Results 1 to 10 of about 151,994 (387)
High INDO (indoleamine 2,3-dioxygenase) mRNA level in blasts of acute myeloid leukemic patients predicts poor clinical outcome [PDF]
Haematologica, 2008 Indoleamine 2,3-dioxygenase degrades the amino acid tryptophan which is essential for T cells. Tryptophan depletion causes T-cell cycle arrest and solid tumors that express high levels of indoleamine 2,3-dioxygenase can create immune suppression ...
Martine E.D. Chamuleau +8 more
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Study on the degradation pathway of benzo[a]pyrene by Bacillus sp. strain M1 [PDF]
Frontiers in MicrobiologyBacillus sp. strain M1, originally isolated from soil contaminated with polyaromatic hydrocarbons during earlier work of our group, has a strong ability to degrade benzo[a]pyrene (BaP).
Xiaoxue Zhang +11 more
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Biodegradation of paracetamol by Amycolatopsis sp. Poz 14 [PDF]
BMC Research NotesObjective Paracetamol is widely used throughout the world and its high consumption has led to its detection in the environment as an emerging contaminant. In this work, the actinobacterium Amycolatopsis sp.
Janet Jan-Roblero +5 more
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Biomolecules, 2022 The opportunistic pathogen Pseudomonas aeruginosa uses quorum sensing to control its virulence. One of its major signal molecules, the Pseudomonas quinolone signal PQS, has high affinity to membranes and is known to be trafficked mainly via outer ...
Alba Arranz San Martín +2 more
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Frontiers in Bioengineering and Biotechnology, 2021 Molecular docking studies of quinoline and 2-chloroquinoline substrates at the active site of toluene dioxygenase (TDO), were conducted using Autodock Vina, to identify novel edge-to-face interactions and to rationalize the observed stereoselective cis ...
Derek R. Boyd +6 more
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Frontiers in Molecular Biosciences, 2022 Carotenoid metabolism is critical for diverse physiological processes. The nematode Caenorhabditis elegans has two genes that are annotated as β-carotene 15,15′-monooxygenase (BCMO) and are 17 centimorgan apart on chromosome II, but the function of BCMO ...
Weimin Pan +7 more
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Molecules, 2023 Pipecolic acid (Pip) and its derivative hydroxypipecolic acids, such as (2S,3R)-3-hydroxypipecolic acid (cis-3-L-HyPip), are components of many natural and synthetic bioactive molecules. Fe(II)/α-ketoglutaric acid (Fe(II)/2-OG)-dependent dioxygenases can
Jiaojiao Guan +5 more
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mBio, 2021 Perfluorinated carbon atoms in a diether linkage are common in commercial anesthetics, drugs, fungicides, and insecticides. An important chemical group comprising perfluorodiethers is the 2,2-fluoro-1,3-benzodioxole (DFBD) moiety.
Madison D. Bygd +3 more
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The Contribution of Plant Dioxygenases to Hypoxia Signaling
Frontiers in Plant Science, 2020 Dioxygenases catalyze the incorporation of one or two oxygen atoms into target organic substrates. Besides their metabolic role, these enzymes are involved in plant signaling pathways as this reaction is in several instances required for hormone ...
Sergio Iacopino +5 more
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Data, 2023 Fe(II)/2OG-dependent dioxygenases of the AlkB family catalyze a direct removal of alkylated damages in the course of DNA and RNA repair. A human homolog of the E. coli AlkB ALKBH3 protein is able to hydroxylate N1-methyladenine, N3-methylcytosine, and N1-
Lyubov Yu. Kanazhevskaya +3 more
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