Results 31 to 40 of about 120,814 (189)

Autochthonous outbreak of respiratory diphtheria caused by Corynebacterium diphtheriae, Germany, September 2024

open access: yesEurosurveillance
In September 2024, a school-aged child (P1), unvaccinated against diphtheria, was hospitalised with severe respiratory diphtheria caused by toxigenic Corynebacterium diphtheriae. P1 subsequently died from the disease.
Andreas Sing
doaj   +1 more source

Differential diagnosis diphtheria adults

open access: yesЖурнал инфектологии, 2014
A total of 1,824 human cases of diphtheria, treated at the Clinical Infectious Diseases Hospital SP Botkin (St. Petersburg) during 1993, as well as 19 deaths in 1994.
Yu. I. Liashenko   +4 more
doaj   +1 more source

A deterministic mathematical model for optimal control of diphtheria disease with booster vaccination

open access: yesHealthcare Analytics, 2023
Diphtheria is an infectious disease caused by a strain of Corynebacterium diphtheria and forms part of the childhood vaccine-preventable diseases. The Diphtheria vaccine is a component of one of the routine vaccines given to children thrice before their ...
Chinwendu E. Madubueze   +2 more
doaj   +1 more source

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu   +20 more
wiley   +1 more source

Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans

open access: yesEmerging Infectious Diseases, 2019
Corynebacterium ulcerans infection is emerging in humans. We conducted phylogenetic analyses of C. ulcerans and C. diptheriae, which revealed diverse diphtheria toxin in C. ulcerans.
Ken Otsuji   +3 more
doaj   +1 more source

Targeting DNGR‐1 with Fangchinoline Elevates Dendritic Cell Antigen Cross‐Presentation‐Mediated Antitumor Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao   +19 more
wiley   +1 more source

RISK FACTORS ASSOCIATED TO DIPHTHERIA OUTBREAK IN DEVELOPING COUNTRIES [PDF]

open access: yesJurnal Ilmu Kesehatan Masyarakat, 2018
Background: Diphtheria is a vaccine preventable disease. In the last 10 years a significant fluctuation of diphtheria incidence led to an outbreak reported in some developing countries. The aim of this study was to review about risk factors in developing
Aderia Rintani   +4 more
doaj   +1 more source

GAMBARAN KARAKTERISTIK DAN STATUS IMUNISASI PENDERITA DIFTERI DI PROVINSI JAWA TIMUR TAHUN 2018

open access: yesJurnal Ilmu Kesehatan Masyarakat, 2019
In 2016 East Java was the region with the highest cases of diphtheria, namely 209 cases with 6 deaths. In 2017 diphtheria cases in East Java increased to 460 cases with 16 deaths, and continued to increase in 2018, namely 758 cases with a death rate of 3
Dwi Rismayanti Wigrhadita
doaj   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

open access: yesAngewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber   +4 more
wiley   +1 more source

The evolution of pertactin expression in Belgian circulating B. pertussis strains, pre- and post-COVID-19

open access: yesMicrobiology Spectrum
Prior to the COVID-19 pandemic, Bordetella pertussis strains not producing pertactin were globally increasing, especially in countries using the acellular pertussis vaccine. Subsequently, during the pandemic, global pertussis incidence dropped to extreme
Helena Martini   +6 more
doaj   +1 more source

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