Okadaic Acid Is at Least as Toxic as Dinophysistoxin-1 after Repeated Administration to Mice by Gavage [PDF]
Toxins, 2023 Okadaic acid (OA) and its analogues cause diarrhetic shellfish poisoning (DSP) in humans, and risk assessments of these toxins require toxicity equivalency factors (TEFs), which represent the relative toxicities of analogues.
Se Yong Park +6 more
doaj +2 more sources
Oxidative Stress Parameters and Morphological Changes in Japanese Medaka (Oryzias latipes) after Acute Exposure to OA-Group Toxins [PDF]
Life, 2022 Toxins of the OA-group (okadaic acid, OA; dinophysistoxin-1, DTX-1) are the most prevalent in the fjords of southern Chile, and are characterized by their potential harmful effects on aquatic organisms.
Diego Figueroa +5 more
doaj +2 more sources
Dissolved Algal Toxins along the Southern Coast of British Columbia Canada [PDF]
Toxins, 2023 Harmful algal blooms (HABs) in coastal British Columbia (BC), Canada, negatively impact the salmon aquaculture industry. One disease of interest to salmon aquaculture is Net Pen Liver Disease (NPLD), which induces severe liver damage and is believed to ...
Ryan B. Shartau +6 more
doaj +2 more sources
Differences in Toxic Response Induced by Three Variants of the Diarrheic Shellfish Poisoning Phycotoxins in Human Intestinal Epithelial Caco-2 Cells [PDF]
Toxins, 2020 Diarrheic shellfish poisoning (DSP) is caused by the consumption of shellfish contaminated with a group of phycotoxins that includes okadaic acid (OA), dinophysistoxin-1 (DTX-1), and dinophysistoxin-2 (DTX-2).
Antoine Huguet +4 more
doaj +2 more sources
Deciphering interactions between the marine dinoflagellate Prorocentrum lima and the fungus Aspergillus pseudoglaucus. [PDF]
Environ Microbiol, 2023 Abstract The comprehension of microbial interactions is one of the key challenges in marine microbial ecology. This study focused on exploring chemical interactions between the toxic dinoflagellate Prorocentrum lima and a filamentous fungal species, Aspergillus pseudoglaucus, which has been isolated from the microalgal culture.
Berry O +12 more
europepmc +2 more sources
Effects of Dinoflagellate Toxins Okadaic Acid and Dinophysistoxin-1 and -2 on the Microcrustacean Artemia franciscana [PDF]
ToxinsHarmful algal blooms are an expanding phenomenon negatively impacting human health, socio-economic welfare, and ecosystems. Such events increase the risk of marine organisms’ exposure to algal toxins with consequent ecological effects. In this frame, the
Federica Cavion +7 more
doaj +2 more sources
Toxins of Okadaic Acid-Group Increase Malignant Properties in Cells of Colon Cancer [PDF]
Toxins, 2020 Diarrhetic shellfish poisoning (DSP) is a syndrome caused by the intake of shellfish contaminated with a group of lipophilic and thermostable toxins, which consists of okadaic acid (OA), dinophysistoxin-1 (DTX-1) and dinophysistoxin-2 (DTX-2).
Danae Jiménez-Cárcamo +2 more
doaj +2 more sources
Dinophysis acuminata or Dinophysis acuta: What Makes the Difference in Highly Stratified Fjords? [PDF]
Marine Drugs, 2023 Dinophysis acuminata and D. acuta, which follows it seasonally, are the main producers of lipophilic toxins in temperate coastal waters, including Southern Chile.
Ángela M. Baldrich +13 more
doaj +2 more sources
Quantitation Overcoming Matrix Effects of Lipophilic Toxins in Mytilus galloprovincialis by Liquid Chromatography-Full Scan High Resolution Mass Spectrometry Analysis (LC-HR-MS) [PDF]
Marine Drugs, 2022 The analysis of marine lipophilic toxins in shellfish products still represents a challenging task due to the complexity and diversity of the sample matrix.
Camila Q. V. Costa +5 more
doaj +2 more sources
Toxins, 2015 For the first time the presence of dinophysistoxin-1 (DTX-1) in a culture of Prorocentrum foraminosum was revealed in cells and in the culture medium. The clone was isolated from coastal waters of the Sea of Japan and identified by molecular analyses of ...
Tatiana Orlova +2 more
exaly +3 more sources