Results 111 to 120 of about 120,287 (198)
BMC Infectious DiseasesBackground Diphtheria is a re-emerging infectious disease and public health concern worldwide and in Vietnam with increasing cases in recent years. This study aimed to assess the anti-diphtheria toxoid antibodies status in Khanh Hoa Province and identify
Hoang Thieu Le +11 more
doaj +1 more source
Pharmacy‐Based Immunization Delivery: A Comprehensive History and Current Challenges
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 6, June 2026.ABSTRACT Pharmacists and their teams have a long history of involvement with vaccines. This paper describes the contributions of pharmacy‐based immunization delivery in the United States from the 1800's to date. Early activities centered around storage and distribution of antitoxins and vaccines. From the 1950s through the early 1990s, pharmacists were
Jean‐Venable R. Goode +4 more
wiley +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.This study explores the interaction between Diphtheria Toxin (DT) and Bcl‐2 in HT‐29 cells. Integrating molecular docking with gene expression analysis, we demonstrate DT's high‐affinity binding to Bcl‐2 and a significant downregulation of BCL2 mRNA. These findings suggest that DT modulates anti‐apoptotic pathways, influencing colorectal cancer cell ...
Elif Ercan +3 more
wiley +1 more source
Diphtheria's disturbing comeback: an alarming resurgence in Pakistan
Journal of the Pakistan Medical AssociationDear Respected Editor, Diphtheria, caused by Corynebacterium diphtheria, affects the throat and nasopharynx. Transmission occurs through airborne respiratory droplets, secretions, or direct contact. Toxigenic strains produce diphtheria toxin (DT) that
Wajiha Fatima Khan +4 more
doaj +1 more source
Acromegaly Presenting With Cricoarytenoid Joint Arthropathy
The Laryngoscope, Volume 136, Issue 6, Page 2678-2680, June 2026.Excess growth hormone in acromegaly induces characteristic acral and soft tissue overgrowth (particularly in the face and hands), arthropathies, as well as cardiovascular and metabolic complications. Similar proliferative changes can occur in the larynx, where hypertrophy of the arytenoid and cricoid cartilages may impair vocal fold mobility.
Samantha Salvi Cruz +3 more
wiley +1 more source
Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.We generated Thy1‐Cre–driven GCaMP8 transgenic rats by mating Thy1‐Cre rats with knock‐in rats carrying a floxed GCaMP8‐STOP cassette in the β‐actin locus. Robust neuronal GCaMP8 expression enabled transcranial calcium imaging of the auditory cortex, establishing this model as a powerful tool for minimally invasive cortical macro‐imaging and functional
Manavu Tohmi +10 more
wiley +1 more source
Organ Medicine, Volume 3, Issue 2, Page 76-86, June 2026.Cancer‐associated fibroblasts (CAFs) are key regulators of the pancreatic tumor microenvironment. Through metabolic reprogramming, CAFs support tumor growth by providing nutrients and remodeling extracellular matrix. CAF heterogeneity, including myCAF, iCAF, and apCAF subsets, contributes to immune modulation and therapeutic resistance.
Ziyi Qin, Jinyang Ma, Rui Ju, Lei Guo
wiley +1 more source
A Case for Anti‐IgE Vaccination
Allergy, Volume 81, Issue 6, Page 2001-2013, June 2026.ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff +3 more
wiley +1 more source