Results 11 to 20 of about 13,896 (236)
A computational model of evolution: haploidy versus diploidy [PDF]
COMPUTING AND INFORMATICS, 1999 In this paper, the study of diploidy is introduced like and important mechanism for memory reinforcement in artificial environments where adaptation is very important.
Berlanga de Jesús, Antonio +3 more
core +5 more sources
The evolution of haploidy and diploidy. [PDF]
Current Biology, 2008 It is remarkable that one of the most fundamental features of an organism — its ploidy level — is so variable among taxa, with life cycles running the entire gamut from complete haploid dominance to complete diploid dominance. Theoretical studies have clarified many important genetic advantages to haploidy (for example, lower mutation load, more rapid ...
S. Otto, A. Gerstein
semanticscholar +3 more sources
Diploidy confers genomic instability in Schizosaccharomyces pombe. [PDF]
GeneticsAbstractWhole genome duplication, or polyploidy, has been implicated in driving genome instability and tumorigenesis. Recent studies suggest that polyploidy in tumors promotes cancer genome evolution, progression, and chemoresistance resulting in worse prognosis of survival.
Park JM, Pinski DF, Forsburg SL.
europepmc +4 more sources
Molecular Genetics & Genomic Medicine, 2021 Background In gestational trophoblastic disease, the prognosis is related to the genetic constitution. In some cases, taking a biopsy is contraindicated. Methods In a pregnant woman, ultrasound scanning suggested hydatidiform mole.
Lone Sunde +7 more
doaj +1 more source
When Hymenopteran Males Reinvented Diploidy [PDF]
Current Biology, 2005 In most plants and animals, a consistent relationship exists between the DNA content of a cell and its metabolic activity. The male-haploid sex determination of Hymenoptera and other arthropods may therefore impose a particular selective pressure upon males, which must evolve adaptations to cope with a genomic DNA reduced by half compared with that of ...
Aron, Serge +4 more
openaire +4 more sources
Mutation accumulation may only be a minor force in shaping life-history traits, even when reproduction is sexual. [PDF]
PLoS ONE, 2012 In a previous theoretical study we investigated whether adaptive or non-adaptive processes are more important in the evolution of senescence. We built a model that combined both processes and found that mutation accumulation is important only at those ...
Maciej Jan Dańko, Jan Kozłowski
doaj +1 more source
Evolutionary route to diploidy and sex [PDF]
Proceedings of the National Academy of Sciences, 2001 By using a bit-string model of evolution, we find a successful route to diploidy and sex in simple organisms. Allowing the sexually reproducing diploid individuals to also perform mitosis, as they do in a haploid-diploid cycle, leads to the complete takeover of the population by sexual diploids.
Tuzel, E, Sevim, V, Erzan, A
openaire +5 more sources
Journal of Pharmacy and Bioallied Sciences, 2020 Background: Methods to analyze progression of carcinogenesis and stage of cancer are vital nowadays due to the high prevalence of these lesions. DNA ploidy analysis is one such important method in early diagnosis and improving prognosis.
Surekha Velidandla +5 more
doaj +1 more source
Effects of ploidy and recombination on evolution of robustness in a model of the segment polarity network. [PDF]
PLoS Computational Biology, 2009 Many genetic networks are astonishingly robust to quantitative variation, allowing these networks to continue functioning in the face of mutation and environmental perturbation. However, the evolution of such robustness remains poorly understood for real
Kerry J Kim, Vilaiwan M Fernandes
doaj +1 more source
Stem Cells and Development, 2019 A major objective of modern biomedical research aims to promote tissue self-regeneration after injury, obviating the need for whole organ transplantation and avoiding mortality due to organ failure.
Michaela Patterson, Samantha K. Swift
semanticscholar +1 more source