Results 51 to 60 of about 460 (120)

XIAP Deficiency Impairs Colonic Tuft Cell Development and Predisposes to Crohn's Disease

MedComm, Volume 7, Issue 5, May 2026.
XIAP deficiency leads to impaired colonic tuft cells development and JAK–‐STAT pathway hyperactivation in CD patients and mice. Mechanically, XIAP regulates tuft cells development through Wnt–‐TLE4/TCF–‐ASCL2 signaling. Tuft cells deficiency predisposes XIAP‑‐deficient CD patients or Xiap−/−‐/‐ mice to hazardous microbial effects, driving colonic ...
Rongli Fang, Wei Wang, Li Zhang, Jiwei Huang, Lei Huang, Huibo Wu, Yuyin Qi, Lili Li, Liren Tan, Min Zhang, Jianheng Zhu, Xiang Peng, Kanghua Zhong, Ming Zou, Xi Yang, Qiuhua Wang, Changjun Nie, Chaorui Tang, Ning Tang, Lanlan Geng, Hanhan Chen, James E. Vince, Hirokazu Kanegane, Xiaodong Zhao, Huifang Xian, Wenhao Zhou, Min Zhi, Yuxia Zhang, Zhanghua Chen   +28 more
wiley   +1 more source

Japanese Clinical Practice Guidelines for Vascular Tumors, Vascular Malformations, Lymphatic Malformations, and Lymphangiomatosis 2022

The Journal of Dermatology, Volume 53, Issue 5, Page e257-e356, May 2026.
ABSTRACT The objective was to prepare guidelines to perform the current optimum treatment by organizing effective and efficient treatments of hemangiomas and vascular malformations, confirming the safety, and systematizing treatment, employing evidence‐based medicine techniques and aimed at improvement of the outcomes.
Yoshiaki Kinoshita, Kosuke Ishikawa, Sadanori Akita, Katsuyoshi Koh, Satoru Sasaki, Masatoshi Jinnin, Hidefumi Mimura, Keigo Osuga, Michio Ozeki, Michiko Nagahama, Akihiro Fujino, Yoko Aoki, Akiko Asai, Noriko Aramaki‐Hattori, Ryohei Ishiura, Masanori Inoue, Yuki Iwashina, Takafumi Ohshiro, Keiko Ogawa, Mine Ozaki, Junko Ochi, Shiro Onozawa, Motoi Kato, Takahide Kaneko, Tamihiro Kawakami, Akira Kitagawa, Masakazu Kurita, Yoshihiro Kuwano, Taro Kono, Shien Seike, Shinsuke Takagi, Nobuyuki Takakura, Takao Tachibana, Shuichi Tanoue, Kumiko Chuman, Hiroki Nakaoka, Yasuhiro Nakamura, Fumio Nagai, Yasunari Niimi, Shunsuke Nosaka, Taiki Nozaki, Tadashi Nomura, Kazuki Hashimoto, Ayato Hayashi, Satoshi Hirakawa, Takeshi Hirabayashi, Taizo Furukawa, Hiroshi Furukawa, Yumiko Hori, Takanobu Maekawa, Kentaro Matsuoka, Hideki Mori, Eiichi Morii, Akira Morimoto, Yuta Moriwaki, Shunsuke Yuzuriha, Naoaki Rikihisa, Munezumi Fujita, Yasuyuki Yamahana, Kyoichi Deie, Asami Tozawa, Daisuke Hasegawa, Akira Higashiyama, Daisuke Maeda, Sachiko Asayama, Yuhki Arai, Yohei Iwata, Mayu Uka, Hidehito Usui, Mizuki Uchiyama, Saori Endo, Hideki Endo, Rintaro Ono, Naoya Oshima, Toshihiro Otsuka, Kuniaki Ohara, Shinji Kagami, Tomo Kakihara, Mototoshi Kato, Hiroki Kanamori, Masafumi Kamata, Ami Kawaguchi, Akiko Kishi, Hiroshi Kitagawa, Kiyokazu Kim, Tamotsu Kobayashi, Takeshi Saito, Yusuke Shikano, Shuichi Shimada, Keisuke Suzuki, Masataka Takahashi, Shohei Takami, Reiko Takeda, Aya Tanaka, Kaishu Tanaka, Satoru Tamura, Masashi Tamura, Kanako Danno, Kenji Tsuboi, Yuta Nakajima, Ryo Nakatani, Miho Noguchi, Akifumi Nozawa, Naoki Hashizume, Masashi Hayakawa, Daichi Hayashi, Takaya Fukumoto, Mamoru Honda, Norifumi Matsuda, Hayato Maruguchi, Naoki Murakami, Kiichiro Yaguchi, Shiho Yasue, Hiroki Yoshihara, Rika Yoshimatsu, Kiyohito Yamamoto, Shinji Wada   +116 more
wiley   +1 more source

