Results 91 to 100 of about 120,814 (189)

EVALUATION OF DIPHTHERIA SURVEILLANCE SYSTEM IN PROBOLINGGO DISTRICT: STUDY OF SYSTEM APPROACH AND ATTRIBUTES

open access: yesJurnal Berkala Epidemiologi
Background: There is still an outbreak of diphtheria in the Probolinggo district in 2023. Diphtheria mainly affects children who are not immunized. Support through a surveillance system is needed to overcome the diphtheria problem.
Lidya Nur Maulina   +4 more
doaj   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer   +5 more
wiley   +1 more source

A population-level analysis of armed conflict and diphtheria at the subnational level in the WHO African Region 2017–2024

open access: yesBMC Global and Public Health
Background Diphtheria has been re-emerging around the world at alarming rates, raising concerns about emergency preparedness, especially when global supplies of life-saving diphtheria antitoxin are insufficient.
Tierney O’Sullivan, Lindsay T. Keegan
doaj   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, Volume 26, Issue 8, Page 9-28, August 2026.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

Replacement soaking for human tankyrase 2 enables studies on substrate analogues and inhibitors

open access: yesActa Crystallographica Section D, Volume 82, Issue 8, Page 998-1008, August 2026.
Replacement soaking, also known as cross‐soaking, is a compelling method for solving complex structures in cases where traditional soaking and co‐crystallization approaches fail. This method is demonstrated with human tankyrase 2, and new crystal structures of complexes with nanomolar inhibitors and an analogue of the substrate NAD+ are reported ...
Johan Pääkkönen   +3 more
wiley   +1 more source

CLINICO–Demographic Profile and Outcomes of Hospitalised Children With Diphtheria in A Tertiary Care Hospital of Peshawar

open access: yesActa Paediatrica, Volume 115, Issue 8, Page 1646-1653, August 2026.
ABSTRACT Aim To determine the clinico‐demographic profile and predictors of mortality in hospitalised children with diphtheria. Methods This retrospective cohort study included 202 children aged 5–16 years diagnosed with diphtheria per WHO criteria at Lady Reading Hospital, Peshawar, from January 2023 to December 2024. Data on demographics, vaccination
Amir Muhammad   +6 more
wiley   +1 more source

Prevention of microglial activation and postoperative cognitive deficits by positive allosteric modulation of α5‐GABAA receptors

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 16, Page 4836-4854, August 2026.
Background and Purpose Long‐lasting cognitive deficits after surgery in aged individuals, referred to as perioperative neurocognitive disorder (NCD), are a significant public health concern. Such postoperative cognitive deficits are dependent on the presence of microglia in the brain, which, when activated, trigger neuroinflammation.
Jinrui Lyu   +9 more
wiley   +1 more source

Italian Delphi Consensus on Maternity Care in Multiple Sclerosis: Toward an Interdisciplinary Model of Care

open access: yesEuropean Journal of Neurology, Volume 33, Issue 8, August 2026.
ABSTRACT Background Reproductive health is a critical component of care for women with multiple sclerosis (MS), yet standardized interdisciplinary approaches remain limited. Objectives This Delphi consensus aimed to develop an interdisciplinary, evidence‐informed care model tailored to the Italian healthcare system.
Emilio Portaccio   +13 more
wiley   +1 more source

Life Course Malaria Exposure and SARS‐CoV‐2 Seroepidemiology in Ugandan Adolescents: A Longitudinal Study Nested in a Birth Cohort

open access: yesTropical Medicine &International Health, Volume 31, Issue 8, Page 1012-1027, August 2026.
ABSTRACT Background COVID‐19 has had major global health impacts, yet reported morbidity and mortality have been lower in Africa despite serological evidence of widespread infection. Malaria has been proposed as a potential modifier of susceptibility to and outcomes of SARS‐CoV‐2 infection.
Ludoviko Zirimenya   +22 more
wiley   +1 more source

Home - About - Disclaimer - Privacy