Simple Diffusion as the Mechanism of Okadaic Acid Uptake by the Mussel Digestive Gland
Toxins, 2019 Okadaic acid (OA) and other toxins of the diarrheic shellfish poisoning (DSP) group are accumulated and transformed mainly in many bivalves, inside the digestive gland cells.
Juan Blanco +3 more
doaj +3 more sources
Proteomic analysis of hepatic effects of okadaic acid in HepaRG human liver cells
EXCLI Journal : Experimental and Clinical Sciences, 2023 The marine biotoxin okadaic acid (OA) is produced by dinoflagellates and enters the human food chain by accumulating in the fatty tissue of filter-feeding shellfish.
Leonie T. D. Wuerger +4 more
doaj +2 more sources
Okadaic acid influences xenobiotic metabolism in HepaRG cells
EXCLI Journal : Experimental and Clinical Sciences, 2022 Okadaic acid (OA) is an algae-produced lipophilic marine biotoxin that accumulates in the fatty tissue of filter-feeding shellfish. Ingestion of contaminated shellfish leads to the diarrheic shellfish poisoning syndrome.
Leonie T. D. Wuerger +5 more
doaj +2 more sources
Diverse Bacterial PKS Sequences Derived From Okadaic Acid-Producing Dinoflagellates [PDF]
Marine Drugs, 2008 Okadaic acid (OA) and the related dinophysistoxins are isolated from dinoflagellates of the genus Prorocentrum and Dinophysis. Bacteria of the Roseobacter group have been associated with okadaic acid producing dinoflagellates and have been previously ...
Kathleen S. Rein +4 more
doaj +2 more sources
Identification of 19-epi-okadaic Acid, a New Diarrhetic Shellfish Poisoning Toxin, by Liquid Chromatography with Mass Spectrometry Detection [PDF]
Marine Drugs, 2008 Okadaic acid (1) (OA) and its congeners are mainly responsible for diarrhetic shellfish poisoning (DSP) syndrome. The presence of several OA derivatives have already been confirmed in Prorocentrum and Dinophysis spp.
José J. Fernández +5 more
doaj +2 more sources
Biosensors and Bioelectronics: X, 2022 In this work, a liquid crystal (LC)-based aptasensor for okadaic acid (OA) detection was developed with a novel aptamer mechanism for enhancing the optical signals of LCs.
Zeinab Rouhbakhsh +3 more
doaj +2 more sources
In Vitro Interactions between Okadaic Acid and Rat Gut Microbiome
Marine Drugs, 2022 Okadaic acid (OA) is a marine biotoxin associated with diarrhetic shellfish poisoning (DSP), posing some threat to human beings. The oral toxicity of OA is complex, and the mechanism of toxicity is not clear. The interaction between OA and gut microbiota
Yang Liu +5 more
doaj +2 more sources
Kolaviron neuroprotective effect against okadaic acid-provoked cognitive impairment
HeliyonAlzheimer's disease (AD) is acknowledged as the main causative factor of dementia that affects millions of people around the world and is increasing at increasing pace.
Morteza Nazari-Serenjeh +9 more
doaj +2 more sources
Self-Association of Okadaic Acid: Structural and Pharmacological Significance [PDF]
Marine Drugs, 2013 Okadaic acid (OA) has been an invaluable pharmacological tool in the study of cellular signaling. The great affinity of this polyether for its targets together with its high specificity to inhibit certain protein phosphatases enables the differential ...
José J. Fernández +4 more
doaj +2 more sources
Evaluation of the study carried out by ANSES on the effectiveness of sanitary shucking of queen scallops (<i>Aequipecten opercularis</i>) contaminated by okadaic acid toxins. [PDF]
EFSA JAbstract Following a request from the European Commission, EFSA evaluated the effectiveness of sanitary shucking of queen scallops (Aequipecten opercularis) contaminated with okadaic acid (OA) group toxins. Specifically, EFSA was tasked to evaluate a study conducted by the French Agency for Food, Environmental and Occupational Health & Safety (ANSES ...
European Food Safety Authority (EFSA) +6 more
europepmc +2 more sources