Results 61 to 70 of about 268 (186)
Din Sosyolojisinin Yöntemsel İncelikleri: Bir Şematikleştirme Çabası
Din sosyolojisi, bulunduğu kategori itibarıyla sosyoloji ile dini araştırmaların kesişiminde interdisipliner bir oluşum göstermektedir. Asal parametrelerden biri olarak dinin, diğer değişkenlerle ilişkisi açıklanmaya ve mevcut örüntü çözümlenmeye ...
Birsen Banu Okutan
doaj +1 more source
The NLRP3 Inflammasome: Mechanisms of Activation, Regulation, and Therapeutic Opportunities
Diverse diseases converge on NLRP3. We depict a discovery‐to‐clinic track: high‐throughput/phenotypic screens, structure‐guided design, and modality innovation (allosteric inhibitors, interface blockers, degraders) deliver third‐generation, disease‐tailored NLRP3 control.
Chan Zou +5 more
wiley +1 more source
Risk Assessment for Drug‐Induced Hyperbilirubinemia: A Mechanistic Approach
ABSTRACT Hyperbilirubinemia, characterized by elevated total blood bilirubin levels including both unconjugated and conjugated forms, serves as a diagnostic marker for drug‐induced liver toxicity associated with a wide range of medications. This study aimed to develop a mechanistic model for assessing hyperbilirubinemia risk using genetic markers.
Rajeev Kumar +4 more
wiley +1 more source
ARAP DİLİ VE DİN DİLİ İÇERİSİNDE 'İKRA' ('OKU!') KAVRAMININ YERİ
ÖZET Bu çalışmada, Arap Dili ve Edebiyatı ve Din Dili içerisindeki 'Oku' kavramının yeri incelenmeye gayret edilmiştir. Ayrıca bu kavramın deskriptif ve linguistik tahlilleri üzerinde durulmuş, okumanın amacı, gerçek bir okuyucu olmanın kriterleri, okumanın hastalıkları ve zararları, Tanrı sözleri olan Kur'ân'ın nasıl okunması gerektiği gibi konulara ...
openaire +1 more source
Open Systems Pharmacology Community Conference (OSP‐CC) Proceedings 2025
ABSTRACT Developed at Bayer Technology Services, PK‐Sim and MoBi transitioned into the Open Systems Pharmacology (OSP) Suite, released as free open‐source software in 2017. An active community with stakeholders from academia, industries, and regulators contributes to the continuous improvement of open‐source model‐informed drug development (MIDD). This
Henrik Cordes +35 more
wiley +1 more source
Atorvastatin‐Associated Liver Injury: Outcome After Statin Rechallenge
ABSTRACT Background Statin‐induced liver injury is frequent and usually not severe. The aim of the present study was to describe the safety of statin rechallenge after atorvastatin‐induced liver injury because it is poorly documented. Methods Cases of liver injury involving atorvastatin were selected from the French pharmacovigilance database ...
Blandine Bertin +5 more
wiley +1 more source
Machine learning liver-injuring drug interactions with non-steroidal anti-inflammatory drugs (NSAIDs) from a retrospective electronic health record (EHR) cohort. [PDF]
Datta A +5 more
europepmc +1 more source
Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases
Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li +3 more
wiley +1 more source
İnsan, manevi dünyası olan, düşünen ve inanan bir varlıktır. İnsanın manevi dünyasında tezahür eden inanç ve düşünceler; güzellik, estetik ve sanat gibi olgularla birlikte kültürel algısının oluşmasında etkin olmuştur.
Mehmet Gönül, Onur Altıntuğ
doaj

