Results 21 to 30 of about 301,649 (230)

Metin Yasa, Şiirlerle Din Felsefesi; İman-Akıl-Aşk (Ankara: Elis Yayınları, 2019)

open access: yesMilel ve Nihal, 2023
Metin Yasa tarafından kaleme alınan bu eser; “Önsöz”, “Giriş”, “Din Felsefesi”, “Tanrı’nın Varlığı”, “Din Dili ve Tanrı’yı Konuşma”, “Kötülük Sorunu”, “Ölümsüzlük Sorunu”, “Tanrı-evren İlişkisi”, “Din, Bilim, Felsefe ve Etik ...
Fadime Rukiye Bayındır
doaj   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

open access: yesHepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli   +13 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Chibisuke27/Supporting-Information-for-DDI-MLP-DILI-c-MLP-and-DILI-s-MLP: Supporting Information for DILI MLP, DILI-c MLP and DILI-s MLP

open access: yes, 2020
This is the first release of the Supporting Information for DILI MLP, DILI-c MLP and DILI-s ...
Chibisuke27
core   +1 more source

Molla Sadrâ’da Allah’ı Bilmenin İmkânı ve O’nun Hakkında Konuşmanın Sınırları

open access: yesHitit İlahiyat Dergisi, 2021
Bu makalenin temel amacı, Allah’ı bilmenin imkânı ve O’nun hakkında konuşmanın sınırlarını dile getirmeye çalışan alternatif bir yaklaşımı ortaya koymaktır.
Hüsnü Aydeniz
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Din ve Hayat Dergisi: Ev

open access: yes, 2021
Din ve Hayat Dergisi'nin Ev konulu ...

core   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

open access: yesAdvanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen   +15 more
wiley   +1 more source

anikaliu/CAMDA-DILI: CAMDA-DILI

open access: yes, 2021
Repository linked to the following manuscript: Liu, A., Walter, M., Wright, P. et al. Prediction and mechanistic analysis of drug-induced liver injury (DILI) based on chemical structure. Biol Direct 16, 6 (2021). https://doi.org/10.1186/s13062-020-00285-
Abdurrahman Elbasir   +3 more
core   +1 more source

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