Results 41 to 50 of about 9,680 (171)

Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum. [PDF]

Plant Biotechnol J
ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Lim J, Kim K, Heo J, Seo SM, Choung S, Kim H, Choi Y, Park K, Yun H, Kim D, Lee ES, Lee J, Warsadiharja SM, Lee SB, Han S, Park SJ, Kim SG.   +16 more
europepmc   +2 more sources

Nephroprotective activity of natural products against chemical toxicants: The role of Nrf2/ARE signaling pathway

Food Science &Nutrition, Volume 9, Issue 6, Page 3362-3384, June 2021., 2021
The purpose of this article is to review the studies of NPs that have shown mitigating effects on renal disorder by stimulating Nrf2 and suggesting potential new therapeutic or prophylactic strategies against kidney pathogens. Abstract Nephropathy can occur following exposure of the kidneys to oxidative stress.
Emad Molaei, Ali Molaei, Farshad Abedi, A. Wallace Hayes, Gholamreza Karimi   +4 more
wiley   +1 more source

Efficient enzymatic hydrolysis of Protogracillin for clean preparation of Prosapogenin A by response surface methodology optimization

Green Chemistry Letters and Reviews, 2022
Prosapogenin A (also known as Progenin III and polyphyllin V), a secondary steroidal saponin in Dioscorea zingiberensis tubers, has more superior pharmacological activities than its primary form Protogracillin.
Haicheng Xie, Le Zhang, Shunli Jing, Jinwei Zhou, Qing Wu, Yaya Yang, Yufei Chen, Chengyu Yang, Guohua Xia, Yuping Shen, Huan Yang   +10 more
doaj   +1 more source

Ionic Liquid-Based Ultrasonic/Microwave-Assisted Extraction of Steroidal Saponins from Dioscorea zingiberensis C. H. Wright [PDF]

, 2014
Purpose: To develop a more green, efficient and low cost process for the extraction of steroidal saponins from Dioscorea Zingiberensis C. H. Wright.Methods: Six kinds of ionic liquids with different cations and anions were evaluated.
Wang, H, Ma, C, Lou, Z, Wang, P, Chen, S, Zhu, S   +5 more
core   +1 more source

Enhancement of Diosgenin Production in Plantlet and Cell Cultures of Dioscorea zingiberensis by Palmarumycin C13 from the Endophytic fungus, Berkleasmium sp. Dzf12 [PDF]

, 2015
Purpose: To study the effect of palmarumycin C13, an elicitor from the endophytic fungus Berkleasmium sp. Dzf12, on growth and diosgenin production in plantlet or cell cultures of its host plant, Dioscorea zingiberensis.Methods: Palmarumycin C13 was ...
Mou, Y, Li, J, Yin, C, Zhou, K, Xu, D, Yu, R, Zhou, L   +6 more
core   +1 more source

Ultrasound-assisted deep eutectic solvent/petroleum ether biphase system for the green and efficient production of diosgenin

Cleaner Engineering and Technology, 2022
Diosgenin, as an important precursor of steroid hormone drugs, is distributed in the root of Dioscorea Zingiberensis C. H. Wright (DZW) in the form of its sugar ligand-dioscin.
Cheng Xiang, Si Yu Zhang, Yao Che, Ge Zeng, Tao Yang   +4 more
doaj   +1 more source

Development of polymorphic microsatellite markers for Dioscorea zingiberensis and cross-amplification in other Dioscorea species

Genetics and Molecular Research, 2013
Dioscorea zingiberensis C.H. Wright (Dioscoreaceae) is an endemic species in central and southwestern China. In order to study the genetic diversity and population structure of this species, 19 novel polymorphic microsatellite loci were developed using a dual-suppression PCR technique.
Q-Q, Yan, X-Q, Sun, J-L, Guo, Y-Y, Hang, M-M, Li   +4 more
openaire   +2 more sources

Screening and Selection of a New Medium for Diosgenin Production via Microbial Biocatalysis of Fusarium sp.

Pharmaceuticals, 2021
Steroidal saponins are widely used as starting precursors and medical intermediates for the semi-/total-synthesis of hundreds of steroidal drugs. One such steroidal saponin is diosgenin, which has attracted significant attention due to the huge market ...
Wancang Liu, Haibo Xiang, Tao Zhang, Xu Pang, Jing Su, Hongyu Liu, Baiping Ma, Liyan Yu   +7 more
doaj   +1 more source

De novo transcriptome assembly and the putative biosynthetic pathway of steroidal sapogenins of Dioscorea composita. [PDF]

PLoS ONE, 2015
The plant Dioscorea composita has important applications in the medical and energy industries, and can be used for the extraction of steroidal sapogenins (important raw materials for the synthesis of steroidal drugs) and bioethanol production.
Xia Wang, Dijia Chen, Yuqi Wang, Jun Xie
doaj   +1 more source

In vitro tetraploid induction and generation of tetraploids from mixoploids in Dioscorea zingiberensis. [PDF]

Pharmacogn Mag, 2010
This article describes an efficient colchicine-mediated technique for the in vitro induction of tetraploids in Dioscorea zingiberensis and its confirmation by flow cytometry. Buds immersed in 0.2% colchicine solution for 36 hours prior to culture induced as high as 35.6% tetraploid plants. Colchicine-induced tetraploids remained stable after six months
Huang HP, Gao SL, Chen LL, Wei KH.
europepmc   +4 more sources