Results 31 to 40 of about 142,634 (201)

Rare manifestations of cutaneous diphtheria: a case report

Journal of Medical Case Reports
Background This case report presents an exceptionally rare and atypical presentation of diphtheria in a 17-year-old female of Hausa ethnicity residing in an area with an elevated incidence within Kano State, Nigeria.
Salma Ali Suwaid, Aliyu Mustapha, Monika Ried, Ruqayyah Ali Muhammad, Aminu Shehu Liman, Salma Yusuf   +5 more
doaj   +1 more source

Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans

Emerging Infectious Diseases, 2019
Corynebacterium ulcerans infection is emerging in humans. We conducted phylogenetic analyses of C. ulcerans and C. diptheriae, which revealed diverse diphtheria toxin in C. ulcerans.
Ken Otsuji, Kazumasa Fukuda, Midori Ogawa, Mitsumasa Saito   +3 more
doaj   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Diphtheria.

, 2020
Diphtheria is a potentially fatal infection mostly caused by toxigenic Corynebacterium diphtheriae strains and occasionally by toxigenic C. ulcerans and C. pseudotuberculosis strains.

core   +2 more sources

A deterministic mathematical model for optimal control of diphtheria disease with booster vaccination

Healthcare Analytics, 2023
Diphtheria is an infectious disease caused by a strain of Corynebacterium diphtheria and forms part of the childhood vaccine-preventable diseases. The Diphtheria vaccine is a component of one of the routine vaccines given to children thrice before their ...
Chinwendu E. Madubueze, Kazeem A. Tijani, Fatmawati   +2 more
doaj   +1 more source

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

Advanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami, Sanad M. El‐Khatib, Suhas Sureshchandra, Elise Nguyen, Janaki Manoja Vinnakota, Robert Zeiser, Shivashankar Othy, Munjal M. Acharya   +7 more
wiley   +1 more source

GAMBARAN KARAKTERISTIK DAN STATUS IMUNISASI PENDERITA DIFTERI DI PROVINSI JAWA TIMUR TAHUN 2018

Jurnal Ilmu Kesehatan Masyarakat, 2019
In 2016 East Java was the region with the highest cases of diphtheria, namely 209 cases with 6 deaths. In 2017 diphtheria cases in East Java increased to 460 cases with 16 deaths, and continued to increase in 2018, namely 758 cases with a death rate of 3
Dwi Rismayanti Wigrhadita
doaj   +1 more source

RISK FACTORS ASSOCIATED TO DIPHTHERIA OUTBREAK IN DEVELOPING COUNTRIES [PDF]

Jurnal Ilmu Kesehatan Masyarakat, 2018
Background: Diphtheria is a vaccine preventable disease. In the last 10 years a significant fluctuation of diphtheria incidence led to an outbreak reported in some developing countries. The aim of this study was to review about risk factors in developing
Aderia Rintani, Tita Mintarsih, Yosef Muhammad Rachman Baniaz Muliawan, Juli Sapitri Siregar, Adhy Prasetyo Widodo   +4 more
doaj   +1 more source

Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition

Advanced Science, EarlyView.
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu, Luyao Ji, Haoyi Yang, Xiying Chen, Qiaodan Hu, Haimei He, Jiawei Wu, Leyan Shan, Shihui Feng, Yingzhi Li, Xiongchang Tan, Hao Wang, Zilong Wang, Chaoran Wu   +13 more
wiley   +1 more source

The evolution of pertactin expression in Belgian circulating B. pertussis strains, pre- and post-COVID-19

Microbiology Spectrum
Prior to the COVID-19 pandemic, Bordetella pertussis strains not producing pertactin were globally increasing, especially in countries using the acellular pertussis vaccine. Subsequently, during the pandemic, global pertussis incidence dropped to extreme
Helena Martini, Oriane Soetens, Vili Niinikoski, Alex-Mikael Barkoff, Qiushui He, Denis Piérard, Eveline Van Honacker   +6 more
doaj   +1 more source