Results 11 to 20 of about 6,845 (132)
X-Linked Intellectual Developmental Disorder-93 Caused by BRWD3 Mutation in Females: A Case Report and Literature Review. [PDF]
Mol Genet Genomic MedA case of MRX93 in a 1‐year‐and‐3‐month‐old girl was reported, in whom a heterozygous deletion from exon 21 to exon 30 in the BRWD3 gene occurred. We conducted a literature review to explore the clinical phenotypes and genetic characteristics of MRX93 in females. ABSTRACT Objective To report the clinical manifestations and genetic diagnosis of a female
Xiu Y, Zhang Y, Jiao Y, Wang W, Hu Y.
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Mutation accumulation may only be a minor force in shaping life-history traits, even when reproduction is sexual. [PDF]
PLoS ONE, 2012 In a previous theoretical study we investigated whether adaptive or non-adaptive processes are more important in the evolution of senescence. We built a model that combined both processes and found that mutation accumulation is important only at those ...
Maciej Jan Dańko, Jan Kozłowski
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Target Capture Sequencing Provides Insights Into Hybridogenetic Water Frogs. [PDF]
Ecol EvolThe genomics of European frogs of the genus Pelophylax are intriguing due to their propensity to hybridise, the prevalence of polyploidy, and the unusual hemiclonal hybridogenetic complexes formed in many populations. This study examines the use of target capture sequencing using the Frog Cap bait set to investigate these complex systems.
van Veldhuijzen L +5 more
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Journal of Pharmacy and Bioallied Sciences, 2020 Background: Methods to analyze progression of carcinogenesis and stage of cancer are vital nowadays due to the high prevalence of these lesions. DNA ploidy analysis is one such important method in early diagnosis and improving prognosis.
Surekha Velidandla +5 more
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Effects of ploidy and recombination on evolution of robustness in a model of the segment polarity network. [PDF]
PLoS Computational Biology, 2009 Many genetic networks are astonishingly robust to quantitative variation, allowing these networks to continue functioning in the face of mutation and environmental perturbation. However, the evolution of such robustness remains poorly understood for real
Kerry J Kim, Vilaiwan M Fernandes
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Ancient evolutionary trade-offs between yeast ploidy states. [PDF]
PLoS Genetics, 2013 The number of chromosome sets contained within the nucleus of eukaryotic organisms is a fundamental yet evolutionarily poorly characterized genetic variable of life.
Enikö Zörgö +8 more
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mBio, 2017 Bacteria regulate chromosome replication and segregation tightly with cell division to ensure faithful segregation of DNA to daughter generations. The underlying mechanisms have been addressed in several model species.
Kati Böhm +5 more
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Anales del Jardín Botánico de Madrid, 2009 A karyological analysis has been conducted of all five native Macaronesian Festuca grasses belonging to fine-leaved F. subg. Festuca sect. Aulaxyper and broad-leaved F. subg. Drymanthele sect. Phaeochloa Loliinae lineages.
Miguel Menezes de Sequeira +4 more
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Cryptic fitness advantage: diploids invade haploid populations despite lacking any apparent advantage as measured by standard fitness assays. [PDF]
PLoS ONE, 2011 Ploidy varies tremendously within and between species, yet the factors that influence when or why ploidy variants are adaptive remains poorly understood.
Aleeza C Gerstein, Sarah P Otto
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Onset of quiescence following p53 mediated down-regulation of H2AX in normal cells.
PLoS ONE, 2011 Normal cells, both in vivo and in vitro, become quiescent after serial cell proliferation. During this process, cells can develop immortality with genomic instability, although the mechanisms by which this is regulated are unclear.
Yuko Atsumi +15 more
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