Results 191 to 200 of about 542,716 (249)

A transgenic mouse model of inducible macrophage depletion: effects of diphtheria toxin-driven lysozyme M-specific cell lineage ablation on wound inflammatory, angiogenic, and contractive processes.

American Journal of Pathology, 2009
Itamar Goren, Nadine Allmann, N. Yogev, C. Schürmann, A. Linke, M. Holdener, A. Waisman, J. Pfeilschifter, S. Frank   +8 more
semanticscholar   +1 more source

Protective monoclonal antibodies to diphtheria toxin

Memorias do Instituto Oswaldo Cruz, 1991
Maria das Graças M. Danelli, Lúcia M. Teixeira, Luiz Carlos D. Formiga, J. Mauro Peralta   +3 more
doaj   +1 more source

Diphtheria toxin; the iron enzymes of Corynebacterium diphtheriae and their possible relation to diphtheria toxin.

The Journal of biological chemistry, 2010
A M, PAPPENHEIMER, E D, HENDEE
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The crystal structure of diphtheria toxin

Nature, 1992
The crystal structure of the diphtheria toxin dimer at 2.5 A resolution reveals a Y-shaped molecule of three domains. The catalytic domain, called fragment A, is of the alpha + beta type. Fragment B actually consists of two domains. The transmembrane domain consists of nine alpha-helices, two pairs of which are unusually apolar and may participate in ...
S, Choe, M J, Bennett, G, Fujii, P M, Curmi, K A, Kantardjieff, R J, Collier, D, Eisenberg   +6 more
openaire   +3 more sources

Crystallization of diphtheria toxin

Journal of Molecular Biology, 1991
Two new crystal forms (forms III and IV) have been grown of diphtheria toxin (DT), which kills susceptible cells by catalyzing the ADP-ribosylation of elongation factor 2, thereby stopping protein synthesis. Forms III and IV diffract to 2.3 A and 2.7 A resolution, respectively.
G, Fujii, S H, Choe, M J, Bennett, D, Eisenberg   +3 more
openaire   +2 more sources

Diphtheria Toxin and the Diphtheria-Toxin Receptor

2000
The discovery of diphtheria toxin from culture medium of Corynehacterium diphtheriae was one of the greatest discoveries in medical history. Since this epoch-making change in medicine, diphtheria toxin has been studied, first to prevent disease and later to understand the pathogenic mechanism at the molecular level. A number of important discoveries in
T. Umata, K. D. Sharma, E. Mekada
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The Reaction of the Rat to Diphtheria Toxin

Journal of Immunology, 1921
Zingher's method of injecting intracutaneously in guinea-pigs is described. It is shown that constant results can be obtained with the Roemer technic only if the larger guinea-pigs are used (over 400 grams).
A. Coca, Ernest F. Russell, William H. Baughman   +2 more
semanticscholar   +1 more source

Diphtheria Toxin

The Journal of Immunology, 1935
Summary Semi-synthetic medium for toxin production by C. diphtheriae is quite convenient in preparation and also economical. Toxin produced in the medium described above is as potent as that produced in the ordinary-infusion bouillon. Anatoxin prepared from this toxin does not flocculate when mixed with graded amounts of antitoxin and ...
K Ando, T Komiyama
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On the formation of diphtheria toxin in saliva byC. diphtheriae

Antonie van Leeuwenhoek, 1953
1. The iron contents of a number of saliva samples were determined. The iron contents found varied from 0.10–0.61 γ per g of saliva, while in some cases the iron quantity present was so small that it could not be determined. 2. These iron contents are of the same quantitative order as the concentrations of this element in the various ...
A, TASMAN, L, SMITH
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Diphtheria toxin (Corynebacterium diphtheriae)

1997
Abstract Diphtheria toxin is the primary virulence factor of toxigenic C. diphtheriae the etiologic agent of clinical diphtheria (Pappenheimer 1977). The structural gene for diphtheria toxin, tox, is carried by a closely related family of corynebacteriophages of which the β-phage has been the best studied (Buck et al.
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