Results 71 to 80 of about 1,419 (162)
Signaling Pathways Regulating Dimorphism in Medically Relevant Fungal Species
Pathogenic fungi that exhibit the ability to alternate between hyphal and yeast morphology in response to environmental stimuli are considered dimorphic. Under saprobic conditions, some fungi exist as filamentous hyphae, producing conidia.
Uriel Ramírez-Sotelo +2 more
doaj +1 more source
NADPH dehydrogenase gene deletion significantly triggered NADPH/NADP+ increase in mutant strains. NADPH gene deletion promoted Fatty acid biosynthesis and repressed β‐oxidation. NADPH gene deletion decreased oxidative phosphorylation and increased substrate‐level phosphorylation. Mutants exhibited hypersensitivity to oxidative stress, but promoted more
Yanling Qiu +6 more
wiley +1 more source
Shaping future forests: how can ecophysiology support climate‐smart forest management?
Summary Climate change, particularly the associated increase in extreme events and disturbances, threatens the numerous environmental, social, and economic benefits that forests provide, both locally and globally. Heat and drought pose significant risks to forest ecosystems; the anticipated future climate is expected to exacerbate this trend ...
Arthur Gessler +18 more
wiley +1 more source
Genome analysis reveals evolutionary mechanisms of adaptation in systemic dimorphic fungi
Dimorphic fungal pathogens cause a significant human disease burden and unlike most fungal pathogens affect immunocompetent hosts. To examine the origin of virulence of these fungal pathogens, we compared genomes of classic systemic, opportunistic, and ...
Juan G. McEwen +3 more
core +1 more source
Ammonium Signalling in Dimorphic Fungi [PDF]
Ph. D. ThesisAmmonium is a preferred source of nitrogen utilised by fungi. In some fungi ammonium availability is sensed by ammonium transporters belonging to the Amt/Mep/Rh superfamily. During ammonium limiting conditions these transporters trigger a
Lister, Siobhan Hope
core
Silene, a versatile model system: from sex and genome evolution to ecology and speciation
Summary Fundamental and applied research in evolutionary biology benefits from the use of model systems in which approaches from disparate disciplines can be integrated. Here, we review recent progress in evolutionary research on the long‐standing model system Silene, a large genus with a well‐resolved phylogeny and newly available, expanded genomic ...
Sophie Karrenberg +16 more
wiley +1 more source
Update of the risk assessment on dioxins and dioxin‐like PCBs in feed and food
Abstract The European Commission asked EFSA to update its 2018 risk assessment on polychlorinated dibenzo‐p‐dioxins and dibenzofurans (PCDD/Fs) and dioxin‐like polychlorinated biphenyls (DL‐PCBs) in feed and food, based on the 2022 WHO Toxic Equivalency Factors (WHO2022‐TEFs).
EFSA Panel on Contaminants in the Food Chain (CONTAM Panel) +27 more
wiley +1 more source
Cetaceans, which are integral to marine ecosystems, face escalating anthropogenic threats, including climate change and pollution, positioning them as critical sentinel species for ocean and human health. This review explores the neglected realm of non-
Acosta Hernández, Begoña María +5 more
core +1 more source
Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley +1 more source
The regulation of the cAMP signalling pathway in the human pathogenic fungus Paracoccidioides brasiliensis [PDF]
Paracoccidioides brasiliensis (Pb) is the causative agent of the disease Paracoccioidomycosis (PCM), which is one of the most prevalent systemic mycoses in Latin Amercia (Borges-Walmsley et al., 2002). P.
Janganan, Thamarai kannan
core

