Results 1 to 10 of about 6,965 (156)
Challenging diagnoses of tetraploidy/diploidy and trisomy 12: utility of first-tier prenatal testing methods [PDF]
Frontiers in Genetics, 2023 Introduction: Chromosome mosaicism and low-grade mosaicism present a challenge for diagnosis in the era of SNP array and NGS. Tetraploidy is a rare numerical chromosomal abnormality characterized by the presence of four copies of each chromosome.
Irina Ioana Iordanescu +11 more
doaj +2 more sources
When Hymenopteran Males Reinvented Diploidy [PDF]
Current Biology, 2005 In most plants and animals, a consistent relationship exists between the DNA content of a cell and its metabolic activity. The male-haploid sex determination of Hymenoptera and other arthropods may therefore impose a particular selective pressure upon males, which must evolve adaptations to cope with a genomic DNA reduced by half compared with that of ...
Yves Roisin +2 more
exaly +5 more sources
Horizontal gene transfer and diploidy illuminate evolution and stress adaptation in oleaginous Scenedesmaceae (Chlorophyta) [PDF]
Nature CommunicationsOleaginous microalgae combine high lipid content with the ability to grow under diverse environmental conditions, the oleaginous species of family Scenedesmaceae (Sphaeropleales, Chlorophyta) having emerged as a promising source for biofuels ...
Linzhou Li +17 more
doaj +2 more sources
Recombination and the evolution of diploidy. [PDF]
Genetics, 1992 Abstract With two copies of every gene, a diploid organism is able to mask recessive deleterious mutations. In this paper we present the analysis of a two-locus model designed to determine when the masking of deleterious alleles favors the evolution of a dominant diploid phase in organisms that alternate between haploid and diploid ...
D B Goldstein, S P Otto
exaly +3 more sources
Genomic convergence toward diploidy in Saccharomyces cerevisiae. [PDF]
PLoS Genetics, 2006 Genome size, a fundamental aspect of any organism, is subject to a variety of mutational and selection pressures. We investigated genome size evolution in haploid, diploid, and tetraploid initially isogenic lines of the yeast Saccharomyces cerevisiae ...
Aleeza C Gerstein +3 more
doaj +4 more sources
Calcium Homeostasis Is Involved in the Modulation of Gene Expression by MSL2 in Imbalanced Genomes [PDF]
CellsAneuploidy is highly detrimental to organisms due to genomic imbalance. However, the influence of parental unbalanced genome conditions on gene expression of their offspring remains unclear, particularly in animals.
Ruixue Wang +5 more
doaj +2 more sources
Diploidy confers genomic instability in Schizosaccharomyces pombe. [PDF]
GeneticsAbstract Whole genome duplication, or polyploidy, has been implicated in driving genome instability and tumorigenesis. Recent studies suggest that polyploidy in tumors promotes cancer genome evolution, progression, and chemoresistance resulting in worse prognosis of survival.
Park JM, Pinski DF, Forsburg SL.
europepmc +4 more sources
Somatic mutation favors the evolution of diploidy. [PDF]
Genetics, 1995 Abstract Explanation of diploidy have focused on advantages gained from masking deleterious mutations that are inherited. Recent theory has shown that these explanations are flawed. Indeed, we still lack any satisfactory explanation of diploidy in species that are asexual or that recombine only rarely. Here I consider a possibility first
H A Orr
exaly +3 more sources
Does diploidy increase the rate of adaptation? [PDF]
Genetics, 1994 Abstract Explanations of the evolution of diploidy have focused on the advantages gained from masking deleterious alleles. Recent theory has shown, however, that masking does not always provide an advantage to diploidy and would never favor diploidy in predominantly asexual organisms.
H A Orr, S P Otto
exaly +3 more sources
Ветеринария сегодня, 2023 The main advantage of transformed cell lines as compared to primary ones is that they allow generation of the stable material suitable for long-term research and practical use.
B. L. Manin +3 more
doaj +1 more source