Results 81 to 90 of about 13,112 (302)

Prediction of Cardiac ATTR Depletion by NI006 (ALXN2220) Using Mechanistic PK/PD Modeling

Clinical Pharmacology &Therapeutics, Volume 117, Issue 1, Page 261-269, January 2025.
NI006 (aka ALXN2220) is a therapeutic antibody candidate in phase III clinical development for the depletion of amyloid transthyretin (ATTR) in patients with ATTR cardiomyopathy, an infiltrative cardiomyopathy leading to increased left ventricular wall thickness (LVWT).
Aubin Michalon, Lionel Renaud, Matthias Machacek, Cédric Cortijo, Chandrasekhar Udata, Michele F. Mercuri, Fabian Buller, Christoph Hock, Roger M. Nitsch, Peter C. Kahr, Jan Grimm   +10 more
wiley   +1 more source

Analysis of the Degree of Information of Dental Surgeons about Antiresorptive Drugs According to the Time Since Graduation in Dentistry

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2023
Objective: To determine the level of scientific information of dental surgeons who carry out their professional activities in Brazil about antiresorptive drugs and indicated pharmacological procedures aiming at the prevention of osteonecrosis of the jaws
Flávia Godinho Costa Wanderley Rocha, Roberto Paulo Correia de Araújo   +1 more
doaj  

Single Dose Therapy of Zoledronic Acid for the Treatment of Transient Osteoporosis of Hip [PDF]

Annals of Rehabilitation Medicine, 2019
Objective To shorten the natural course of transient osteoporosis of hip (TOH), which is a self-limiting idiopathic condition and requires 6–12 months for the resolution of symptoms, various therapies including treatment with bisphosphonates have been ...
Sanjay Agarwala, Mayank Vijayvargiya
doaj   +1 more source

A Two‐Stage CNN‐Based Method for Enhanced Metastasis Segmentation in SPECT Bone Scans

International Journal of Intelligent Systems, Volume 2025, Issue 1, 2025.
Accurate segmentation of metastatic lesions is crucial for improving the quality of patient care, particularly in the context of bone scans. However, existing automated methods, which are predominantly data‐driven, exhibit limited performance and lack interpretability.
Yang He, Qiang Lin, Zhengxing Man, Yongchun Cao, Xianwu Zeng, Xiaodi Huang, Vittorio Memmolo   +6 more
wiley   +1 more source

Bone Grafts in Jaw Cysts- Hydroxyapatite & Allogenic Bone A Comparative Study [PDF]

, 2009
Background: Auto bone is the gold standard in bone grafting. However, the morbidity and additional surgical time associated with its collection, as well as the limited supply, have stimulated the search for substitutes.
Akhter, Mahmuda, Mamun, Showkat, Molla, Motiur Rahman   +2 more
core   +3 more sources

Prevalence and characteristics of transthyretin amyloid cardiomyopathy in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 11, Issue 6, Page 4314-4324, December 2024.
Abstract Aims Recognition of transthyretin amyloid cardiomyopathy is increasing due to advances in cardiac imaging and diagnostic strategies, but questions remain regarding disease frequency and characteristics. We examined the prevalence and characteristics of transthyretin amyloid cardiomyopathy in older patients with hypertrophic cardiomyopathy of ...
Pablo Garcia‐Pavia, Thibaud Damy, Nicolas Piriou, Roberto Barriales‐Villa, Francesco Cappelli, Catherine Bahus, Carmen Munteanu, Denis Keohane, Pablo Mallaina, Perry Elliott, on behalf of the TTRACK investigators   +10 more
wiley   +1 more source

Treatment of hypercalcaemia in thyrotoxicosis with aminohydroxypropylidene diphosphonate [PDF]

Postgraduate Medical Journal, 1988
Summary Two patients had symptomatic hypercalcaemia accompanying thyrotoxicosis, despite initial treatment with volume repletion, beta blockade and antithyroid drugs. They were further managed with intravenous infusions of aminohydroxypropylidene diphosphonate resulting in rapid normalization of the serum calcium, with relief of symptoms.
A. A. Alzaid, I.T. Boyle, J. A. Thomson, T. T. Tan, N. Sutcliffe, M. D. Gardner   +5 more
openaire   +3 more sources

Surface chemistry of heterobimetallic Ge-M (M = Mo, W) complexes in zeolite Y. [PDF]

, 1991
The intrazeolite chemistry of the two germylene complexes Cl2CTHF)GeM(CO)5 (M = Mo, W) was studied with x-ray absorption spectroscopy (Ge, Mo, W edge EXAFS) and in-situ FTIR/TPD-MS techniques.
Bein, Thomas, Borvornwattananont, Aticha, Möller, Karin   +2 more
core   +1 more source

Artificial intelligence and radiomics applied to prostate cancer bone metastasis imaging: A review

iRADIOLOGY, Volume 2, Issue 6, Page 527-538, December 2024.
Overview of inclusion criteria for this review. The medical domain is metastatic prostate cancer to the bone. The imaging modalities are radiologic and nuclear imaging (X‐ray, CT, MRI, positron emission tomography, positron emission tomography‐computer tomography, scintigraphy).
S. J. Pawan, Joseph Rich, Jonathan Le, Ethan Yi, Timothy Triche, Amir Goldkorn, Vinay Duddalwar   +6 more
wiley   +1 more source

miR827 orchestrates the regulation of SPX‐MFS1 and SPX‐MFS5 with the assistance of lncRNA767 to enhance phosphate starvation tolerance and maize development

Plant Biotechnology Journal, Volume 22, Issue 12, Page 3489-3504, December 2024.
Summary MicroRNA827 (miR827) is functionally conserved among different plant species and displays species‐specific characteristics, but the mechanisms by which miR827 regulates phosphate (Pi) starvation tolerance and maize development remain elusive. We found that miR827 selectively targets the Pi transporter genes SPX‐MFS1 and SPX‐MFS5.
Lei Chen, Juan He, Xufeng Wang, Shiru Zhang, Jinkang Pan, Jianxiang Peng, Beixin Mo, Lin Liu   +7 more
wiley   +1 more source