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DIPHTHERIA TOXOID

Journal of the American Medical Association, 1934
The work here reported was done with diphtheria toxoid furnished by Dr. William H. Park, director of laboratories and research, of the department of health of New York. Its purposes were: To test the relative immunizing value of a given diphtheria toxoid, with and without the addition of alum. To find the optimum dosage as to the amount and number of
JOHN L. WHITE, EMIL A. SCHLAGETER
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Alum-Precipitation of Diphtheria Toxoid (Improvement of Diphtheria Alum-Toxoid)

The Journal of Immunology, 1936
Summary Precipitation of diphtheria-toxoid by alum depends on the pH under which the precipitate is formed. Purified toxoid requires much less amounts of alum to be precipitated than the original toxoid. One-eighth by volume of 4 per cent solution of alum seems to be sufficient for toxoid purified with calcium-phosphate to precipitate ...
K Ando, T Komiyama, K Manako
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Purification and Adsorption of Diphtheria Toxoid

Nature, 1946
THE method for purification of diphtheria toxoid, which h s been used at the State Bacteriological Laboratory of Sweden since 1943, consists of two different procedures: the so-called iso-electric precipitation with trichloracetic acid of the crude toxoid and the aluminium precipitation of the partialy purified material. The method, described brj ny in
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Ionic interfaces and diphtheria toxoid interactions

Protein Expression and Purification, 2004
We present here a systematic study on the purification of the diphtheria toxoid (Dtxd) produced at the Instituto Butantan, by adding only one step on the entire process of its production. Aliquots of 1.0 ml of Dtxd were added to an equal amount of Q-Sepharose previously equilibrated with 500 mM Tris, pH 5.0-9.0 (increments of 0.5 pH units).
Raffaela A, Campana   +4 more
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ALUM-PRECIPITATED DIPHTHERIA TOXOID

Journal of the American Medical Association, 1934
During the past few years the methods of immunization against diphtheria have been greatly improved. Safe immunizing agents have been produced which contain a large amount of specific antigen, so that it is now possible to bring about a reversal in the Schick reaction from positive to negative in a larger proportion of individuals in a shorter period ...
A. E. KELLER, W. S. LEATHERS
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Diphtheria Toxoid

2023
Anna M. Acosta, Melinda Wharton
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DIPHTHERIA TOXOID (DIPHTHERIA ANATOXIN-RAMON) IN INFANCY

Journal of the American Medical Association, 1931
Diphtheria toxoid (diphtheria anatoxin-Ramon) is coming into wide usage in the active immunization against diphtheria. This antigen has given uniformly good results with the production of complete immunity in a high percentage of persons. Ramon and Helie 1 state that diphtheria anatoxin was widely used in the active immunization against diphtheria in ...
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RAPIDITY OF IMMUNIZATION WITH DIPHTHERIA TOXOID

Archives of Pediatrics & Adolescent Medicine, 1930
In a previous report, 1 we submitted our results with the use of diphtheria toxoid, concluding that this material has a high immunizing value, and that, by virtue of certain important advantages that it possesses, it recommends itself as an ideal agent in vaccination against diphtheria.
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