Results 21 to 30 of about 1,009 (89)

Endocrine Disruptive Effects of the Herbicides Linuron, Chloridazon and Metribuzin on Bovine Granulosa Cells

Reproduction in Domestic Animals, Volume 61, Issue 4, April 2026.
ABSTRACT Linuron, chloridazon and metribuzin are herbicides thought to have potential endocrine disruption (ED) effects. This study investigated the effects of linuron, chloridazon and metribuzin on bovine granulosa cell viability and oestrogen (E2) and progesterone (P4) secretion in vitro.
Metehan Eser Kahveci, Ayse Arzu Yigit, Ruhi Kabakci   +2 more
wiley   +1 more source

Glycative Stress Disrupts the Mitochondrial‐Lysosome Axis and Promotes Geroconversion in Aging Cardiomyocytes

Aging Cell, Volume 25, Issue 3, March 2026.
Cardiac aging promotes mitochondrial AGE accumulation driven by defective glycative stress detoxification. AGE‐modified mitochondria disrupt lysosomal proteolysis, impairing mitophagy and promoting lipofuscin buildup. This mechanism sustains chronic unresolved mitochondrial damage, driving proinflammatory senescence in cardiomyocytes and defining a ...
Diana Bou‐Teen, Simonas Valiuska, Elisabet Miro‐Casas, Chiara Rubeo, Elena Bonzon‐Kulichenko, Zuzana Nichtova, Celia Fernandez‐Sanz, Javier Inserte, Antonio Rodriguez‐Sinovas, Begoña Benito, Eduard Ródenas‐Alesina, Jesús Vázquez, Ignacio Ferreira‐González, Marisol Ruiz‐Meana   +13 more
wiley   +1 more source

Toward Imaging Biosensors for Spatial Mapping of Analytes in Macroscopic Specimens

Advanced Sensor Research, Volume 5, Issue 2, February 2026.
This perspective provides an overview of imaging biosensors used for spatial mapping of analytes on the surfaces of macroscopic specimens, such as plant and animal tissues. These devices incorporate various detection principles, including colorimetry, fluorometry, bioluminescence, ultrasound‐assisted, electrochemical, and thermometric detection.
Hayelom Dargo Beyene, Pawel L. Urban
wiley   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, Volume 16, Issue 1, Page 199-221, January 2026.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy

Advanced Science, Volume 13, Issue 1, 5 January 2026.
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li, Fulong Man, Jianwei Cheng, Li Chen, Yongyong Li, Haiqing Dong   +5 more
wiley   +1 more source

Photocatalytic Reduction of Nitroaromatic Compounds Using NiO‐Modified MgAl Hydrotalcite: A Sustainable Approach for Wastewater Treatment

Journal of Chemistry, Volume 2026, Issue 1, 2026.
The growing industrialization has caused the generation of highly toxic compounds such as nitroaromatic compounds. An adequate treatment to reduce the contamination of these organic compounds is necessary. The photocatalytic reduction of aromatic compounds using semiconductor materials favors the production of nitroaromatics.
Leimmy Calderon, Daniela Barrera, Claudia Castañeda, Jose J. Martínez, Hugo Rojas, Francisco Tzompanzi, Dora Solis, Sonia Mancipe Estevez, Munmun Bardhan   +8 more
wiley   +1 more source

FUNDC1‐Associated Regulation of Mitochondrial Function Is Crucial for Preventing Endothelial Injury in Hyperglycemia

Oxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.
Mitochondria are intracellular organelles that regulate cell survival and death. Hyperglycemia modulates the functioning of the mitochondria in endothelial cells. We discovered that high‐glucose (HG) treatment reduces FUN14 domain‐containing 1 (FUNDC1) expression in endothelial cells.
Vinothkumar Rethineswaran, Young Joon Hong, Woong Bi Jang, Jaewoo Choi, Hye Ji Lim, Sangmi Park, Eun Ji Lee, Jong Seong Ha, Jisoo Yun, Sang-Mo Kwon, Enrico Desideri   +10 more
wiley   +1 more source

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

Advanced Science, Volume 12, Issue 48, December 29, 2025.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu, Leyi Wang, Tao Lv, Chen Jin, Qiong Wu, Yongjie Zhou, Gang Xu, Zhenyu Duan, Kui Luo, Jiayin Yang   +9 more
wiley   +1 more source

Anoxygenic phototrophic purple non-sulfur bacteria: tool for bioremediation of hazardous environmental pollutants. [PDF]

World J Microbiol Biotechnol, 2023
Dhar K, Venkateswarlu K, Megharaj M.
europepmc   +1 more source

Fitness costs of resistance to insecticides in insects. [PDF]

Front Physiol, 2023
Gul H, Gadratagi BG, Güncan A, Tyagi S, Ullah F, Desneux N, Liu X.   +6 more
europepmc   +1 more source