Results 131 to 140 of about 542,716 (249)

Ion channel and membrane translocation of diphtheria toxin

, 1992
Diphtheria toxin is the best studied member of a family of bacterial protein toxins which act inside cells. To reach their cytoplasmic targets, these toxins, which include tetanus and botulinum neurotoxins and anthrax toxin, have to cross the hydrophobic
MONTECUCCO, CESARE, ROSSETTO, ORNELLA, PADOVAN E, PAPINI, EMANUELE, SCHIAVO G   +4 more
core   +1 more source

Potency of a human monoclonal antibody to diphtheria toxin relative to equine diphtheria anti-toxin in a guinea pig intoxication model

, 2017
Prompt administration of anti-toxin reduces mortality following Corynebacterium diphtheriae infection. Current treatment relies upon equine diphtheria anti-toxin (DAT), with a 10% risk of serum sickness and rarely anaphylaxis.
Leney, Mark, Barton, Bruce A, Smith, Heidi L., Molrine, Deborah C., Cheslock, Peter S.   +4 more
core   +1 more source

Evaluation of antidiphtheria toxin nanobodies

Nanotechnology, Science and Applications, 2010
Ghada H ShakerDepartment of Microbiology and Immunology, Faculty of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi ArabiaAbstract: Nanobodies are the smallest fragments of naturally occurring single-domain antibodies that have evolved to be ...
Ghada H Shaker
doaj  

Determination of Diphtheria Toxin in Bacterial Cultures by Enzyme Immunoassay. [PDF]

Diagnostics (Basel), 2022
Simonova MA, Melnikov VG, Lakhtina OE, Komaleva RL, Berger A, Sing A, Zavriev SK.   +6 more
europepmc   +1 more source

Diphtheria toxin-derived, anti-PD-1 immunotoxin, a potent and practical tool to selectively deplete PD-1⁺ cells. [PDF]

Protein Sci, 2023
Zhang T, Dong S, Zhai Y, Naatz L, Zhou Z, Chen M.   +5 more
europepmc   +1 more source

A novel murine model of atrial fibrillation by diphtheria toxin-induced injury. [PDF]

Front Physiol, 2022
Trieu T, Mach P, Bunn K, Huang V, Huang J, Chow C, Nakano H, Fajardo VM, Touma M, Ren S, Wang Y, Nakano A.   +11 more
europepmc   +1 more source

Comparative whole-genome analysis of diphtheria toxin-producing Corynebacterium ulcerans isolates from sheltered cats in Osaka, Japan. [PDF]

J Vet Med Sci, 2023
Umeda K, Hirai Y.
europepmc   +1 more source

Effect of electroporation-mediated diphtheria toxin A expression on PSA positive human prostate xenograft tumors in SCID mice

, 2010
Current therapies to treat prostate cancer are often limited. Since it has been shown that very low concentrations of diphtheria toxin A (DT-A) result in abrogation of protein synthesis and apoptosis of cells, DT-A might serve as an efficient killer in ...
Goepfert, Christine, Amiq Gazdhar, Brigitte M. Frey, Felix J. Frey, Frey, Felix J, Christine Goepfert, Frey, Brigitte M, Gazdhar, Amiq   +7 more
core   +1 more source

Detection of diphtheria toxin production by toxigenic corynebacteria using an optimized Elek test. [PDF]

Infection, 2022
Melnikov VG, Berger A, Sing A.
europepmc   +1 more source

Dual recombinase-mediated endothelial cell-specific lineage tracing and ablation

Cell Regeneration
The precise ablation of specific cell lineages is crucial for functional studies in vivo. Conventional methods, like the Cre-dependent iDTR system, are constrained by the off-target effects and variable efficiency of single-recombinase approaches.
Jie Li, Mingjun Zhang, Xiuxiu Liu, Zhenqian Zhang, Mengyang Shi, Wenjuan Pu, Bin Zhou   +6 more
doaj   +1 more source