Results 81 to 90 of about 749,082 (227)

Genome analysis reveals evolutionary mechanisms of adaptation in systemic dimorphic fungi

, 2017
Dimorphic fungal pathogens cause a significant human disease burden and unlike most fungal pathogens affect immunocompetent hosts. To examine the origin of virulence of these fungal pathogens, we compared genomes of classic systemic, opportunistic, and ...
Juan G. McEwen, Oliver K. Clay, Christina A. Cuomo, José F. Muñoz   +3 more
core   +1 more source

Nikkomycin Z—Ready to Meet the Promise?

Journal of Fungi, 2020
Nikkomycin Z (NikZ) has fungicidal activity against some fungal species which currently requires patients to endure chronic therapy, sometimes for years.
David J. Larwood
doaj   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, Volume 2, Issue 3, September 2026.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

A new hypothetical cell wall model for the dimorphic pathogenic fungi S. schenckii and S. brasiliensis.

, 2018
This model is based on biochemical and structural analyses (IR, 1H-NMR and 13C-NMR spectroscopy) as well as HPF-TEM and fluorescence microscopy with ConA-Texas Red, WGA-FITC and CFW, which indicated the presence of a peptido-rhamnomannan component ...
Laura Barreto (4925797), Karina Garcia (4925791), Bernardo Franco (4925794), Gustavo Niño-Vega (4925788), José A. Martínez-Álvarez (4925800), Gabriela W. P. Neves (171508), Carol A. Munro (43878), Neil A. R. Gow (43882), Louise A. Walker (43877), Hector Villalobos-Duno (4925803), Héctor M. Mora-Montes (4925806), Leila M. Lopes-Bezerra (467714)   +11 more
core   +1 more source

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits [PDF]

, 2002
We tested the hypothesis that genes encoded on the sex chromosomes play a direct role in sexual differentiation of brain and behavior. We used mice in which the testis-determining gene (Sry) was moved from the Y chromosome to an autosome (by deletion of ...
Robin Lovell-Badge, De Vries, Geert, Auger, CJ, Lovell-Badge, R, Catherine J. Auger, Elka M. Scordalakes, Swain, A, Simerly, Richard B., Lovell-Badge, Robin, Richard B. Simerly, Amanda Swain, Arnold, Arthur P., Simerly, RB, Burgoyne, PS, Scordalakes, Elka M., Emilie F. Rissman, Geert J. De Vries, Liang-Yo Yang, Burgoyne, Paul S., Yang, Liang-Yo, Yang, L-Y, Rissman, EF, Rissman, Emilie F., Paul S. Burgoyne, De Vries, G, Arnold, AP, Arthur P. Arnold, Scordalakes, EM, Swain, Amanda, Auger, Catherine J.   +29 more
core   +1 more source

Signaling Pathways Regulating Dimorphism in Medically Relevant Fungal Species

Pathogens
Pathogenic fungi that exhibit the ability to alternate between hyphal and yeast morphology in response to environmental stimuli are considered dimorphic. Under saprobic conditions, some fungi exist as filamentous hyphae, producing conidia.
Uriel Ramírez-Sotelo, Manuela Gómez-Gaviria, Héctor M. Mora-Montes   +2 more
doaj   +1 more source

Protoplasting and Transformation Using CRISPR/Cas9 in Coccidioides

Current Protocols, Volume 6, Issue 9, September 2026.
Abstract Coccidioides posadasii and C. immitis are human fungal pathogens endemic to the American Southwest. C. posadasii and C. immitis are the causative agents of coccidioidomycosis, or Valley fever. They are pathogens of growing concern, as reported cases of coccidioidomycosis have increased 20‐fold in the last two decades.
Katrina M. Jackson, Matthew M. Morales, Edyta Szewczyk, Christina M. Homer, Ashley N. Itogawa, Rachel B. Brem, Anita Sil, Bridget M. Barker   +7 more
wiley   +1 more source

Endobronchial Aspergillosis Presenting as an Isolated Airway Lesion in an Immunocompromised Patient

Respirology Case Reports, Volume 14, Issue 9, September 2026.
Endobronchial Aspergillus infection should be considered in immunocompromised patients presenting with airway obstruction, even in the absence of parenchymal lung involvement. This case highlights the potential for rapid clinical deterioration and the diagnostic challenges in distinguishing endobronchial aspergillosis from more aggressive forms of ...
Mohsen Sadeghi, Fatemeh Sadat Hosseini Khajouei, Haniyeh GhanbarAliAkhavan, Amir Morteza Soleimani   +3 more
wiley   +1 more source

Clinically Important Emerging and Uncommon Fungal Pathogens in Asia: Epidemiology, Antifungal Resistance and Challenges in Diagnosis and Management

Mycoses, Volume 69, Issue 9, September 2026.
ABSTRACT Fungal infections in Asia are influenced by warm, humid climates, high population density and expanding healthcare systems, which together facilitate the emergence, transmission and detection of both common and rare pathogens. While Candida and Aspergillus species remain the leading causes of invasive fungal disease, increasing attention has ...
Narut Chancharussin, Anupop Jitmuang, Arunaloke Chakrabarti, Methee Chayakulkeeree   +3 more
wiley   +1 more source

Isolation of Nucleic Acids from Filamentous Fungi

, 2010
Based on morphological criteria, fungi are often separated into two groups: yeasts and filamentous fungi. Uncellular fungi are known as yeasts. The extraction of nucleic acids from yeasts cells is described in Chapter 9.
Cheetham, Brian F, Katz, Margaret E
core