Potential applications of the CRISPR/Cas technology for genetic improvement of yam (Dioscorea spp.)
Yam is an economically important crop grown in the tropical and subtropical world, producing tuberous root as a staple food, and an income source for millions of farmers. Yam production is constrained by disease and pest infestations and a range of abiotic factors.
Easter D. Syombua +6 more
wiley +1 more source
Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives
Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high potential and interest in the treatment of various disorders such as cancer, diabetes, arthritis, asthma, and cardiovascular disease, in addition to being an important starting ...
Prabhakar Semwal +15 more
wiley +1 more source
Study of Saponin Components after Biotransformation of Dioscorea nipponica by Endophytic Fungi C39
This study conducted the solid fermentation process of Dioscorea nipponica using endophytic fungi C39 to determine the changes in the diosgenin concentration. The results revealed that endophytic fungi C39 could effectively biotransform the saponin components in D. nipponica.
Nannan Huang +7 more
wiley +1 more source
Different patterns of transcriptomic response to high temperature between diploid and tetraploid Dioscorea zingiberensis C. H. [PDF]
Polyploidy is an important evolutionary force in plants and may have significant impact on plant breeding. In this study, expression changes between diploid and tetraploid Dioscorea zingiberensis C. H.
Wang, X +5 more
core +1 more source
Evaluation of different pretreatments on microbial transformation of saponins in Dioscorea zingiberensis for diosgenin production. [PDF]
In order to evaluate the effects of different pretreatments on microbial transformation of saponins in Dioscorea zingiberensis (DZW), various methods have been systematically studied on a large scale. Five pretreatments, including physical separation, catalytic solvent extraction, ultrasonic fermentation, complex enzymatic hydrolyzation and enzymatic ...
Zheng T, Yu L, Zhu Y, Zhao B.
europepmc +3 more sources
Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC‐MS/MS Approach
Diosgenin, a steroidal sapogenin, has attracted attention worldwide owing to its pharmacological properties, including antitumor, cardiovascular protective, hypolipidemic, and anti‐inflammatory effects. The current diosgenin analysis methods have the disadvantages of long analysis time and low sensitivity.
Pei Liu +11 more
wiley +1 more source
Diosgenin, mainly extracted from some Dioscorea species, is the most important starting material for the production of steroidal drugs. It is believed that diosgenin in Dioscorea is synthesized from isopentenyl diphosphate (IPP) and dimethylallyl ...
Z. Cheng +4 more
doaj +1 more source
The Role of p66Shc in Diabetes: A Comprehensive Review from Bench to Bedside
It is well‐documented that diabetes is an inflammatory and oxidative disease, with an escalating global burden. Still, there is no definite treatment for diabetes or even prevention of its harmful complications. Therefore, understanding the molecular pathways associated with diabetes might help in finding a solution.
SeyedehFatemeh Mousavi +6 more
wiley +1 more source
Dioscorea sect. Stenophora (Dioscoreaceae) comprises about 30 species that are distributed in the temperate and subtropical regions of the Northern Hemisphere.
Ke Hu +11 more
doaj +1 more source
Therapeutic effects of total steroid saponin extracts from the rhizome of Dioscorea zingiberensis C.H.Wright in Freund's complete adjuvant induced arthritis in rats. [PDF]
The aim of our present study is to explore the anti-arthritic potential effect of total steroid saponins (TSSNs) extracted from the rhizome of Dioscorea zingiberensis C.H.Wright (DZW) and to investigate the underlying mechanisms.
Zhang XX +5 more
europepmc +2 more sources

