Results 111 to 120 of about 16,833 (195)
Intranasal vaccination induces pulmonary neutrophil accumulation and SLPI release, accompanied by changes in soluble mediators associated with tissue remodelling, coagulation, and total IgA. ABSTRACT Vaccines delivered via the nasal route have attracted increasing attention for their capacity to engage the mucosal immune system at the primary site of ...
Oktawia Osiecka +7 more
wiley +1 more source
On day 0 adult male and female rats were injected with Stable Substance P‐Saporin (SSP‐SAP) at 4 unilateral sites along the longitudinal axis of the dentate gyrus. Rats exhibited spontaneous electrographic and behavioral reactive seizures between days 4‐6. There was a progressive loss of CA1 and CA3 neurons and a progressive increase in astrocytes over
Srijal Gupta +4 more
wiley +1 more source
Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang +14 more
wiley +1 more source
This study, ‘The Diphtheria Disease’ explored the historical significance, etiology, symptoms, transmission, and preventive measures related to diphtheria. The study adopted a qualitative meta-analysis approach.
Muekara Friday Dugbor
core +1 more source
ABSTRACT Background Primary care is an important setting for prevention, but implementation gaps may arise before clinicians can identify patients eligible for preventive services. We described self‐reported preventive care implementation among Japanese primary care physicians and examined whether lower implementation co‐occurred with eligibility ...
Hironori Yamada +7 more
wiley +1 more source
Cancer Neuroscience: From Local Neuro–Immune Microenvironments to Systemic Brain–Body Circuitry
This review outlines the cancer neuroscience paradigm, spanning systemic brain–body circuitry and local neuro–immune–tumor microenvironments. We discuss how tumors promote axonogenesis and pseudo‐synapse formation, and how sensory neuropeptides, such as CGRP, contribute to CD8+ T‐cell exhaustion.
Mingxuan Xie +7 more
wiley +1 more source
ABSTRACT Under‐5 child mortality due to vaccine preventable diseases (VPDs) contributes to an estimated burden of ∼5.2 million deaths globally, mostly within low‐ and middle‐income countries (LMICs). Despite ongoing efforts to expand immunisation coverage, gaps in immunisation remain a persistent public health concern, underscoring the need to examine ...
Mansi Malik +3 more
wiley +1 more source
Background Diphtheria is a re-emerging infectious disease and public health concern worldwide and in Vietnam with increasing cases in recent years. This study aimed to assess the anti-diphtheria toxoid antibodies status in Khanh Hoa Province and identify
Hoang Thieu Le +11 more
doaj +1 more source
ABSTRACT Objective The Tetanus, Diphtheria, Pertussis (Tdap, “tetanus”) vaccine is recommended for adults every 10 years. In a national sample of adult emergency department (ED) patients, we sought to determine (1) knowledge and up‐to‐date status of the tetanus vaccine; (2) reasons for nonreceipt of the vaccine; (3) vaccine acceptability if offered in ...
Francesco Sergi +11 more
wiley +1 more source

