Results 21 to 30 of about 1,518 (175)
Would you use it with a seal of approval? Important attributes of 2,4-dinitrophenol (2,4-DNP) as a hypothetical pharmaceutical product [PDF]
Background2,4-Dinitrophenol (2,4-DNP) is an effective but highly dangerous fat burner, not licensed for human consumption. Death cases reported for 2,4-DNP overdose, particularly among young adults, have raised concerns about the ineffective regulatory ...
Ainsworth +74 more
core +3 more sources
Inhibition of adenosine triphosphatase and respiration of rat-liver mitochondria by dinitrophenols [PDF]
1. The stimulating and inhibitory effect of nitrophenols on various mitochondrial systems are compared. Both respiration and ATPase are stimulated by low dinitrophenol concentrations followed by inhibition at higher concentrations.
Hemker, H.C.
core +2 more sources
CD40 agonists have demonstrated proof‐of‐concept for converting an immunologically cold tumor into a hot tumor in preclinical studies; however, clinically, they have shown limited antitumor efficacy as monotherapy. We tested a tumor‐targeted CD40 agonist, KK2269 (a bispecific antibody that binds to CD40 and EpCAM), in combination with various ...
Yuta Tezuka +5 more
wiley +1 more source
Abstract Aims Growth differentiation factor 15 (GDF15) has emerged as a promising metabolic regulator with hepatoprotective properties in metabolic dysfunction‐associated steatotic liver disease (MASLD), yet its underlying mechanisms remain elusive.
Jia Li +9 more
wiley +1 more source
Mitochondrial uncoupling as a regulator of life-history trajectories in birds: an experimental study in the zebra finch. [PDF]
Mitochondria have a fundamental role in the transduction of energy from food into ATP. The coupling between food oxidation and ATP production is never perfect, but may nevertheless be of evolutionary significance.
Bize, P. +5 more
core +4 more sources
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley +1 more source
Ion Transport Across a Bilayer Lipid Membrane in the Presence of Dilute Tetraphenylborate
The relationship between the membrane potential and the steady‐state current was recorded by normal pulse voltammetry. It is proved that the relationship symmetrical about the origin point (0 V, 0 A) mainly results from not only the transport of TPhB− but also that of Na+ between W1 and W2 across the BLM.
Yusuke Yamada +3 more
wiley +1 more source
Инактивация пестицидов на основе динитрофенолов [PDF]
Изучена кинетика окисления 2,4- и 2,6-динитрофенолов. В качестве способа разложения выбрано окисление реактивом Фентона.
Лебедева, О. Е. +1 more
core +2 more sources
Molecularly Imprinted Polymer Solid-Phase Extraction (MISPE) for the Determination of Dinitro-ortho-cresol (DNOC) and Its Risk Assessment in Tomatoes [PDF]
In this study, the molecularly imprinted polymer solid-phase extraction (MISPE) method for the determination of dinitro-ortho-cresol (DNOC) before HPLC (High-performance liquid chromatography) analysis was conducted.
Amran, Muhammad Bachri +4 more
core +2 more sources
ABSTRACT Linuron, chloridazon and metribuzin are herbicides thought to have potential endocrine disruption (ED) effects. This study investigated the effects of linuron, chloridazon and metribuzin on bovine granulosa cell viability and oestrogen (E2) and progesterone (P4) secretion in vitro.
Metehan Eser Kahveci +2 more
wiley +1 more source

