Results 141 to 150 of about 59,947 (268)

Probiotics as a Strategy for Mitigating Viral Infections in Poultry: Immunomodulatory Mechanisms and Therapeutic Potential

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Probiotics—particularly Lactobacillus acidophilus, L. casei and L. plantarum—may mitigate NDV, AIV and IBV infections by modulating immunity, supporting gut microbiome and barrier function, and enhancing vaccine responses, although stronger strain‐specific, safety, mechanistic and field‐based evidence is needed. ABSTRACT Poultry viral infections remain
Elmer Nayra Ametefe, Daniel Saka, Juliet Nuerkie Anang, Lourraine Sena Doh, Leonard Kofi Adjorlolo   +4 more
wiley   +1 more source

Recombinant versus native botulinum neurotoxin type A: structural and pharmacodynamic comparison

Acta Crystallographica Section F, Volume 82, Issue 11, Page 391-401, November 2026.
For the first time, the recombinant core botulinum neurotoxin type A (BoNT/A) expressed in Escherichia coli and nicked in vitro is shown to be structurally identical to native BoNT/A from Clostridium botulinum, enabling direct activity comparison between the recombinant product and the native toxin.Botulinum neurotoxins (BoNTs) are highly potent ...
Zongren Yao, Lingyi Xu, Yu Lu, Hui Gong, Xiaoyun Sun, Yaokun Zhao, Jinhuan Chen, Liming Yang, Qingqing Chen, Wu Yang   +9 more
wiley   +1 more source

A Dipeptide Module Substitution-Based Strategy for the Modification and Evaluation of ACE Inhibitory Peptides. [PDF]

Foods
Liang Q, Wang S, Sun N, Zhu C, Liu Z, Mou H.   +5 more
europepmc   +1 more source

Tree species identity is associated with rhizosphere microbiome assembly via root metabolite‐mediated feedbacks in subtropical forests

Functional Ecology, Volume 40, Issue 11, Page 3542-3558, November 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The rhizosphere microbiome is critical for forest ecological functions, yet the mechanisms through which tree species identity and neighbour tree interactions are associated with its assembly remain poorly understood.
Yuemei Zhang, Junchen Ye, Yao Kang, Yangchunzi Liao, Ziwen Jiao, Wenjing Meng, Lin Chang, Bing Liu, Yilin Li, Ziwen Gao, Ning Li, Hui Sun, Lin Huang   +12 more
wiley   +1 more source

A nanobiotechnological approach to control non‐persistent aphid‐transmitted plant viruses, based on functionalized virus‐like particles

Annals of Applied Biology, Volume 189, Issue 3, November 2026.
A potyvirus‐derived virus‐like nanoparticle (VLP) interferes in the transmission by aphids of the non‐circulative plant viruses turnip mosaic virus (TuMV, Potyvirus), zucchini yellow mosaic virus (ZYMV, Potyvirus), and cucumber mosaic virus (CMV, Cucumovirus) is also observed. The construct, that consisted of a fusion between a modified TuMV HC‐Pro and
Aranzazu Moreno, Inmaculada Ferriol, Lucia Zurita, Maria Plaza, Rocio Galán‐Cubero, Adriana Urbano‐Bernabé, Alberto Fereres, Fernando Ponz   +7 more
wiley   +1 more source

Substrate‐Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis

Angewandte Chemie, Volume 138, Issue 44, 26 October 2026.
Substitutions in the aminopyruvatide precursor peptide altered the C─C linkage formed from a YLY motif by the P450 ApyO to a N─C linkage in a WLY motif. Moreover, constitutional isomers crosslinked by C─C and C─O linkages were formed from YYY or YWY motifs. ABSTRACT Cytochrome P450s catalyze an array of reactions including crosslinking of aromatic side
Chandrashekhar Padhi, Dinh T. Nguyen, Lingyang Zhu, Lide Cha, Jesse W. Wald, Douglas A. Mitchell, Wilfred A. van der Donk   +6 more
wiley   +2 more sources

Dipeptide Synthesis - Alanine and Valine

We plan to use alanine and valine to synthesize a dipeptide using the carbodiimide compound EDC. We will use Boc- protection to protect the N-terminus of alanine and esterification to protect the C-terminus of valine.
Nguyen, Nick, Monroe, Abby
core   +1 more source

Antioxidant and free radical scavenging potential of feruloyl amino acids and dipeptide derivatives: an experimental and theoretical investigation. [PDF]

RSC Adv
Amine Khodja I, Spiegel M, Hamed A, Abid S, Abid M, Alsalamah SA, Kato MJ, Boulebd H.   +7 more
europepmc   +1 more source

A Cilia–Centered Nicotinamide Adenine Dinucleotide (NAD+) Signaling Network Regulates Hypothalamic Lysosomal Homeostasis and Metabolic Aging

Aging Cell, Volume 25, Issue 11, November 2026.
Aging‐associated NAD+ depletion in hypothalamic neurons shortens primary cilia and disrupts CHMP4B trafficking to lysosomes during lysosomal stress, leading to impaired TRPML1–mediated Ca2+ signaling and lysosomal stress responses. Calorie restriction restores hypothalamic NAD+ levels, ciliary structure, and lysosomal homeostasis, thereby improving ...
Se Eun Park, Eun Roh, Jae Woo Park, Seong Jun Kim, So Yeon Jeong, Chae Beom Park, Hyo Sun Lim, Ji Soo Kim, Mun Gyeom Kim, Myeong Ju Kim, Young In Cho, Wontae Jeong, Gil Myoung Kang, Sang‐Yeob Kim, Se Hee Min, Min‐Seon Kim   +15 more
wiley   +1 more source

Using structure to evaluate the accuracy and transferability of machine learning potentials of biomolecules. [PDF]

RSC Adv
Biberić LŠ, Joshi N, Pfaendtner J.
europepmc   +1 more source