Results 51 to 60 of about 13,896 (236)

Muller's ratchet and mutational meltdowns [PDF]

open access: yes, 1993
We extend our earlier work on the role of deleterious mutations in the extinction of obligately asexual populations. First, we develop analytical models for mutation accumulation that obviate the need for time-consuming computer simulations in certain ...
Bürger, Reinhard   +2 more
core   +1 more source

Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot.

open access: yesGenes & Development, 1994
The Drosophila escargot (esg) gene encodes a C2-H2-type zinc finger protein that is expressed in the imaginal discs and histoblasts. In some esg mutants, the abdominal histoblasts become polyploid.
N. Fuse, S. Hirose, S. Hayashi
semanticscholar   +1 more source

Current advances in haploid stem cells

open access: yesProtein & Cell, 2019
Diploidy is the typical genomic mode in all mammals. Haploid stem cells are artificial cell lines experimentally derived in vitro in the form of different types of stem cells, which combine the characteristics of haploidy with a broad developmental ...
Tongtong Cui, Zhikun Li, Qi Zhou, Wei Li
doaj   +1 more source

Effects of an Unusual Poison Identify a Lifespan Role for Topoisomerase 2 in Saccharomyces Cerevisiae [PDF]

open access: yes, 2017
A progressive loss of genome maintenance has been implicated as both a cause and consequence of aging. Here we present evidence supporting the hypothesis that an age-associated decay in genome maintenance promotes aging in Saccharomyces cerevisiae (yeast)
Baxter, Bonnie   +13 more
core   +2 more sources

Potential Drivers of Successful Biocontrol: A Perspective on Parasitoids

open access: yesNew Zealand Journal of Zoology, Volume 53, Issue 1, March 2026.
Parasitoids are central to classical biological control, yet predicting their long‐term effectiveness post release remains challenging. In Aotearoa New Zealand, three Microctonus (Hymenoptera: Braconidae) species have been used against pest weevils, but key aspects of their biology remain poorly understood.
Meeran Hussain   +3 more
wiley   +1 more source

Molecular and immunohistochemical characteristics of complete hydatidiform moles

open access: yesBalkan Journal of Medical Genetics, 2017
Molar pregnancy is a gestational trophoblastic disease that belongs to the category of precancerous lesions. On the other end of the spectrum are gestational trophoblastic neoplasms such as invasive mole, choriocarcinoma, placental site trophoblastic ...
Kubelka-Sabit KB   +6 more
doaj   +1 more source

Experimental Evolution Reveals Interplay between Sch9 and Polyploid Stability in Yeast. [PDF]

open access: yesPLoS Genetics, 2016
Polyploidization has crucial impacts on the evolution of different eukaryotic lineages including fungi, plants and animals. Recent genome data suggest that, for many polyploidization events, all duplicated chromosomes are maintained and genome ...
Yi-Jin Lu, Krishna B S Swamy, Jun-Yi Leu
doaj   +1 more source

Autopolyploidization‐Induced Chromatin Remodeling Regulates Leaf Size Variation in Brassica rapa

open access: yesAdvanced Science, Volume 13, Issue 9, 13 February 2026.
This study demonstrates that monoploid, diploid, and autotetraploid Brassica rapa lines derived from the same genome exhibit distinct leaf morphology. Ploidy changes remodel chromatin accessibility and histone modifications to regulate gene expression, while key transcription factors BrGRF13 and BrARF11 control leaf size and polarity, driving ...
Haoyuan Dong   +17 more
wiley   +1 more source

Induction of gynogenesis by heterogenous sperm and cold shock treatment in Epinephelus fuscoguttatus

open access: yesReproduction and Breeding, 2021
Gynogenesis is a chromosome set manipulation technique to accelerate inbred lines used for genomics analysis and genetic breeding. Groupers are hermaphroditic fish whereby they sexually mature as females and subsequently change sex to male. Production of
Weiwei Zhang   +10 more
doaj   +1 more source

Isoenzyme electrophoresis of 30 isolates of Giardia from humans and felines [PDF]

open access: yes, 1988
Thirty isolates of Giardia duodenalis from humans and felines were compared by isoenzyme electrophoresis. Using 10 enzyme systems, 13 different zymodemes were distinguished. The majority of zymodemes could be divided into two groups: one group comprising
Lymbery, A.J.   +2 more
core   +2 more sources

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