Results 1 to 10 of about 2,813,688 (177)

Harnessing in Silico Design for Electrochemical Aptasensor Optimization: Detection of Okadaic Acid (OA) [PDF]

open access: yesBiosensors
The urgent need for advanced analytical tools for environmental monitoring and food safety drives the development of novel biosensing approaches and solutions.
Margherita Vit   +4 more
doaj   +4 more sources

Histone Modification Is Involved in Okadaic Acid (OA) Induced DNA Damage Response and G2-M Transition Arrest in Maize. [PDF]

open access: yesPLoS ONE, 2016
Histone modifications are involved in regulation of chromatin structure. To investigate the relationship between chromatin modification and cell cycle regulation during plant cell proliferation, Okadaic acid (OA), a specific inhibitor of serine/threonine
Hao Zhang   +8 more
doaj   +4 more sources

Isolation and Structural Identification of New Diol Esters of Okadaic Acid and Dinophysistoxin-1 from the Cultured Prorocentrum lima [PDF]

open access: yesToxins
Prorocentrum, a dinoflagellate responsible for producing diarrhetic shellfish poisoning (DSP) toxins, poses significant threats to marine ecosystems, aquaculture industries, and human health. DSP toxins, including okadaic acid (OA), dinophysis toxin (DTX)
Yeong Kwang Ji   +5 more
doaj   +2 more sources

Establishing Detection Methods for Okadaic Acid Aptamer–Target Interactions: Insights from Computational and Experimental Approaches [PDF]

open access: yesFoods
The binding interactions between okadaic acid (OA) aptamers and OA molecules are crucial for developing effective detection methods. This study aims to identify the recognition site and establish a reliable detection protocol through computational ...
Wenchong Shan   +4 more
doaj   +2 more sources

Polystyrene Microplastics Can Aggravate the Damage of the Intestinal Microenvironment Caused by Okadaic Acid: A Prevalent Algal Toxin [PDF]

open access: yesMarine Drugs
As emerging contaminants, microplastics (MPs) may pose a threat to human health. Their co-exposure with the widespread phycotoxin okadaic acid (OA), a marine toxin known to cause gastrointestinal toxicity, may exacerbate health risk and raise public ...
Hong-Jia Huang   +7 more
doaj   +2 more sources

Performance Enhancement of SPR Biosensor Using Graphene–MoS2 Hybrid Structure

open access: yesNanomaterials, 2022
We investigate a high-sensitivity surface plasmon resonance (SPR) biosensor consisting of a Au layer, four-layer MoS2, and monolayer graphene. The numerical simulations, by the transfer matrix method (TMM), demonstrate the sensor has a maximum ...
Haoyuan Cai   +4 more
doaj   +1 more source

Rapid enzyme-linked immunosorbent assay and colloidal gold immunoassay for assessing okadaic acid and its derivatives in shellfish

open access: yesFood and Agricultural Immunology, 2022
Okadaic acid (OA) and the analogs of dinophysistoxin (DTX) are important members of diarrhetic shellfish poisoning (DSP) toxins. In this study, five OA-specific mAbs (monoclonal antibodies) were developed from five stable cells of hybridoma.
Ruirui Wang   +4 more
doaj   +1 more source

Long-term exposure to low levels of okadaic acid accelerates cell cycle progression in colonic epithelial cells via p53 and Jak/Stat3 signaling pathways

open access: yesHeliyon, 2022
As a major component of diarrheic shellfish poisoning (DSP) toxins, okadaic acid (OA) is widely distributed worldwide, and causes a series of serious public health problems.
Lu Huang   +7 more
doaj   +1 more source

Okadaic acid did not change the nitrate reductase activation state in tomato seedlings

open access: yesBiologia Plantarum, 2022
In this study, the total and actual nitrate reductase (NR) activity, and NR activation state, in tomato seedlings (Solanum lycopersicum cvs. Kmicic and Faworyt) treated with okadaic acid (OA) was evaluated.
A. KOŁTON, V. VAŠTAKAITĖ-KAIRIENĖ
doaj   +1 more source

iTRAQ-Based Quantitative Proteomic Analysis Reveals Toxicity Mechanisms in Chlamys farreri Exposed to Okadaic Acid

open access: yesFrontiers in Marine Science, 2021
Okadaic acid (OA), produced by dinoflagellates during harmful algal blooms, is a principal diarrhetic shellfish poisoning toxin. This toxin poses a potential threat to bivalves with economic values.
Xin Wang   +14 more
doaj   +1 more source

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