Results 21 to 30 of about 2,813,688 (177)

Sub-Neuronal Network Profiling of Extracellular Vesicle Release Using a Compartmentalized Neurofluidic Platform. [PDF]

Adv Biol (Weinh)
This study employs a compartmentalized neurofluidic platform to map extracellular vesicle (EV) secretion dynamics with the aim of increasing the spatial resolution at sub‐neuronal locations. It examines how growth conditions, exogenous forces, and Okadaic acid treatment affect primary neurons' EV release.
Malkoc Z, Stopps E, Asamoah PMK, McCalla SE, Kunze A.   +4 more
europepmc   +2 more sources

Cross‐reactivity of highly purified okadaic acid (OA), synthetic, spiroketal east sphere of OA and ciguatoxin

Journal of Clinical Laboratory Analysis, 1992
AbstractThis study presents data from the crossreactivity analysis of purified ciguatoxin (CTX), okadaic acid (OA), and the East sphere or Fragment B‐C of OA with their homologous antibodies, monoclonal antibodies to ciguatoxin (MAb‐CTX) and okadaic acid (MAb‐OA). The test system used was the stick enzyme immunoassay. MAb‐CTX gave peak titers of 1.5ng,
Y, Hokama, T W, Hong, M, Isobe, Y, Ichikawa, T, Yasumoto   +4 more
openaire   +2 more sources

Development of a Chemiluminescent Method in a Microfluidic Device for Ultrasensitive Determination of Okadaic Acid with Highly Efficient Aptamer-Based Isolation

Separations, 2022
Rapid detection of okadaic acid (OA) in shellfish is crucial for practical application in food safety analysis. In order to establish a rapid, delicate detection scheme, an OA aptamer was utilized to quickly capture OA from the sample solution with ...
Libing Mao, Qi Zhao, Yan Yang, Sai Wang, Yiyang Dong   +4 more
doaj   +1 more source

Development of a highly sensitive and specific monoclonal antibody-based immunoassay for detection of okadaic acid in oysters and green mussels

Food and Agricultural Immunology, 2022
Okadaic acid (OA), one of marine biotoxins produced by several species of dinoflagellates, can accumulate in marine animals. The consumption of OA-contaminated seafood can cause diarrhoeic shellfish poisoning.
Cheng Liang, Yuxiang Ji, Jiyong Ma, Chundong Zhang, Hongwei Zhao   +4 more
doaj   +1 more source

Solid phase extraction for removal of matrix effects in lipophilic marine toxin analysis by liquid chromatography-tandem mass spectrometry [PDF]

, 2009
The potential of solid phase extraction (SPE) clean-up has been assessed to reduce matrix effects (signal suppression or enhancement) in the liquid chromatography-tandem mass spectrometry (LC¿MS/MS) analysis of lipophilic marine toxins.
Boer, J., de, Bire, Ronel, Bire, R., de Boer, J., de Boer, J.; id_orcid, Jacob de Boer, Boer, J. de, Mulder, Patrick P. J., McElhinney, A. M., Hess, Philipp, McElhinney, M., Philipp Hess, Gerssen, A., Mairead A. McElhinney, Gerssen, Arjen, Ronel Bire, Arjen Gerssen, Bire, L., de Boer, Jacob, Patrick P. J. Mulder, Mulder, P.P.J., Hess, P., McElhinney, Mairead A.   +22 more
core   +2 more sources

Dinophysis Toxins: Distribution, Fate in Shellfish and Impacts

Toxins, 2019
Several planktonic dinoflagellate species of the genus Dinophysis produce one or two groups of lipophilic toxins: (i) okadaic acid (OA) and its derivatives, the dinophysistoxins (DTXs), and (ii) pectenotoxins (PTXs) [...]
Beatriz Reguera, Juan Blanco
doaj   +1 more source

The insect, Galleria mellonella, is a compatible model for evaluating the toxicology of okadaic acid [PDF]

, 2019
The polyether toxin, okadaic acid, causes diarrhetic shellfish poisoning in humans. Despite extensive research into its cellular targets using rodent models, we know little about its putative effect(s) on innate immunity.
Andrew Rowley, Rowley, Andrew F, Harman, Katie, Griffiths, David J, Emery, Helena, Coates, Christopher J, Layton, Will, Christopher Coates, Lim, Jenson   +8 more
core   +1 more source

Experimental Basis for the High Oral Toxicity of Dinophysistoxin 1: A Comparative Study of DSP

Toxins, 2014
Okadaic acid (OA) and its analogues, dinophysistoxin 1 (DTX1) and dinophysistoxin 2 (DTX2), are lipophilic and heat-stable marine toxins produced by dinoflagellates, which can accumulate in filter-feeding bivalves.
Diego A. Fernández, M. Carmen Louzao, María Fraga, Natalia Vilariño, Mercedes R. Vieytes, Luis M. Botana   +5 more
doaj   +1 more source

Targets and Effects of Yessotoxin, Okadaic Acid and Palytoxin: A Differential Review

Marine Drugs, 2010
In this review, we focus on processes, organs and systems targeted by the marine toxins yessotoxin (YTX), okadaic acid (OA) and palytoxin (PTX). The effects of YTX and their basis are analyzed from data collected in the mollusc Mytilus galloprovincialis,
Enzo Ottaviani, Davide Malagoli, Antonella Franchini   +2 more
doaj   +1 more source

A rapid competitive ELISA assay of Okadaic acid level based on epoxy-functionalized magnetic beads

Food and Agricultural Immunology, 2019
Using newly designed epoxy group activated carbon shell magnetic beads as a goat against mouse antibody (G-Mab) carrier, a competitive immunoassay was conducted on the surface of G-Mab-coated magnetic beads (G-Mab-MBs).
Linjiang Pang, Haoran Quan, Ying Sun, Pingya Wang, Daifu Ma, Pengqian Mu, Tingting Chai, Yiming Zhang, Bruce D. Hammock   +8 more
doaj   +1 more source