Synthesis, X-ray Structures, Electronic Properties, and O\u3csub\u3e2\u3c/sub\u3e/NO Reactivities of Thiol Dioxygenase Active-Site Models [PDF]
, 2016 Mononuclear non-heme iron complexes that serve as structural and functional mimics of the thiol dioxygenases (TDOs), cysteine dioxygenase (CDO) and cysteamine dioxygenase (ADO), have been prepared and characterized with crystallographic, spectroscopic ...
Brunold, Thomas C. +4 more
core +1 more source
Advanced Science, EarlyView.A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding +5 more
wiley +1 more source
Divergent Pseudomonas aeruginosa LpxO enzymes perform site-specific lipid A 2-hydroxylation
mBioPseudomonas aeruginosa can survive in a myriad of environments, partially due to modifications of its lipid A, the membrane anchor of lipopolysaccharide.
Casey E. Hofstaedter +7 more
doaj +1 more source
Biomedicines, 2018 Hypoxia-inducible transcription factors (HIFs) facilitate cellular adaptations to low-oxygen environments. However, it is increasingly recognised that HIFs may be activated in response to metabolic stimuli, even when oxygen is present.
Peter S. J. Bailey, James A. Nathan
doaj +1 more source
Four Bacillus sp. soil isolates capable of degrading phenol, toluene, biphenyl, naphthalene and other aromatic compounds exhibit different aromatic catabolic potentials [PDF]
Archives of Biological Sciences, 2011 Two novel Bacillus sp. were isolated from a soil sample from a bank of the Tamiš river in close proximity to a petrochemical facility. They were capable of utilizing a broad range of aromatic compounds as a sole source of carbon and energy (including ...
Đokić Lidija +4 more
doaj +1 more source
5-hydroxymethylcytosine is a key epigenetic regulator of keratinocyte stem cells during psoriasis pathogenesis [PDF]
, 2019 Epigenetic regulation is now known to play an important role in determining stem cell fate during normal tissue development and disease pathogenesis. In this study, we report loss of 5-hydroxymethylcytosine (5-hmC) mediated by ten-eleven translocation ...
Yuan, Christine Wan-Yin
core
Interplay between carotenoids, abscisic acid and jasmonate guides the compatible rice-Meloidogyne graminicola interaction [PDF]
, 2017 In this study, we have characterized the role of carotenoids and chlorophyll in the compatible interaction between the sedentary root knot nematode (RKN) Meloidogyne graminicola and the monocot model plant rice (Oryza sativa). Previous transcriptome data
Demeestere, Kristof +5 more
core +2 more sources
Advanced Science, EarlyView.Domestication of Tartary buckwheat is selected for a salt tolerance mechanism involving the magnesium transporter FtMGT2. Its expression is controlled by the FtAGL16‐FtMYB15L module, which is stabilized under salt stress through a competitive interaction that blocks its degradation by the E3 ligase FtBRG1, ultimately boosting Na⁺ efflux and plant ...
Xiang Lu +23 more
wiley +1 more source
TET1 displays catalytic and non-catalytic functions in the adult mouse cortex
EpigeneticsTET1/2/3 dioxygenases iteratively demethylate 5-methylcytosine, beginning with the formation of 5-hydroxymethylcytosine (5hmC). The post-mitotic brain maintains higher levels of 5hmC than most peripheral tissues, and TET1 ablation studies have ...
Yee Hoon Foong +7 more
doaj +1 more source
Purification and kinetic studies of recombinant gibberellin dioxygenases
BMC Plant Biology, 2005 Background The 2-oxoglutarate-dependent dioxygenases (2ODDs) of gibberellin (GA) biosynthesis have a key role in the metabolism of a major plant hormone.
Hedden Peter +3 more
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