Results 91 to 100 of about 66,268 (303)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Hyperglycemia, glucose fluctuations, and thyroid dysfunction contribute to the progression of diabetic nephropathy. This study aimed to investigate the associations of glycemia, glucose variability, and thyroid hormones with albuminuria in patients with type 2 diabetes mellitus (T2DM). In total, 451 T2DM patients were included.
Na Luo +12 more
wiley +1 more source
Novel Dipeptidyl Peptidase-4–Inhibiting Peptide Derived From β-Lactoglobulin
Journal of Pharmacological Sciences, 2011 .: Trypsin-treated β-lactoglobulin significantly decreased the glucose level after an oral glucose tolerance test using mice. We performed the present study to identify the active peptide inhibiting dipeptidyl peptidase-4 from trypsin-treated β ...
Masayuki Uchida +2 more
doaj +1 more source
Detection of peptidases in Trypanosoma cruzi epimastigotes using chromogenic and fluorogenic substrates [PDF]
, 2017 Detergent extracts of Trypanosoma cruzi epimastigotes catalysed the hydrolysis of a range of amino-acyl and peptidyl p-nitro-anilides and aminomethylcoumarins. At least three enzymes were detected that cleave Z-Phe-Arg-MCA.
Ashall, F. +6 more
core
2. tüüpi diabeedi ravimid IV: DPP-4 inhibiitorid [PDF]
, 2009 DPP-4 inhibiitorid ehk gliptiinid on kõige uuem ravimrühm 2. tüüpi diabeedi ravis.
Volke, Vallo
core +2 more sources
Dipeptidyl peptidase-4 (DPP-4; CD26) [PDF]
Science-Business eXchange, 2013 Cell culture studies identified DDP-4 as the receptor of human coronavirus–Erasmus Medical Center (hCoV-EMC) and suggest that blocking the protein could help treat infection.
openaire +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
Med Research, EarlyView.The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Clinical Case Reports, 2020 We experienced two cases of dipeptidyl peptidase‐4 (DPP‐4) inhibitor‐associated bullous pemphigoid (BP) showing an unfavorable course despite its discontinuation.
Yasutake Shinohara +8 more
doaj +1 more source
Microbiota Medicine Research, EarlyView.ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai +6 more
wiley +1 more source
An open-label pilot study on preventing glucocorticoid-induced diabetes mellitus with linagliptin
Journal of Medical Case Reports, 2018 Background Numerous patients develop diabetes in response to glucocorticoid therapy. This study explored the efficacy, safety, and preventive potential of the dipeptidyl peptidase-4 inhibitor, linagliptin (TRADJENTA®), in the development of ...
Yoshia Miyawaki +12 more
doaj +1 more source
Obesity, EarlyView.ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu +13 more
wiley +1 more source