Screening and Selection of a New Medium and Culture Conditions for Diosgenin Production via Microbial Biocatalysis of SYt1 [PDF]
Diosgenin (DSG) is a phytosterol saponin mainly found in Dioscorea zingiberensis C.H. Wright. It has shown promising results in treating various diseases such as cancer, diabetes, arthritis, asthma, and cardiovascular diseases.
Shiyao Han +8 more
doaj +2 more sources
Genome-Wide Identification of CYP72A Gene Family and Expression Patterns Related to Jasmonic Acid Treatment and Steroidal Saponin Accumulation in Dioscorea zingiberensis. [PDF]
Dioscorea zingiberensis is a medicinal herb containing a large amount of steroidal saponins, which are the major bioactive compounds and the primary storage form of diosgenin.
Hou L, Yuan X, Li S, Li Y, Li Z, Li J.
europepmc +2 more sources
An HD-ZIP I Transcription Factor DZHDZ32 Upregulates Diosgenin Biosynthesis in <i>Dioscorea zingiberensis</i>. [PDF]
Diosgenin, a crucial precursor for steroidal drug production, has poorly understood regulatory pathways. Diosgenin is the primary active component of Dioscorea zingiberensis. Notably, D.
Yang H, Li Y, Hu Z, Li J.
europepmc +2 more sources
Haplotype-resolved autotetraploid genome of Dioscorea nipponica provides insights into recent polyploidization, metabolic rewiring, and environmental adaptation. [PDF]
SUMMARY Whole‐genome duplication (WGD, or polyploidization) is a major evolutionary force in plants, yet the genomic, transcriptional, and metabolic consequences of autopolyploidy remain less understood than those of allopolyploidy. Dioscorea nipponica, a medicinal species producing diosgenin‐type steroidal saponins, harbors both diploid and ...
Li SS +8 more
europepmc +2 more sources
Haplotype-resolved genome assembly of a male Dioscorea alata cultivar reveals the structure and evolution of young sex chromosomes. [PDF]
SUMMARY Dioscorea alata L., the most widely cultivated yam species, exhibits dioecy (XY system) and a strong male‐biased sex ratio. These two major constraints limit parental combinations and hinder breeding progress. To get insight into the sex chromosome structure and evolution in D.
Dossa K +20 more
europepmc +2 more sources
Direct Biotransformation of Dioscin into Diosgenin in Rhizome of Dioscorea zingiberensis by Penicillium dioscin. [PDF]
Diosgenin is an important precursor for synthesis of more than 200 steroidal hormone medicines. Rhizome of Dioscorea zingiberensis C. H. Wright (RDZ) contained the highest content of diosgenin in Dioscorea plant species. Diosgenin is traditionally extracted by acid hydrolysis from RDZ.
Dong J, Lei C, Lu D, Wang Y.
europepmc +4 more sources
The origin and evolution of the diosgenin biosynthetic pathway in yam
Diosgenin, mainly produced by Dioscorea species, is a traditional precursor of most hormonal drugs in the pharmaceutical industry. The mechanisms that underlie the origin and evolution of diosgenin biosynthesis in plants remain unclear.
Jian Cheng +11 more
doaj +1 more source
The economics and policy of genome editing in crop improvement
Abstract In this review article we analyze the economics of genome editing and its potential long‐term effect on crop improvement and agriculture. We describe the emergence of genome editing as a novel platform for crop improvement, distinct from the existing platforms of plant breeding and genetic engineering.
Nicholas Kalaitzandonakes +2 more
wiley +1 more source
Abstract Plants produce a large number of secondary metabolites, known as phytometabolites that may be employed as medicines, dyes, poisons, and insecticides in the field of medicine, agriculture, and industrial use, respectively. The rise of genome management approaches has promised a factual revolution in genetic engineering.
Sicon Mitra +10 more
wiley +1 more source
The rapid identification of sex has potential uses involving dioecious commercial plants. In this work, we first propose a rapid electrochemical analysis method for plant sex determination using the signal difference generated by the electrochemically ...
Li Fu +12 more
doaj +1 more source

