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Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197
E. Malito +13 more
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Tat-dependent conditionally replicating adenoviruses expressing diphtheria toxin A for specifically killing HIV-1-infected cells. [PDF]
Ni F +8 more
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Diphtheria Toxin Receptor Complex.
MEKADA, Eisuke +2 more
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Effect of Diphtheria Toxin-Based Gene Therapy for Hepatocellular Carcinoma. [PDF]
Kamimura K +12 more
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Protective monoclonal antibodies to diphtheria toxin
Maria das Graças M. Danelli +3 more
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The crystal structure of diphtheria toxin
Nature, 1992The crystal structure of the diphtheria toxin dimer at 2.5 A resolution reveals a Y-shaped molecule of three domains. The catalytic domain, called fragment A, is of the alpha + beta type. Fragment B actually consists of two domains. The transmembrane domain consists of nine alpha-helices, two pairs of which are unusually apolar and may participate in ...
S, Choe +6 more
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Crystallization of diphtheria toxin
Journal of Molecular Biology, 1991Two new crystal forms (forms III and IV) have been grown of diphtheria toxin (DT), which kills susceptible cells by catalyzing the ADP-ribosylation of elongation factor 2, thereby stopping protein synthesis. Forms III and IV diffract to 2.3 A and 2.7 A resolution, respectively.
G, Fujii +3 more
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