Results 41 to 50 of about 460 (120)

Head-to-head comparison of dipyridamole, dobutamine and pacing stress echocardiography for the detection of myocardial ischemia in an animal model of coronary artery stenosis

Brazilian Journal of Medical and Biological Research, 2001
To compare the sensitivity of dipyridamole, dobutamine and pacing stress echocardiography for the detection of myocardial ischemia we produced a physiologically significant stenosis in the left circumflex artery of 14 open-chest dogs (range: 50 to 89 ...
A. Schmidt, O.C. de Almeida-Filho, E.M. Ayres-Neto, J.J. Carneiro, J.A. Marin-Neto, B.C. Maciel   +5 more
doaj   +1 more source

Caffeine and Headache: Exploring the Multifaceted Relationship

Brain and Behavior, Volume 16, Issue 6, June 2026.
ABSTRACT Purpose To explore the multifaceted relationship between caffeine and headache disorders, focusing on its dual role as both an analgesic and a potential trigger and to summarize the mechanisms underlying its anti‐nociceptive effects. Method This narrative review synthesizes evidence from experimental, clinical, and epidemiological studies on ...
Mona Hussein, Amr Hassan, Salsabil Abo Al‐Azayem, Janu Thuraiaiyah, Henrik Winther Schytz, Anter Mothenna Abdullah Nasser, Rehab Magdy   +6 more
wiley   +1 more source

Comparison of exercise, dobutamine-atropine and dipyridamole-atropine stress echocardiography in detecting coronary artery disease

Cardiovascular Ultrasound, 2006
Background Dipyridamole and dobutamine stress echocardiography testing are most widely utilized, but their sensitivity remained suboptimal in comparison to routine exercise stress echocardiography.
Petrasinovic Zorica, Saponjski Jovica, Stankovic Goran, Stojkovic Sinisa, Nedeljkovic Milan, Stepanovic Jelena, Djordjevic-Dikic Ana, Beleslin Branko, Ostojic Miodrag, Nedeljkovic Ivana, Giga Vojislav, Mitrovic Predrag   +11 more
doaj   +1 more source

Metal‐dependent regulated cell death: Molecular architecture and translational frontiers

iMeta, Volume 5, Issue 3, June 2026.
Intracellular metal dyshomeostasis orchestrates distinct regulated cell death programs, including iron‐driven ferroptosis, copper‐mediated cuproptosis, calcicoptosis, newly designated zincoptosis, mnoptosis, and coptosis. This review systematically delineates their molecular architectures—spanning from Sorafenib‐induced lipid peroxidation and ...
Haoliang Hu, Zhe Chen, Yaqi Li, Jiayi Peng, Jiangang Cao, Hong Zhou, Mengqi Wang, Yuejia Du, Hailin Wu, Huiqin Zhao, Shifang Huang, Dianmei Yu, Meiqing Liu, Olga V. Shevchenko, Natalia Yu. Matveeva, Yiyuan Yang, Kerui Huang, Deguan Lv, Junxia Min, Linxi Chen, Fudi Wang   +20 more
wiley   +1 more source

Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics

MedComm, Volume 7, Issue 6, June 2026.
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou, Sheng He, Lili He, Kun Liu, Wen Tang, Deming Wang, Jing Gui, Zhiying Zeng, Yan Wang, Wenjie Liu, Ren Jing   +10 more
wiley   +1 more source

Dysregulated Lipid Metabolism in Hepatocellular Carcinoma: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Dysregulated lipid metabolism facilitates hepatocellular carcinoma (HCC) development, progression, immunosuppressive tumor microenvironment (TME) formation, and therapeutic resistance. Notably, the patterns of lipid metabolism vary significantly among different types of HCC driven by various etiologies.
Yi Yi, Xi Liu, Xi Zhang, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source

Evaluating the Educational Value of Artificial Intelligence in Pharmacotherapy Education

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Final‐year medical students frequently make prescribing errors, partly because they have had insufficient training in therapeutic reasoning. Students need to understand the underlying rationale behind a drug choice in order to subsequently apply that knowledge critically and independently.
Mariëlle G. Hartjes, Michiel J. Bakkum, Milan C. Richir, Michiel A. van Agtmael, Jelle Tichelaar   +4 more
wiley   +1 more source

Dipyridamole reduces penile apoptosis in a rat model of post-prostatectomy erectile dysfunction

International Brazilian Journal of Urology
Purpose: Despite the nerve-sparing technique, many patients suffer from erectile dysfunction after radical prostatectomy (RP) due to cavernous nerve injury. The aim of this study was to evaluate dipyridamole as a potential treatment agent of post-radical
Omer Kutlu, Ersagun Karaguzel, Ali Ertan Okatan, Ahmet Mentese, Esin Yulug, Ilke Onur Kazaz, Selcuk Kutlu, Eyup Dil, Huseyin Eren, Ahmet Alver   +9 more
doaj   +1 more source

Sex‐Specific Associations of Inflammatory Biomarkers With All‐Cause and Cardiovascular Mortality Across Glycaemic Status: A Prospective UK Biobank Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4728-4740, June 2026.
ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang, Menghan Li, Manrong Xu, Yun Shen, Lianxi Li, Gang Hu   +5 more
wiley   +1 more source

Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury

Advanced Science
Ferroptosis is a newly identified cell death triggered by iron‐induced lipid peroxidation. Numerous studies reveal that ferroptosis participates in multiple types of tissue injury including ischaemia–reperfusion (I/R) injury and doxorubicin (Dox)‐induced
Xiao Zhuang, Shuang Shi, Shuo Liu, Yaqiong Jiao, Bin Huang, Yinghong Yang, Li Yang, Xinquan Yang, Hui Wang, Chunhui Liang, Dandan Song, Huaxiang Yu, Dan Zou, Qi Sun, Shu Yang, Chengqian Yin, Jian Li, Yiming Liu, Junxia Min, Fudi Wang, Yong Nian, Lutao Du, Bo Chu   +22 more
doaj   +1 more source