Results 141 to 150 of about 41,710 (302)

Dipeptidyl Peptidase 4 Inhibitor, an Update [PDF]

open access: yesThe Journal of Korean Diabetes, 2021
openaire   +1 more source

Diabetic foot ulcer‐related amputation is associated with twofold increased risk of cardiovascular disease: A Korean National Health Information Database Study

open access: yesJournal of Diabetes Investigation, EarlyView.
Data/Design: Nationwide, population‐based longitudinal cohort using the Korean National Health Insurance Service health checkup database (index 2009–2012) with follow‐up through December 31, 2018. Population/Exposure: Adults with diabetes (N = 1,229,689); DFU‐related amputation at baseline (n = 1,486) vs no DFU‐related amputation.
Jinsun Jang   +11 more
wiley   +1 more source

Dipeptidyl peptidase-4 inhibitors and osteoporosis

open access: yesJournal of the Chinese Medical Association, 2022
Wen-Ling Lee, Fa-Kung Lee, Peng-Hui Wang
openaire   +1 more source

Recent advances in incretin biology and therapeutics: From glucose‐dependent insulinotropic polypeptide reappraisal to next‐generation agonists

open access: yesJournal of Diabetes Investigation, EarlyView.
Future directions in incretin research: Three major directions currently shape therapeutic innovation in incretin research: multi‐receptor agonism, oral drug development, and mechanistic reappraisal of glucose‐dependent insulinotropic polypeptide (GIP) physiology.
Sodai Kubota, Yutaka Seino, Daisuke Yabe
wiley   +1 more source

Five‐year follow‐up of incretin‐based therapy in a patient with KCNJ11‐related permanent neonatal diabetes: Achieving insulin discontinuation and sulfonylurea reduction

open access: yesJournal of Diabetes Investigation, EarlyView.
In a woman with KCNJ11‐related permanent neonatal diabetes mellitus, incretin‐based therapy enabled insulin discontinuation and maintained glycemic control for more than 5 years, with HbA1c between 6.1% and 6.5% on the lowest semaglutide dose, dose‐dependent improvement in insulin secretion, and an approximately 60% reduction in glibenclamide dose ...
Toshiaki Ohkuma   +4 more
wiley   +1 more source

Life‐threatening acute complications persist among individuals with type 1 diabetes in Japan: A nationwide registry‐based cross‐sectional study

open access: yesJournal of Diabetes Investigation, EarlyView.
Despite insulin therapy, 18.8 and 7.8% of the patients experienced diabetic ketosis and diabetic ketoacidosis, respectively. Furthermore, 12.7 and 28.9% of the participants experienced severe hypoglycemia and hypoglycemic unawareness, respectively. Lower C‐peptide levels were associated with the incidence of these complications.
Daisuke Chujo   +7 more
wiley   +1 more source

Impact of COVID‐19 restrictions and their relaxation on body composition and glycemic control in individuals with glucose intolerance in Japan: A single‐center observational study

open access: yesJournal of Diabetes Investigation, EarlyView.
This study examined glycemic control, body composition, and lifestyle changes in 221 outpatients with glucose intolerance (GI) in Japan across the pre‐state of emergency (SOE), SOE, and post‐SOE periods. HbA1c increased despite body weight reduction, with progressive muscle loss.
Ami Kobayashi   +6 more
wiley   +1 more source

Sodium–glucose cotransporter 2 inhibition and injection burden in mild diabetic macular edema: An exploratory post hoc analysis of the COMET trial

open access: yesJournal of Diabetes Investigation, EarlyView.
Combining oral sodium‐glucose cotransporter 2 inhibitors with reduced intravitreal injections of anti‐vascular endothelial growth factor showed potential efficacy for mild diabetic macular edema. ABSTRACT Aims To investigate the potential of sodium–glucose cotransporter 2 inhibitors (SGLT2i) as a less invasive treatment option for mild diabetic macular
Yoko Takatsuna   +6 more
wiley   +1 more source

Linagliptin: from bench to bedside

open access: yesDrug Design, Development and Therapy, 2014
John DoupisIatriko Palaiou Falirou Medical Center, Division of Diabetes, Athens, GreecePurpose: The nature of biomedical research affords a broad range of investigational topics at the preclinical stage, not all of which may be explored in subsequent ...
Doupis J
doaj  

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