Results 41 to 50 of about 93,758 (212)
Advanced Science, EarlyView.Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie +9 more
wiley +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease classification is based on histopathologic review and immunohistochemical staining of an appropriate skin ...
Alexandra C. Hristov +2 more
wiley +1 more source
Populations Addressed in Vaccines Approved via the European Medicines Agency
Clinical Pharmacology &Therapeutics, EarlyView.Therapeutic and prophylactic agents require robust evidence before patient use. Randomized controlled trials are essential for evaluating safety and efficacy but often exclude specific populations that are also targets for the intervention. This study assessed which populations are included in vaccine registration studies and/or addressed in label ...
Débora D. Gräf +3 more
wiley +1 more source
Is Diphtheria Booster Vaccination Still Necessary in Turkey?
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2018 Introduction: Diphtheria is a serious disease that can be prevented by vaccination. The aim of the study was to determine immunity against diphtheria and the necessity of booster doses in the adult population.Materials and Methods: Serum antibody levels ...
Sule Eren CAKAR +5 more
doaj +1 more source
Oligodendrogenesis in Evolution, Development and Adulthood
Glia, EarlyView.Oligodendrocytes and myelin took shape in jawed vertebrates. During development, OPCs are originated from NSCs and then undergo differentiation into mature oligodendrocytes that supply myelin. OPCs persist in the adult CNS and continue to produce oligodendrocytes and myelin. Adaptive myelination, which fine‐tunes neural circuits in response to neuronal
Hao Hu +3 more
wiley +1 more source
International Journal of Infectious Diseases, 2020 Objective: To determine the seroprevalence of antibodies against of diphtheria, tetanus, and pertussis among Thai adolescents. Methods: A cross-sectional study was conducted among Thai adolescents aged 11–20 years who had completed five doses of ...
Pimpika Hanvatananukul +7 more
doaj
Pediatric Rheumatology Online Journal, 2021 Background Immunosuppressive drugs, incomplete vaccine coverage, immune system dysregulation might be factors of a low level of anti-vaccine antibodies in JIA patients. The study aimed to evaluate vaccine coverage, post-vaccine immunity, and risk factors
Mikhail M. Kostik +4 more
doaj +1 more source
Clinical progress note: Pertussis
Journal of Hospital Medicine, EarlyView.Abstract Pertussis, commonly known as whooping cough, is a vaccine‐preventable respiratory disease with rising incidence due to declining vaccination rates and waning immunity. The most severe disease course is seen in unvaccinated or incompletely vaccinated infants less than 2 months of age, accounting for the largest burden of hospitalization and ...
Samantha Hanna, Nicole Samies
wiley +1 more source
Pediatric Discovery, EarlyView.The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao +6 more
wiley +1 more source