Results 21 to 30 of about 23,468 (210)

Discovery of Dipyridamole Analogues with Enhanced Metabolic Stability for the Treatment of Idiopathic Pulmonary Fibrosis

Molecules, 2022
Dipyridamole, apart from its well-known antiplatelet and phosphodiesterase inhibitory activities, is a promising old drug for the treatment of pulmonary fibrosis.
Meng-Xing Huang, Yan-Quan Chen, Run-Duo Liu, Yue Huang, Chen Zhang   +4 more
doaj   +1 more source

Tenofovir Causes Bone Loss via Decreased Bone Formation and Increased Bone Resorption, Which Can Be Counteracted by Dipyridamole in Mice

Journal of Bone and Mineral Research, 2019
Osteopenia and fragility fractures have been associated with human immunodeficiency virus (HIV) infection. Tenofovir, a common antiviral in HIV treatment, also leads to increases in bone catabolism markers and decreased BMD in children and young adults ...
F. Conesa-Buendía, Patricia Llamas‐Granda, A. Larrañaga-Vera, T. Wilder, R. Largo, G. Herrero-Beaumont, B. Cronstein, A. Mediero   +7 more
semanticscholar   +1 more source

Current and future use of dipyridamole in patients with COVID-19

Качественная клиническая практика, 2020
Current use of dipyridamole in COVID-19 is mainly based on its antithrombotic activity, since there is no robust clinical effectiveness data. The decision to use dipyridamole in COVID-19 should be individualized, considering the experimental nature of ...
I. S. Burashnikova, V. M. Tsvetov, K. B. Mirzaev, D. A. Sychev   +3 more
doaj   +1 more source

Bone Tissue Engineering in the Growing Calvaria Using Dipyridamole-Coated, Three-Dimensionally–Printed Bioceramic Scaffolds: Construct Optimization and Effects on Cranial Suture Patency

Plastic and Reconstructive Surgery, 2019
Background: Three-dimensionally–printed bioceramic scaffolds composed of β-tricalcium phosphate delivering the osteogenic agent dipyridamole can heal critically sized calvarial defects in skeletally mature translational models.
S. Maliha, Christopher D Lopez, P. Coelho, L. Witek, Madison E. Cox, Alan Meskin, Sejndi Rusi, A. Torroni, B. Cronstein, R. Flores   +9 more
semanticscholar   +1 more source

Dipyridamole Augments 3D Printed Bioactive Ceramic Scaffolds to Regenerate Craniofacial Bone

Plastic and Reconstructive Surgery, 2019
Background: Autologous bone grafts remain a standard of care for the reconstruction of large bony defects, but limitations persist. The authors explored the bone regenerative capacity of customized, three-dimensionally printed bioactive ceramic scaffolds
Christopher D Lopez, J. Diaz-Siso, L. Witek, Jonathan M. Bekisz, L. Gil, B. Cronstein, Roberto L. Flores, A. Torroni, Eduardo D. Rodriguez, P. Coelho   +9 more
semanticscholar   +1 more source

Changes of electrocardiogram and hemodynamics in response to dipyridamole: In vivo comparative analyses using anesthetized beagle dogs and microminipigs

Journal of Pharmacological Sciences, 2018
Microminipigs are expected as a novel animal model for cardiovascular pharmacological experiments. Since inherent vulnerability of coronary circulation of microminipigs has not been characterized, we performed dipyridamole-stress test to both ...
Kentaro Ando, Akira Takahara, Yuji Nakamura, Takeshi Wada, Koki Chiba, Ai Goto, Nur Jaharat Lubna, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Kiyotaka Hoshiai, Yasuki Akie, Atsuhiko T. Naito, Atsushi Sugiyama   +12 more
doaj   +1 more source

Dipyridamole enhances osteogenesis of three-dimensionally printed bioactive ceramic scaffolds in calvarial defects

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2017
Summary Purpose The objective of this study was to test the osteogenic capacity of dipyridamole-loaded, three-dimensionally printed, bioactive ceramic (3DPBC) scaffolds using a translational, skeletally mature, large-animal calvarial defect model ...
Jonathan M. Bekisz, R. Flores, L. Witek, Christopher D Lopez, C. Runyan, A. Torroni, B. Cronstein, P. Coelho   +7 more
semanticscholar   +1 more source

Nucleoside Transport Inhibition by Dipyridamole Prevents Angiogenesis Impairment by Homocysteine and Adenosine

Journal of Pharmacy & Pharmaceutical Sciences, 2015
Purpose: Adenosine plays an important role in the pathogenesis of homocysteine-associated vascular complications. Methods: This study examined the effects of dipyridamole, an inhibitor for nucleoside transport, on impaired angiogenic processes caused by ...
Antony Kam, Valentina Razmovski-Naumovski, Xian Zhou, John Troung, Kelvin Chan   +4 more
doaj   +1 more source

Dipyridamole-induced adverse effects in myocardial perfusion scans: Dynamic evaluation

International Journal of Cardiology: Heart & Vasculature, 2017
Aim and Background: Dipyridamole-induced stress myocardial perfusion scans (MPS) has been widely used for management of coronary artery disease. The adverse effects of dipyridamole and other stress agents have been evaluated.
Sin-Di Lee, Wei-Chun Huang, Nan-Jing Peng, Chin Hu   +3 more
doaj   +1 more source

Determination of Dipyridamole Using a MIP-Modified Disposable Pencil Graphite Electrode

Chemosensors, 2023
A new method for the determination of the antiplatelet drug dipyridamole (DIP) in pharmaceuticals using a molecularly imprinted polymer (MIP)-modified pencil graphite electrode (PGE) is proposed.
Daniel Preda, Maria Lorena Jinga, Iulia Gabriela David, Gabriel Lucian Radu   +3 more
doaj   +1 more source