Results 31 to 40 of about 613 (86)
Journal of the American Geriatrics Society, Volume 74, Issue 3, Page 854-867, March 2026.ABSTRACT Introduction Although frailty is considered a potentially modifiable risk factor for dementia, its influence on health outcomes in individuals with established dementia remains unclear. This study aims to systematize the current evidence to understand the impact of frailty on the development of adverse outcomes in older adults with dementia ...
Miguel German Borda +11 more
wiley +1 more source
Uluslararası Literatürde Bağımlılık ve Maneviyat Araştırmalarının Bibliyometrik Analizi
Dini AraştırmalarBağımlılık ve maneviyat araştırmaları, birey ve toplum açısından kritik öneme sahip alanları temsil etmektedir. Farklı disiplinlerde yürütülen bağımlılık ve maneviyat araştırmaları mevcut durumun anlaşılmasını zorlaştırmaktadır. Uluslararası literatürde “
Soner Ercan
doaj +1 more source
Annals of Clinical and Translational Neurology, Volume 13, Issue 2, Page 354-366, February 2026.ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu +9 more
wiley +1 more source
Soluble SORL1 in cerebrospinal fluid as a marker for functional impact of rare SORL1 variants
Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.Abstract INTRODUCTION The sortilin‐related receptor (SORL1) directs APP and Aβ trafficking within the retromer pathway. Cleavage at the cell surface releases soluble SORL1 (sSORL1) into cerebrospinal fluid (CSF). We examined whether CSF‐sSORL1 can serve as an in vivo marker of genetically impaired SORL1.
Matthijs W. J. de Waal +24 more
wiley +1 more source
GENÇ YETİŞKİNLERİN DİN VE DİNDARLIK ANLAYIŞLARI ÜZERİNE NİTEL BİR ARAŞTIRMA
Kilis 7 Aralık Üniversitesi İlahiyat Fakültesi DergisiHızlı toplumsal değişmeler dünya görüşlerini, değer yargılarını dönüşüme uğratmaktadır. Din anlayışları da bu sürece tabidir. Saha araştırmaları Batılı son nesilde öncekilere oranla dinsiz, ateist ve spirütüelci eğilimlerin arttığına dair bulgular ...
Ahmet Aslan
doaj +1 more source
Glia, Volume 74, Issue 1, January 2026.C9orf72 microglia display heightened glycolysis and oxidative stress, driving astrocytic reprogramming that impacts motor neurons. iPSC tricultures uncover key glial–neuronal interactions in C9orf72 pathology. ABSTRACT The C9orf72 hexanucleotide repeat expansion mutation is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and ...
Marika Mearelli +12 more
wiley +1 more source
Cumhuriyet Üniversitesi İlahiyat Fakültesi Dergisi, 2002 Her bilim dalının gelişim süreci olduğu gibi yaşlılık dönemiyle ilgili araştırmaları konu alan gerontolojinin de başlangıcından. günümüze kadar kronolojik anlamda tarihsel bir birikim süreci vardır.
Mustafa KOÇ
doaj
Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.Abstract INTRODUCTION Currently, our ability to predict cognitive decline in Parkinson's disease is limited. METHODS In 234 dementia‐free PD patients, cognitive profiles at baseline were determined using cluster analysis and longitudinal associations with global cognitive z‐score, health‐related quality of life (HR‐QoL), caregiver burden, and risk of ...
Saira S. Mirza +14 more
wiley +1 more source
Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.Abstract INTRODUCTION Pretangle tau inclusions from the locus coeruleus (LC) are hypothesized to propagate to the entorhinal cortex (EC) via neuron‐to‐neuron transmission along its projections. The lower integrity of the LC‐EC pathway accompanying Alzheimer's disease (AD) pathology is supported by post mortem studies, but in vivo evidence remains ...
Yuliya Patsyuk +10 more
wiley +1 more source
Detection of TDP‐43 seeds in CSF of presymptomatic and symptomatic genetic FTD/ALS
Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.Abstract INTRODUCTION Seed amplification assays (SAAs) have shown promising results in detecting misfolded transactive response (TAR) DNA‐binding protein 43 (TDP‐43) in cerebrospinal fluid (CSF) of genetic frontotemporal dementia (FTD). To date, the use of SAA has yet to be evaluated in presymptomatic individuals.
Ilaria Linda Dellarole +20 more
wiley +1 more source