Results 21 to 30 of about 1,518 (175)

Would you use it with a seal of approval? Important attributes of 2,4-dinitrophenol (2,4-DNP) as a hypothetical pharmaceutical product [PDF]

open access: yes, 2018
Background2,4-Dinitrophenol (2,4-DNP) is an effective but highly dangerous fat burner, not licensed for human consumption. Death cases reported for 2,4-DNP overdose, particularly among young adults, have raised concerns about the ineffective regulatory ...
Ainsworth   +74 more
core   +3 more sources

Inhibition of adenosine triphosphatase and respiration of rat-liver mitochondria by dinitrophenols [PDF]

open access: yes, 1964
1. The stimulating and inhibitory effect of nitrophenols on various mitochondrial systems are compared. Both respiration and ATPase are stimulated by low dinitrophenol concentrations followed by inhibition at higher concentrations.
Hemker, H.C.
core   +2 more sources

Docetaxel‐Induced Immune Activation Shows Antitumor Synergy With the Tumor‐Targeted CD40 Agonist KK2269

open access: yesCancer Science, EarlyView.
CD40 agonists have demonstrated proof‐of‐concept for converting an immunologically cold tumor into a hot tumor in preclinical studies; however, clinically, they have shown limited antitumor efficacy as monotherapy. We tested a tumor‐targeted CD40 agonist, KK2269 (a bispecific antibody that binds to CD40 and EpCAM), in combination with various ...
Yuta Tezuka   +5 more
wiley   +1 more source

Growth differentiation factor 15 mitigates lipotoxic steatosis by preserving mitochondrial morphodynamics and augmenting fatty acid oxidation in hepatocytes and liver organoids

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3788-3806, May 2026.
Abstract Aims Growth differentiation factor 15 (GDF15) has emerged as a promising metabolic regulator with hepatoprotective properties in metabolic dysfunction‐associated steatotic liver disease (MASLD), yet its underlying mechanisms remain elusive.
Jia Li   +9 more
wiley   +1 more source

Mitochondrial uncoupling as a regulator of life-history trajectories in birds: an experimental study in the zebra finch. [PDF]

open access: yes, 2014
Mitochondria have a fundamental role in the transduction of energy from food into ATP. The coupling between food oxidation and ATP production is never perfect, but may nevertheless be of evolutionary significance.
Bize, P.   +5 more
core   +4 more sources

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

open access: yesDrug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Ion Transport Across a Bilayer Lipid Membrane in the Presence of Dilute Tetraphenylborate

open access: yesElectroanalysis, Volume 38, Issue 4, April 2026.
The relationship between the membrane potential and the steady‐state current was recorded by normal pulse voltammetry. It is proved that the relationship symmetrical about the origin point (0 V, 0 A) mainly results from not only the transport of TPhB− but also that of Na+ between W1 and W2 across the BLM.
Yusuke Yamada   +3 more
wiley   +1 more source

Инактивация пестицидов на основе динитрофенолов [PDF]

open access: yes, 2007
Изучена кинетика окисления 2,4- и 2,6-динитрофенолов. В качестве способа разложения выбрано окисление реактивом Фентона.
Лебедева, О. Е.   +1 more
core   +2 more sources

Molecularly Imprinted Polymer Solid-Phase Extraction (MISPE) for the Determination of Dinitro-ortho-cresol (DNOC) and Its Risk Assessment in Tomatoes [PDF]

open access: yes, 2023
In this study, the molecularly imprinted polymer solid-phase extraction (MISPE) method for the determination of dinitro-ortho-cresol (DNOC) before HPLC (High-performance liquid chromatography) analysis was conducted.
Amran, Muhammad Bachri   +4 more
core   +2 more sources

Endocrine Disruptive Effects of the Herbicides Linuron, Chloridazon and Metribuzin on Bovine Granulosa Cells

open access: yesReproduction in Domestic Animals, Volume 61, Issue 4, April 2026.
ABSTRACT Linuron, chloridazon and metribuzin are herbicides thought to have potential endocrine disruption (ED) effects. This study investigated the effects of linuron, chloridazon and metribuzin on bovine granulosa cell viability and oestrogen (E2) and progesterone (P4) secretion in vitro.
Metehan Eser Kahveci   +2 more
wiley   +1 more source

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