Results 41 to 50 of about 1,795 (189)

A New Class of Benzo[b]Thiophene‐1,3,4‐Oxadizole Bearing 1,2,4‐Oxadiazoles as Potent Antimicrobial Targets: Synthesis, Biological Evaluation, Docking, DFT and ADMET Studies

open access: yesChemistrySelect, Volume 11, Issue 3, 22 January 2026.
Benzo[b]thiophene‐1,3,4‐oxadizole and 1,2,4‐oxadiazole hybrids 9a–9l were tested against both antibacterial and anticancer, revealing interesting structure‐activity relationships. density functional theory calculations (DFTs) at the B3LYP/6–311++G (d,p).
Ravikumar Gupta Miriyala   +5 more
wiley   +1 more source

Cooperative Photocatalysis of 9,10‐Phenanthrenequinone and Sn(OTf)2 for Direct Mannich Reaction of Ethers via Hydrogen Atom Transfer Pathway

open access: yesAdvanced Synthesis &Catalysis, Volume 367, Issue 23, December 11, 2025.
A dual photocatalytic system of o‐PQ and Sn(OTf)2 enables visible light‐induced Mannich‐type addition of ethers to nitrones via Csp³–H activation. This oxidant‐free method offers broad scope and good yields. Mechanistic studies suggest that a photoexcited o‐PQ–Sn(II) complex mediates hydrogen atom transfer to form α‐oxy radicals for nitrone addition. A
Pradip Ramdas Thorve   +2 more
wiley   +1 more source

Nanodroplet‐Array‐Plattform zur integrierten Synthese und Screening von MEK Inhibitoren: Ein miniaturisierter Ansatz für die frühe Pharmaforschung

open access: yesAngewandte Chemie, Volume 137, Issue 48, November 24, 2025.
Wir präsentieren eine Nanodroplet‐Array‐Plattform, die die Integration von Festphasensynthese, MALDI‐MS‐Analyse und zellbasiertem Screening von 325 potenziellen MEK‐Inhibitoren (Mitogen‐aktivierte‐Proteinkinase‐Kinase) in Nanoliter‐Volumina ermöglicht.
Maximilian Seifermann   +10 more
wiley   +1 more source

Synthesis, and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents [PDF]

open access: yes
A series of twenty new chloropyrazine conjugated benzothiazepines (22-41) have been synthesized with 58%–95% yields. The compounds were characterized by using different spectroscopic techniques including FT-IR, ¹H NMR, ¹³C NMR spectroscopy and mass ...
Bhandare, R. R.   +5 more
core   +3 more sources

Enzymatic Studies of Bromocyclohexadienediols & Semi-synthesis of Narciclasine Analogues [PDF]

open access: yes, 2022
This thesis describes two projects: • cis-Diene bromo diol obtained from the microbial oxidation of bromobenzene was used as a substrate for lipase-catalyzed acylation and epoxidation reactions.
Goulart Stollmaier, Juana
core   +1 more source

Direct Carboboration of Aryl Alkenes with Stable Organoborons Through Ziegler‐Type Addition

open access: yesAdvanced Science, Volume 12, Issue 43, November 20, 2025.
The direct carboboration of vinyl arenes with benzylic boronates has been achieved using KOtBu as the catalyst. Vinylcyclopropanes and vinylcyclobutane also participate in this reaction, yielding the corresponding 1,5‐ and 1,6‐carboboration products.
Mo Yang   +5 more
wiley   +1 more source

A Meta-Analysis of 67 Studies on the Control of Grape Sour Rot Revealed Interesting Perspectives for Biocontrol [PDF]

open access: yes
Sour rot (SR) is a disease complex that affects grape berries during ripening and can cause severe yield losses and deterioration of wine quality. The etiology and epidemiology of the disease remain uncertain, which has severely limited the development ...
Brischetto C., Fedele G., Rossi V.
core   +1 more source

Boosting the Charge Output of Enclosed Liquid‐Based Nanogenerators by Electrowetting‐Assisted Charge Injection Approach

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
The study introduces an electrowetting‐assisted charge injection (EWCI) approach to significantly enhance the charge density of enclosed liquid‐based nanogenerators (EW‐NGs). By leveraging EWCI, the volumetric output charge density reaches 19.1 mC m⁻3, a ninefold improvement over the conventional methods. Successfully powering a 10‐inch LCD screen, the
Ye Zhao   +8 more
wiley   +1 more source

Radikalische C─H‐Aroylierung von Allenen mittels kooperativer Photoredox‐ und N‐heterozyklischer Carben‐Katalyse

open access: yesAngewandte Chemie, Volume 137, Issue 37, September 8, 2025.
Eine kooperative N‐heterozyklische Carben und Photoredox‐Katalyse zur C−H Benzoylierung und Veresterung von Allenen wird präsentiert. Diese Reaktion verläuft über die Kreuzkupplung von in situ generierten Ketyl‐ und Allylradikalen. Zusammenfassung Diese Studie demonstriert die Verwendung von kooperativer Photoredox‐ und N‐heterozyklischer Carben (NHC ...
Shyam Kumar Banjare   +2 more
wiley   +1 more source

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