Results 41 to 50 of about 120,287 (198)

Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans

Emerging Infectious Diseases, 2019
Corynebacterium ulcerans infection is emerging in humans. We conducted phylogenetic analyses of C. ulcerans and C. diptheriae, which revealed diverse diphtheria toxin in C. ulcerans.
Ken Otsuji, Kazumasa Fukuda, Midori Ogawa, Mitsumasa Saito   +3 more
doaj   +1 more source

Autochthonous outbreak of respiratory diphtheria caused by Corynebacterium diphtheriae, Germany, September 2024

Eurosurveillance
In September 2024, a school-aged child (P1), unvaccinated against diphtheria, was hospitalised with severe respiratory diphtheria caused by toxigenic Corynebacterium diphtheriae. P1 subsequently died from the disease.
Andreas Sing
doaj   +1 more source

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

Advanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu, Edgar E. Perez Carbajal, Yih‐Chii Hwang, Sahil A. Mapkar, Benjamin W. Gilman, Sarah A. Bliss, Lam B. Tran, Kalgi T. Mehta, Jacob O. Banyasz, Ming Yu, Reynold R. Liu, Matthew N. Ly, Christapher S. Morrissey, Michael N. Wosczyna   +13 more
wiley   +1 more source

Rare manifestations of cutaneous diphtheria: a case report

Journal of Medical Case Reports
Background This case report presents an exceptionally rare and atypical presentation of diphtheria in a 17-year-old female of Hausa ethnicity residing in an area with an elevated incidence within Kano State, Nigeria.
Salma Ali Suwaid, Aliyu Mustapha, Monika Ried, Ruqayyah Ali Muhammad, Aminu Shehu Liman, Salma Yusuf   +5 more
doaj   +1 more source

RISK FACTORS ASSOCIATED TO DIPHTHERIA OUTBREAK IN DEVELOPING COUNTRIES [PDF]

Jurnal Ilmu Kesehatan Masyarakat, 2018
Background: Diphtheria is a vaccine preventable disease. In the last 10 years a significant fluctuation of diphtheria incidence led to an outbreak reported in some developing countries. The aim of this study was to review about risk factors in developing
Aderia Rintani, Tita Mintarsih, Yosef Muhammad Rachman Baniaz Muliawan, Juli Sapitri Siregar, Adhy Prasetyo Widodo   +4 more
doaj   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source

GAMBARAN KARAKTERISTIK DAN STATUS IMUNISASI PENDERITA DIFTERI DI PROVINSI JAWA TIMUR TAHUN 2018

Jurnal Ilmu Kesehatan Masyarakat, 2019
In 2016 East Java was the region with the highest cases of diphtheria, namely 209 cases with 6 deaths. In 2017 diphtheria cases in East Java increased to 460 cases with 16 deaths, and continued to increase in 2018, namely 758 cases with a death rate of 3
Dwi Rismayanti Wigrhadita
doaj   +1 more source

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

Advanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu, Weimin Feng, Zitian He, Jiayi Zeng, Jingyi Tang, Shulin Li, Tongbo Yu, Sulei Fu, Hui Ma, Binbin Lu, Yanmei Liu, Ji‐Feng Fei   +11 more
wiley   +1 more source

The Relationship Between Knowledge of Mother and Family Support with Immunization Status Td in Sub PIN Difteri

Jurnal Berkala Epidemiologi, 2014
The number cases of diphtheria in East Java have increased more years. Surabaya is one of cities that implemented the Sub Pekan Imunisasi Nasional (PIN) Diphtheria.
Ishmatul Fajriyah
doaj   +1 more source