseases caused by fungi can occur in healthy people, but immunocompromised patients are the major risk group for invasive fungal infections. Cases of fungal resistance and the difficulty of treatment make fungal infections a public health problem.
Parente-Rocha JA +6 more
europepmc +2 more sources
Terpinen-4-ol, tyrosol, and β-lapachone as potential antifungals against dimorphic fungi. [PDF]
Braz J Microbiol, 2016 This study aimed to evaluate the in vitro antifungal activity of terpinen-4-ol, tyrosol, and β-lapachone against strains of Coccidioides posadasii in filamentous phase (n = 22) and Histoplasma capsulatum in both filamentous (n = 40) and yeast phases (n =
Brilhante RS +14 more
europepmc +2 more sources
Hybrid histidine kinases and antifungal warfare in thermal dimorphic fungi [PDF]
Antimicrobial Agents and ChemotherapyThermal dimorphic fungal pathogens are fungi that infect humans, often through the inhalation of asexual conidia, and which transition from hyphae to yeast in the human body.
Frances S. Faguy +2 more
doaj +2 more sources