Results 11 to 20 of about 8,207 (204)

Evolutionary route to diploidy and sex [PDF]

Proceedings of the National Academy of Sciences, 2001
By using a bit-string model of evolution, we find a successful route to diploidy and sex in simple organisms. Allowing the sexually reproducing diploid individuals to also perform mitosis, as they do in a haploid-diploid cycle, leads to the complete ...
Erzan, A, Sevim, V, Tuzel, E
core   +8 more sources

Diploidy within a Haploid Genus of Entomopathogenic Fungi [PDF]

Genome Biology and Evolution, 2021
Fungi in the genus Metarhizium are soil-borne plant–root endophytes and rhizosphere colonizers, but also potent insect pathogens with highly variable host ranges. These ascomycete fungi are predominantly asexually reproducing and ancestrally haploid, but
Salgado, João Felipe Moreira, Stajich, Jason E, Nielsen, Knud Nor, de Fine Licht, Henrik Hjarvard, Kristensen, Thea, Stajich, Jason E., De Fine Licht, Henrik H, Natsopoulou, Myrsini Eirini, Knud Nor Nielsen, Henrik H De Fine Licht, Jason E Stajich, Thea Kristensen, Myrsini Eirini Natsopoulou, João Felipe Moreira Salgado, Henrik H. De Fine Licht   +14 more
core   +6 more sources

A computational model of evolution: haploidy versus diploidy [PDF]

Comput. Artif. Intell., 1999
In this paper, the study of diploidy is introduced like and important mechanism for memory reinforcement in artificial environments where adaptation is very important.
Molina López, José Manuel, Berlanga de Jesús, Antonio, Sanchis de Miguel, María Araceli, Isasi, Pedro, Isasi Viñuela, Pedro   +4 more
core   +7 more sources

Mutation accumulation may only be a minor force in shaping life-history traits, even when reproduction is sexual. [PDF]

PLoS ONE, 2012
In a previous theoretical study we investigated whether adaptive or non-adaptive processes are more important in the evolution of senescence. We built a model that combined both processes and found that mutation accumulation is important only at those ...
Maciej Jan Dańko, Jan Kozłowski
doaj   +3 more sources

Onset of quiescence following p53 mediated down-regulation of H2AX in normal cells.

PLoS ONE, 2011
Normal cells, both in vivo and in vitro, become quiescent after serial cell proliferation. During this process, cells can develop immortality with genomic instability, although the mechanisms by which this is regulated are unclear.
Yuko Atsumi, Hiroaki Fujimori, Hirokazu Fukuda, Aki Inase, Keitaro Shinohe, Yoshiko Yoshioka, Mima Shikanai, Yosuke Ichijima, Junya Unno, Shuki Mizutani, Naoto Tsuchiya, Yoshitaka Hippo, Hitoshi Nakagama, Mitsuko Masutani, Hirobumi Teraoka, Ken-ichi Yoshioka   +15 more
doaj   +2 more sources

Can Repeated Reductive Genome Evolution Across Archaeplastida Explain Volatility in Traits? [PDF]

Adv Genet (Hoboken)
Genome evolution in Archaeplastida is often framed around gene gains and increasing complexity. Yet ancestral reconstructions reveal recurrent genome contraction, with ancestors frequently harboring larger gene repertoires than descendants. Across red algae, land‐plant ancestry, and embryophyte diversification, repeated expansion and reduction cycles ...
Kunz CF, Baştürk MN, de Vries J, Chen H.   +3 more
europepmc   +2 more sources

The cold case of state transition 7 (stt7) mutants of Chlamydomonas reinhardtii, solved by whole-genome sequencing. [PDF]

New Phytol
Long‐read whole‐genome sequencing revealed extensive chromosomal rearrangements and aneuploidy in a widely used Chlamydomonas reinhardtii stt7‐1 mutant. The STT7 gene (shown in red) was found to be split between two rearranged chromosomes, providing a molecular explanation for the long‐standing failure of this mutant in genetic crosses.
Bujaldon S, Burlacot A, Chaux F, Wollman FA.   +3 more
europepmc   +2 more sources

The evolution of haploidy and diploidy [PDF]

Current Biology, 2008
It is remarkable that one of the most fundamental features of an organism — its ploidy level — is so variable among taxa, with life cycles running the entire gamut from complete haploid dominance to complete diploid dominance. Theoretical studies have clarified many important genetic advantages to haploidy (for example, lower mutation load, more rapid ...
Otto, Sarah P., Gerstein, Aleeza C.
openaire   +2 more sources

Digital PCR for Detecting Loss of BAP1 and MTAP in Pleural Fluids of Mesothelioma Patients: Perspectives in the Diagnosis. [PDF]

Pathol Int
BAP1/MTAP gene losses were measured with dPCR in solid tumor biopsies (STBs) and in supernatant of pleural fluids (SPFs) of mesothelioma patients. Results were compared with immunohistochemistry (IHC) carried out in STBs. A good concordance between the methods was found and, interestingly, their combination seems to ameliorate the identification of PM ...
Rosini G, Alì G, Bruno R, Cipollini M, Foddis R, Celi A, Silvestri R, Rea F, Aprile V, Lucchi M, Gemignani F, Landi S.   +11 more
europepmc   +2 more sources

When Hymenopteran Males Reinvented Diploidy [PDF]

Current Biology, 2005
In most plants and animals, a consistent relationship exists between the DNA content of a cell and its metabolic activity. The male-haploid sex determination of Hymenoptera and other arthropods may therefore impose a particular selective pressure upon males, which must evolve adaptations to cope with a genomic DNA reduced by half compared with that of ...
Aron, Serge, de Menten de Horne, Ludivine, Van Bockstaele, Dirk R., Blank, S.M., Roisin, Yves   +4 more
openaire   +4 more sources