Results 161 to 170 of about 21,027 (334)

Nano‐plastics disrupt systemic metabolism by remodeling the bile acid–microbiota axis and driving hepatic–intestinal dysfunction

iMeta, EarlyView.
The pervasiveness of microplastic pollution poses a growing health risk, yet its long‐term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanoparticle (NP) and combined histopathology, biochemistry, metabolomics, and metagenomics to resolve their interactions.
Yi Zhang, Zheng Lin, Runtong Huang, Yang Zhang, Lei Wang, Zan Fu, Chao Wang, Shuai Xiao, Heru Pramono, Kui Xu, Zhimin Xu, Yulong Yin   +11 more
wiley   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Wild‐Derived House Mice (Mus musculus) Are Able to Cope With a Constant Light Environment

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Exposure to altered nighttime lighting conditions has become common in today's modern world. Light at night disrupts circadian processes that govern feeding patterns, sleep/wake cycles, and metabolic homoeostasis, increasing the risk of developing pathologies associated with cardiometabolic disease. Yet, the underlying mechanism(s) responsible
Kevin Pham, KayLene Y. H. Yamada, Emma M. Rhodes, Agata. M. Rudolf, Wendy R. Hood   +4 more
wiley   +1 more source

Flagellar Radial Spokes Contain a Ca ²⁺ -stimulated Nucleoside Diphosphate Kinase

, 2004
Ramila S. Patel‐King, Oksana Gorbatyuk, Sachiko Takebe, Stephen M. King   +3 more
openalex   +1 more source

The Effect of Tetra-sodium 2-Methyl-1: 4-Naphthohydroquinone Diphosphate (Synkayvite) on a Variety of Malignant Tumours in Experimental Animals [PDF]

, 1950
Alfred Gellhorn, Tersa Gagliano
openalex   +1 more source

Functional Characterization of ent-Copalyl Diphosphate Synthase and Kaurene Synthase Genes from Coffea arabica L

, 2023
Suzana Tiemi Ivamoto, José M. Celedón, Macaire M. S. Yuen, Cíntia Sorane Good Kitzberger, Douglas Silva Domingues, Jörg Bohlmann, Luiz Filipe Protásio Pereira   +6 more
openalex   +1 more source

From mechanism to phenotype: What fits in a basket trial

Epilepsia, EarlyView.
Kette D. Valente
wiley   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

Journal of Intelligent Medicine, EarlyView.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran, Tarique Mahmood, Farogh Ahsan, Shahzadi Bano, Vaseem Ahamad Ansari, Mohd Adnan   +5 more
wiley   +1 more source

Phenotypes of Fission Yeast Defective in Ubiquinone Production Due to Disruption of the Gene for p -Hydroxybenzoate Polyprenyl Diphosphate Transferase

, 2000
Naonori Uchida, Kengo Suzuki, Ryoichi Saiki, Tomohiro Kainou, Katsunori Tanaka, Hideyuki Matsuda, Makoto Kawamukai   +6 more
openalex   +2 more sources

Differential Uridyl-diphosphate-Glucuronosyl Transferase 1A enzymatic arsenal explains the specific cytotoxicity of resveratrol towards tumor colorectal cells [PDF]

, 2022
Samuel Amintas, Pauline Beaumont, Charles Dupin, Isabelle Moranvillier, Isabelle Lamrissi, Elie Patel, Benjamı́n Fernández, alice Bibeyran, Julian Boutin, Tristan Richard, Stéphanie Krisa, François Moreau‐Gaudry, Aurélie Bedel, David Cappellen, Benoı̂t Pinson, V. Vendrely, Sandrine Dabernat   +16 more
openalex   +1 more source