Results 41 to 50 of about 125,762 (338)
Haematologica, 2010 Background The immunoregulatory enzyme indoleamine 2,3-dioxygenase, which catalyzes the conversion of tryptophan into kynurenine, is expressed in a significant subset of patients with acute myeloid leukemia, resulting in the inhibition of T-cell ...
Antonio Curti +11 more
doaj +1 more source
Enzymes Involved in Naproxen Degradation by Planococcus sp. S5 [PDF]
Polish Journal of Microbiology, 2016 Naproxen is a one of the most popular non-steroidal anti-inflammatory drugs (NSAIDs) entering the environment as a result of high consumption. For this reason, there is an emerging need to recognize mechanisms of its degradation and enzymes engaged in ...
Danuta Wojcieszyńska +3 more
doaj +1 more source
Enhanced Immunomodulation in Inflammatory Environments Favors Human Cardiac Mesenchymal Stromal-Like Cells for Allogeneic Cell Therapies [PDF]
, 2019 Rising numbers of patients with cardiovascular diseases and limited availability of donor hearts require new and improved therapy strategies. Human atrial appendage-derived cells (hAACs) are promising candidates for an allogeneic cell-based treatment. In
Diedrichs, Falk +5 more
core +1 more source
Redesign of a Dioxygenase in Morphine Biosynthesis
Chemistry & Biology, 2012 Opium poppy (Papaver somniferum) produces medicinally important benzylisoquinoline alkaloids, including the analgesics codeine and morphine, in the morphinan pathway. We aligned three dioxygenases that were recently discovered in P. somniferum and subsequently identified the nonconserved regions. Two of these enzymes, codeine O-demethylase (PsCODM) and
Weslee S. Glenn +4 more
openaire +5 more sources
Ethanol triggers grape gene expression leading to anthocyanin accumulation during berry ripening [PDF]
, 2002 Recent studies have shown that low doses of ethanol stimulate the maturation of some fruits. The present work showed that spraying Cabernet Sauvignon grapes, with 5% ethanol at veraison enhances the anthocyanin accumulation.
Chervin, Christian +9 more
core +2 more sources
Microorganisms, 2021 Microbiota from Alpine forest soils are key players in carbon cycling, which can be greatly affected by climate change. The aim of this study was to evaluate the degradation potential of culturable bacterial strains isolated from an alpine deciduous ...
Caroline Poyntner +2 more
doaj +1 more source
ChemEngineering, 2021 It is shown that bacteria Bradyrhizobium japonicum 273 were capable of degrading phenol at moderate concentrations either in a free cell culture or by immobilized cells on granulated activated carbon particles.
Evgenia Vasileva +5 more
doaj +1 more source
Translating Metabolic Reprogramming into New Targets for Kidney Cancer. [PDF]
, 2017 In the age of bioinformatics and with the advent of high-powered computation over the past decade or so the landscape of biomedical research has become radically altered.
Abu Aboud, Omran, Weiss, Robert H
core +1 more source
Hepatology, EarlyView., 2022 Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode +16 more
wiley +1 more source
Control of anthocyanin biosynthesis pathway gene expression by eutypine, a toxin from Eutypa lata, in grape cell tissue cultures [PDF]
, 2003 Eutypine, 4-hydroxy-3-(3-methyl-3-butene-1-ynyl) benzaldehyde, is a toxin produced by Eutypa lata, the causal agent of Eutypa dieback in grapevine. The effect of the toxin on anthocyanin synthesis has been investigated in Vitis vinifera cv.
Afifi, Maha +6 more
core +2 more sources