Results 91 to 100 of about 151,994 (387)
Indonesian Journal of Biotechnology, 2010 To degrade chrysene, a polycyclic aromatic hydrocarbon (PAH), Armillaria sp. F022, a fungus collected from a soil, was used. Maximal degradation (77%) was obtained when Armillaria sp.
Tony Hadibarata, Risky Ayu Kristanti
doaj +1 more source
Enzymatic one-step ring contraction for quinolone biosynthesis. [PDF]
, 2018 The 6,6-quinolone scaffolds on which viridicatin-type fungal alkaloids are built are frequently found in metabolites that display useful biological activities.
Champagne, Pier Alexandre +7 more
core
Advanced Science, EarlyView.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Metabolic Origin, Role and Fate of the Denaturant Guanidine
Microbial BiotechnologyDespite its unusual structure and detrimental role as a chaotropic guanidinium ion, guanidine [HNC(NH2)2] exists as a genuine metabolite in many microbes, and its negative effects are mitigated by specific exporters. The metabolic origin of this molecule
Antoine Danchin +3 more
doaj +1 more source
Characterization and evaluation of catechol oxygenases by twelve bacteria, isolated from oil contaminated soils in Malaysia [PDF]
Biological Journal of Microorganism, 2017 Introduction: Catechol is a common intermediate compound in aromatic degradation process. Some microorganisms have this potentiality to degrade aromatic hydrocarbons by catechol dioxygenases to less toxic compounds with ability of entering the ...
Arezoo Tavakoli, Ainon Hamzah
doaj
Advanced Science, EarlyView.Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang +16 more
wiley +1 more source
The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.
PLoS ONE, 2012 Post-translational modification of histone proteins are known to play an important role in regulating chromatin structure. In an effort to find additional histone modifications we set out to screen enzymes of the 2-oxoglutarate and Fe(II)-dependent (2-OG-
David Lando +3 more
doaj +1 more source
Exogenous Tryptophan Promotes Cutaneous Wound Healing of Chronically Stressed Mice through Inhibition of TNF-α and IDO Activation. [PDF]
PLoS ONE, 2015 Stress prolongs the inflammatory response compromising the dermal reconstruction and wound closure. Acute stress-induced inflammation increases indoleamine 2, 3-dioxygenase-stimulated tryptophan catabolism.
Luana Graziella Bandeira +4 more
doaj +1 more source
Journal of Experimental Medicine, 2013 Indoleamine 2,3-dioxygenase suppresses infiltration and accumulation of tumor-reactive T cells in the context of anti–CTLA-4 immunotherapy and attenuates the anti-tumor efficacy.
Rikke B. Holmgaard +4 more
semanticscholar +1 more source
Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism
Advanced Science, EarlyView.Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards +8 more
wiley +1 more source