Biosynthesis of retinal in bovine corpus luteum
Bovine corpus luteum tissue was sliced and incubated with β-[15,15′-3H]carotene. The conversion of radioactive β-carotene into radioactive retinal was substantiated utilizing column chromatography, thin-layer chromatography, high-speed liquid ...
Anthony M. Gawienowski +2 more
doaj +1 more source
Specificity of Rhodococcus opacus 1CP cells’ responses to benzoate and 3-chlorobenzoate
Background: Halogenated aromatic compounds are more resistant to microbial degradation than non-halogenated aromatic compounds. Microbial degradation of sodium benzoate in the presence of sodium 3-chlorobenzoate is of interest.
Elena V. Emelyanova, Inna P. Solyanikova
doaj +1 more source
Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer. [PDF]
Renal cell carcinoma (RCC) is increasing in incidence, and a complete cure remains elusive. While immune-checkpoint antibodies are promising, interferon-based immunotherapy has been disappointing.
Abu Aboud, Omran +13 more
core +2 more sources
The Plasma [Kynurenine]/[Tryptophan] Ratio and Indoleamine 2,3-Dioxygenase: Time for Appraisal
The plasma kynurenine to tryptophan ([Kyn]/[Trp]) ratio is frequently used to express or reflect the activity of the extrahepatic Trp-degrading enzyme indoleamine 2,3-dioxygenase (IDO).
A. Badawy, G. Guillemin
semanticscholar +1 more source
Assessment of the number of catabolic genes of oil-contaminated soils
In this work, laboratory modeling of three levels of oil contamination (60, 120 and 250 g kg–1) was carried out for three types of soil: eutric podzoluvisols, haplic greyzem, and haplic chernozems.
L.R. Biktasheva +4 more
doaj +1 more source
Diaphorobacter sp. strain JS3051 utilizes 2,3-dichloronitrobenzene (23DCNB), a toxic anthropogenic compound, as the sole carbon, nitrogen, and energy source for growth, but the metabolic pathway and its origins are unknown. Here, we establish that a gene
Tao Li +6 more
doaj +1 more source
An expanding range of targets for kynurenine metabolites of tryptophan [PDF]
The kynurenine pathway of tryptophan metabolism accounts for most of the tryptophan that is not committed to protein synthesis and includes compounds active in the nervous and immune systems.
Darlington, L. Gail +2 more
core +1 more source
The Role of Indoleamine-2,3-Dioxygenase in Cancer Development, Diagnostics, and Therapy
Tumors are composed of abnormally transformed cell types and tissues that differ from normal tissues in their genetic and epigenetic makeup, metabolism, and immunology.
Lilla Hornyák +7 more
semanticscholar +1 more source
A Sub-Type of Familial Pancreatic Cancer: Evidence and Implications of Loss-of-Function Polymorphisms in Indoleamine-2,3-Dioxygenase-2. [PDF]
BACKGROUND: Variation in an individual\u27s genetic status can impact the development of pancreatic ductal adenocarcinoma; however, the majority of familial pancreatic cancers (FPC) cannot yet be attributed to a specific inherited mutation.
Brody, Jonathan +9 more
core +2 more sources
Cloning and characterisation of a maize carotenoid cleavage dioxygenase (ZmCCD1) and its involvement in the biosynthesis of apocarotenoids with various roles in mutualistic and parasitic interactions [PDF]
Colonisation of maize roots by arbuscular mycorrhizal (AM) fungi leads to the accumulation of apocarotenoids (cyclohexenone and mycorradicin derivatives).
Beekwilder, M.J. +10 more
core +2 more sources

