Results 11 to 20 of about 12,907 (206)

Angioedema associated with dipeptidyl peptidase-IV inhibitors. [PDF]

Clin Mol Allergy, 2021
Abstract Background Dipeptidyl peptidase-IV (DPP-IV) inhibitors, also known as gliptins, are a class of oral antidiabetic agents. Postmarketing reports have documented the occurrence of angioedema in patients treated with gliptins and it was found that these drugs increased the risk of angioedema in patients concurrently
Cassano N, Nettis E, Di Leo E, Ambrogio F, Vena GA, Foti C.   +5 more
europepmc   +5 more sources

Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia [PDF]

Journal of Neuroinflammation, 2012
Background Cerebral inflammation is a hallmark of neuronal degeneration. Dipeptidyl peptidase IV, aminopeptidase N as well as the dipeptidyl peptidases II, 8 and 9 and cytosolic alanyl-aminopeptidase are involved in the regulation of autoimmunity and ...
Röhnert Peter, Schmidt Werner, Emmerlich Patrick, Goihl Alexander, Wrenger Sabine, Bank Ute, Nordhoff Karsten, Täger Michael, Ansorge Siegfried, Reinhold Dirk, Striggow Frank   +10 more
doaj   +2 more sources

Identification of potential dipeptidyl peptidase IV inhibitors from the ConMedNP library by virtual screening, and molecular dynamics methods [PDF]

Heliyon
In this study, we screened novel dipeptidyl peptidase IV (DPP4) inhibitors from the ConMedNP library consisting of 3507 molecules. Interestingly, molecular docking, ADMET, and the anti-diabetic activity predictions suggest that three molecules, namely ...
Hans Merlin Tsahnang Fofack, Maraf Mbah Bake, Simon Petry, Baruch A. Ateba, Pascal Amoa Onguéné, Haydar Mohammad-Salim, Fidele Ntie-Kang, Luc Meva'a Mbaze, Serhii Vakal, Cyril A Kenfack   +9 more
doaj   +2 more sources

Dipeptidyl peptidase IV inhibitors as novel regulators of vascular disease [PDF]

Vascular Pharmacology, 2017
Dipeptidyl peptidase IV (DPP-IV) has been revealed as an adipokine with potential relevance in cardiovascular disease (CVD), while clinically used DPP-IV inhibitors have demonstrated beneficial cardiovascular effects in several experimental studies. Perivascular adipose tissue (PVAT) is a unique adipose tissue depot in close anatomical proximity and ...
Akoumianakis, I, Antoniades, C
openaire   +6 more sources

Tackling dipeptidyl peptidase IV in neurological disorders [PDF]

Neural Regeneration Research, 2018
Dipeptidyl peptidase IV (DPP-IV) is a serine protease best known for its role in inactivating glucagon-like peptide-1 (GLP-1), pituitary adenylate cyclase-activating polypeptide (PACAP) and glucose-dependent insulinotropic peptide (GIP), three ...
Ghaith Al-Badri, Gian Marco Leggio, Giuseppe Musumeci, Rubina Marzagalli, Filippo Drago, Alessandro Castorina   +5 more
doaj   +3 more sources

Dipeptidyl peptidase IV inhibitors derived from a mangrove flora Rhizophora mucronata: An in silico approach [PDF]

Bangladesh Journal of Pharmacology, 2012
Dipeptidyl peptidase IV (DPP IV) is responsible for conversion of glucose tolerance (GLP-1), into inactive form. The inhibition of DPP IV would be beneficial in the treatment of diabetes mellitus.
Selvaraj Gurudeeban, Kaliyamurthi Satyavani, Thirugnanasambandam Ramanathan, Palanisamy Ravikumar   +3 more
doaj   +2 more sources

The roles of dipeptidyl peptidase-4 inhibitors in prognosis of COVID-19 infection in patients with type 2 diabetes mellitus

Journal of Research in Medical Sciences, 2022
Background: COVID-19 is responsible for the latest pandemic. Dipeptidyl peptidase-4 (DPP-4) is one of the cellular receptors of interest for coronavirus. The aim of this study was to assess the roles of DPP-4 inhibitors in prognosis of COVID-19 infection
Mohammad Sadidi, Ahad Zare, Mehrdad Nasrollahzadehsabet, Farzaneh Dastan, Ali Mosadegh Khah, Milad Jafari Asheyani   +5 more
doaj   +1 more source

Increased Risk of Hospitalization for Heart Failure with Newly Prescribed Dipeptidyl Peptidase-4 Inhibitors and Pioglitazone Using the Korean Health Insurance Claims Database [PDF]

Diabetes & Metabolism Journal, 2015
BackgroundWe assessed the association of dipeptidyl peptidase 4 inhibitors (DPP4i) with hospitalization for heart failure (HF) using the Korean Health Insurance claims database.MethodsWe collected data on newly prescribed sitagliptin, vildagliptin, and ...
Sunghwan Suh, Gi Hyeon Seo, Chang Hee Jung, Mee-Kyoung Kim, Sang-Man Jin, You-Cheol Hwang, Byung-Wan Lee, Jae Hyeon Kim   +7 more
doaj   +1 more source

Dipeptidyl Peptidase (DPP)-IV Inhibitors with Antioxidant Potential Isolated from Natural Sources: A Novel Approach for the Management of Diabetes

Pharmaceuticals, 2021
Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia that is predominantly caused by insulin resistance or impaired insulin secretion, along with disturbances in carbohydrate, fat and protein metabolism.
Anand-Krishna Singh, Dhananjay Yadav, Neha Sharma, Jun-O Jin   +3 more
doaj   +1 more source

Brown goat yogurt: Metabolomics, peptidomics, and sensory changes during production

Journal of Dairy Science, 2023
: Brown goat milk products have gained popularity for their unique taste and flavor. The emergence of chain-reversal phenomenon makes the design and development of goat milk products gradually tend to a consumer-oriented model.
R. Zhang, W. Jia
doaj   +1 more source