Results 81 to 90 of about 16,833 (195)
Perspectives on Pertussis Prevention
Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley +1 more source
British Journal of Haematology, EarlyView.Summary Over the past decade, there has been a substantial increase in the diversity and number of therapeutic options for myeloproliferative neoplasms (MPNs). While many remain within the clinical trial arena, the clinician and patient community have seen more approvals reaching the clinic and a rethink on how best we should be approaching these ...
Trung Q. Ngo +3 more
wiley +1 more source
New biosensors and transgenic mice for multiplex cGMP imaging
British Journal of Pharmacology, EarlyView.Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters +6 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley +1 more source
Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides
Angewandte Chemie, Volume 138, Issue 36, 1 September 2026.Well‐defined α(2,8)‐ and α(2,9)‐linked oligosialic acids of different lengths can be prepared by employing recombinant bacterial polysialyltransferases in combination with chemically modified CMP‐Neu5Ac derivatives. After transfer, a sialoside is formed bearing an artificial entity, which blocks further glycosylation.
Jelle A. Fok +4 more
wiley +2 more sources
Клінічна та профілактична медицина, 2019 The goal of the work – to present the analysis of epidemiological monitoring of anti-diphtheria protection of the population of Dnepropetrovsk region, to show the generalizing epidemiological situation of diphtheria, to substantiate the need for the ...
G. O. Revenko +2 more
doaj +1 more source
Prevention of Pertussis, Tetanus, and Diphtheria with Vaccines in the United States : Recommendations of the Advisory Committee on Immunization Practices (ACIP) [PDF]
This report compiles and summarizes all recommendations from CDC\u2019s Advisory Committee on Immunization Practices (ACIP) regarding prevention and control of tetanus, diphtheria, and pertussis in the United States.
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Daraxonrasib and Beyond: Pan‐RAS Inhibition, Resistance, and Next‐Generation Strategies
Cancer Science, EarlyView.ABSTRACT RAS proteins have long been considered difficult therapeutic targets, but allele‐selective inhibitors established the clinical tractability of mutant RAS. Daraxonrasib (RMC‐6236), an oral pan‐RAS inhibitor, has now extended this concept by targeting multiple mutant and wild‐type RAS proteins.
Ryo Honda
wiley +1 more source
On the Relationship of the Pseudo-Diphtheria to the Diphtheria Bacillus [PDF]
Journal of Hygiene, 1905 The extreme diversity of opinion as to the identity of the Klebs-Loeffler bacillus and the bacillus of Hofmann, and the importance of the subject from the public health standpoint, make it desirable to bring forward any facts which may assist in arriving at a solution of the problem.
openaire +2 more sources
, 1895 Contains "report of the first series of 25 cases of diphtheria treated with antitoxine--New Orleans."Contains appendices A-D: p. 53-54 ; and A-D: p.
Diphtheria Antitoxine Commission of New Orleans.
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