Results 11 to 20 of about 151,994 (387)
Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors in clinical trials for cancer immunotherapy
Journal of Hematology & Oncology, 2021 Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme enzyme that catalyzes the oxidation of L -tryptophan. Functionally, IDO1 has played a pivotal role in cancer immune escape via catalyzing the initial step of the kynurenine pathway, and overexpression of ...
Kai Tang, Ya-hong Wu, Yihui Song, Bin Yu
semanticscholar +1 more source
The Role of Indoleamine 2, 3-Dioxygenase 1 in Regulating Tumor Microenvironment
Cancers, 2022 Simple Summary Tumor microenvironment is a complex and dynamically changing entity, which is crucial for tumor development. Indoleamine 2, 3-dioxygenase 1 is elevated in the tumor microenvironment and is strongly associated with tumor histological ...
Xinting Huang +3 more
semanticscholar +1 more source
Indoleamine 2,3-Dioxygenase 1: A Promising Therapeutic Target in Malignant Tumor
Frontiers in Immunology, 2021 Tumorigenesis is a complex multifactorial and multistep process in which tumors can utilize a diverse repertoire of immunosuppressive mechanisms to evade host immune attacks.
Xiaotian Song +7 more
semanticscholar +1 more source
Nature Communications, 2021 Potato (Solanum tuberosum), a worldwide major food crop, produces the toxic, bitter tasting solanidane glycoalkaloids α-solanine and α-chaconine. Controlling levels of glycoalkaloids is an important focus on potato breeding. Tomato (Solanum lycopersicum)
R. Akiyama +9 more
semanticscholar +1 more source
Biomolecules, 2022 The opportunistic pathogen Pseudomonas aeruginosa employs quorum sensing to govern the production of many virulence factors. Interference with quorum sensing signaling has therefore been put forward as an attractive approach to disarm this pathogen. Here,
Alba Arranz San Martín +4 more
doaj +1 more source
Frontiers in Plant Science, 2022 To analyze the mechanisms involved in anthracene (ANT) degradation in the marine alga Ulva lactuca, total RNA was obtained from the alga cultivated without ANT and with 5 μM of ANT for 24 h, and transcriptomic analyses were performed.
Alberto González +10 more
doaj +1 more source
Application of nitroarene dioxygenases in the design of novel strains that degrade chloronitrobenzenes. [PDF]
, 2009 Widespread application of chloronitrobenzenes as feedstocks for the production of industrial chemicals and pharmaceuticals has resulted in extensive environmental contamination with these toxic compounds, where they pose significant risks to the health ...
Ju, Kou-San, Parales, Rebecca E
core +1 more source
Frontiers in Microbiology, 2019 Biotransformation of green tea catechins mediated by microbes and/or enzymes could increase their bioavailability and improve their health benefits, but the regulatory mechanism remains unclear. Here, Aspergillus niger RAF106 isolated from Pu-erh tea was
Xiang Fang +9 more
doaj +1 more source
Acta Biochimica Indonesiana, 2021 Background: Ethidium bromide is a common reagent that is used in nucleic acid staining. However, ethidium bromide has toxic and carcinogenic properties that are harmful to the environment.
Muhammad Ilham Fahri +4 more
doaj +1 more source
De novo transcriptome sequencing in Bixa orellana to identify genes involved in methylerythritol phosphate, carotenoid and bixin biosynthesis. [PDF]
, 2015 BackgroundBixin or annatto is a commercially important natural orange-red pigment derived from lycopene that is produced and stored in seeds of Bixa orellana L.
Aguilar-Espinosa, Margarita +5 more
core +3 more sources