Results 61 to 70 of about 9,680 (171)

The clarification of two hydroxylation steps in the conversion of cholesterol to OSW‐1 in Ornithogalum saundersiae

Plant Biotechnology Journal, Volume 23, Issue 9, Page 4030-4043, September 2025.
Summary OSW‐1 is a cholestane saponin uniquely produced in Ornithogalum saundersiae and exhibits a potential antitumor activity. The enzymes responsible for OSW‐1 biosynthesis in O. saundersiae, however, remain unclear. Herein, cholesterol was confirmed to be the precursor of OSW‐1 using stable‐isotope labeling method.
Shu‐Yue Zhang, Jian‐Qiang Kong
wiley   +1 more source

The Role of p66Shc in Cancer: Molecular Mechanisms and Therapeutic Implications

Journal of Cellular and Molecular Medicine, Volume 29, Issue 14, July 2025.
ABSTRACT p66Shc is a redox‐sensitive and pro‐apoptotic adaptor protein that regulates oxidative stress and mitochondrial apoptosis. It is the largest of three isoforms encoded by the proto‐oncogene ShcA (Src collagen homologue A). Members of the ShcA family are capable of recruiting various signalling molecules and are involved in several cellular ...
Davood Zaeifi, Khadijeh Jamialahmadi, Gholamreza Karimi   +2 more
wiley   +1 more source

Study on the extraction of dioscin by the ultrasonicassisted ethanol [PDF]

, 2014
With Dioscorea zingiberensis as row materials, and with the yield of diosgenin as assessment criteria, the effect on extraction yield of dioscin of frequency of ultrasonic, the period of ultrasonic and solidliquid ratio (D.
jing, X, Xiang, L, Jianzhong, M, yundong, S   +3 more
core   +1 more source

Effect of Increasing Yield of Dioscorea zingiberensis by Applying Potassic Fertilizer

Shuitu baochi yanjiu, 2005
The experiment indicated that potassium is one of nutrient element for the growth of Dioscorea zingiberensis,through applying potassic fertilizer can increase the yield of Dioscorea zingiberensis and economic benefit.In certain scale,applying potassic ...
DU Da-jun~1, CHEN Gang~2
doaj  

Enhancing Crop Nutrition in Arid and Semiarid Regions of Africa Through Genome Editing Using CRISPR/Cas

Food and Energy Security, Volume 14, Issue 3, May/June 2025.
ABSTRACT Food insecurity is a pressing issue in Africa, aggravated by escalating drought, jeopardizing the region's ability to meet nutritional requirements for human health. In arid and semiarid regions, crop yield is severely affected by drought and salinity.
Erick Amombo, Rita H. Mumm, Abdelaziz Nilahyane, Abdelaziz Hirich, Mohamed Hijri, Valentine Otang Ntui   +5 more
wiley   +1 more source

Enhancement of Palmarumycin C12 and C13 Production by the Endophytic Fungus Berkleasmium sp. Dzf12 in an Aqueous-Organic Solvent System

Molecules, 2015
The endophytic fungus Berkleasmium sp. Dzf12, isolated from Dioscorea zingiberensis, was found to produce palmarumycins C12 and C13 which possess a great variety of biological activities.
Yan Mou, Dan Xu, Ziling Mao, Xuejiao Dong, Fengke Lin, Ali Wang, Daowan Lai, Ligang Zhou, Bingyan Xie   +8 more
doaj   +1 more source

Phytochemical Analysis and Anti‐inflammatory Potential of Floscopa Scandens Lour. and Exploring Ecdysterone as Promising Therapeutic Agent: An HR‐LCMS Screening and Molecular Docking Analysis

ChemistrySelect, Volume 9, Issue 40, October 25, 2024.
This study analyzed the bioactive compounds of Floscopa scandens Lour. using HR‐LCMS, isolating 21 phytoconstituents, including ecdysterone as the prominent. Molecular docking and molecular dynamic simulations revealed ecdysterone's anti‐inflammatory potential, confirming its therapeutic significance.
Sailaja Nambaaru, Preeti Nanda Sahu, Sunitha Katta, Veera Raghava Sarma Ganapavarapu, Bhanukiran Kancharla, Anik Sen   +5 more
wiley   +1 more source

Diosmin: A promising phytochemical for functional foods, nutraceuticals and cancer therapy

Food Science &Nutrition, Volume 12, Issue 9, Page 6070-6092, September 2024.
The anticancer mechanisms of diosmin involve stimulating receptors, increasing ROS, and inducing cell death via the PI3K/Akt pathway. Diosmin upregulates p53 and p21, causing S‐phase cell cycle arrest, and activates caspase‐3, leading to apoptosis. Additionally, diosmin inhibits NF‐κB, reducing inflammation and angiogenesis, and promotes autophagy ...
Lubna Rahman, Ali Talha Khalil, Syed Ahsan Shahid, Zabta Khan Shinwari, Zainab M. Almarhoon, Amnah Alalmaie, Javad Sharifi‐Rad, Daniela Calina   +7 more
wiley   +1 more source

DIOSCOREA: EXPLORANDO SEU POTENCIAL NEUROPROTETOR [PDF]

Dioscorea, comumente conhecida como inhame, é um gênero de plantas tuberosas amplamente utilizado tanto na culinária quanto na medicina tradicional. Com diversas espécies distribuídas globalmente, Dioscorea é valorizada por seus compostos bioativos que ...
Miguel, Marilis Dallarmi, Pereira, Amanda de Sena Fornarolli, Miguel, Isadora Dallarmi, Ferreira, Bruna dos Santos, Santos, Brenda Winona do, Fernandes, Idonilton da Conceição   +5 more
core   +1 more source

Hepatoprotective Effect of Steroidal Glycosides From Dioscorea villosa on Hydrogen Peroxide-Induced Hepatotoxicity in HepG2 Cells

Frontiers in Pharmacology, 2018
Dioscorea villosa, commonly known as “Wild Yam” and native to North America, is well documented for its pharmacological properties due to the presence of steroidal glycosides.
Maqsood A. Siddiqui, Maqsood A. Siddiqui, Zulfiqar Ali, Amar G. Chittiboyina, Ikhlas A. Khan, Ikhlas A. Khan   +5 more
doaj   +1 more source