Phosphodiesterase Inhibition and Immunotropic Activity of Dipyridamole Dynamic Derivatives

Current Issues in Molecular Biology
Introduction. Many pharmacological properties of dipyridamole (DIP) are associated with its ability to inhibit phosphodiesterases (PDEs). Actually, DIP has interesting properties like antiviral for influenza, SARS-2 COVID-19, and herpesviruses.
Artur Martynov, Boris Farber, Alexander Katz   +2 more
doaj   +1 more source

Triple versus guideline antiplatelet therapy to prevent recurrence after acute ischaemic stroke or transient ischaemic attack: the TARDIS RCT

Health Technology Assessment, 2018
Background: Two antiplatelet agents are better than one for preventing recurrent stroke after acute ischaemic stroke or transient ischaemic attack (TIA).
Philip M Bath, Lisa J Woodhouse, Jason P Appleton, Maia Beridze, Hanne Christensen, Robert A Dineen, Katie Flaherty, Lelia Duley, Timothy J England, Diane Havard, Stan Heptinstall, Marilyn James, Chibeka Kasonde, Kailash Krishnan, Hugh S Markus, Alan A Montgomery, Stuart Pocock, Marc Randall, Annamarei Ranta, Thompson G Robinson, Polly Scutt, Graham S Venables, Nikola Sprigg   +22 more
doaj   +1 more source

Repurposing of the Cardiovascular Drug Statin for the Treatment of Cancers: Efficacy of Statin–Dipyridamole Combination Treatment in Melanoma Cell Lines

Biomedicines
Metastatic melanoma has a very poor prognosis. Statins, 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR) inhibitors, are cholesterol-lowering agents with a potential for cancer treatment.
Nanami Irie, Kana Mizoguchi, Tomoko Warita, Mirai Nakano, Kasuga Sasaki, Jiro Tashiro, Tomohiro Osaki, Takuro Ishikawa, Zoltán N. Oltvai, Katsuhiko Warita   +9 more
doaj   +1 more source

Dipyridamole stress echocardiography combined with pair-wise bicycle stress test and transesophageal atrial stimulation in coronary heart disease diagnostics

Российский кардиологический журнал, 2005
The aim of the study was to identify and compare informative values of combined high-dose dipyridamole stress echocardiography (EchoCG) and pair bicycle stress test, or transesophageal atrial pacing (TEAP), in coronary stenosis diagnostics.
A. Yu. Vasilyev, N. N. Mikheev
doaj  

Experience of using MHT combined with dipyridamole in patients in the early postmenopause

Медицинский совет, 2019
This article presents the evaluation of efficacy of low-dose dipyridamole used to prevent thrombotic complications during menopausal therapy in women in the early postmenopause.
T. M. Sokolova, I. O. Marinkin, V. M. Кuleshov, K. Yu. Makarov   +3 more
doaj   +1 more source

Topic diagnostics of coronary pathology in coronary heart disease patients by contrast stress echocardiography with dipyridamole

Кардиоваскулярная терапия и профилактика, 2005
Aim. To assess diagnostic potential of contrast stress echocardiography (CS-EchoCG) with dipyridamole in coronary heart disease (CHD) patients. Material and methods. The study included 22 patients (mean age 56.04±1.8 years) with typical CHD clinics.
S. T. Matskeplishvili, E. U. Asymbekova, E. A. Ayazyan, V. I. Ioshina, T. V. Kavtiashvili   +4 more
doaj  

Experience in using dipyridamole in the group of pregnant women with a high risk of perinatal pathology

Медицинский совет, 2018
This article provides the evaluation results of the efficacy of low-dose dipyridamole (CurantylÒ) [1, 2] taken to prevent placental insufficiency in women in the group with a high risk of perinatal pathology and feto-maternal disease in past medical ...
T. M. Sokolova, I. O. Marinkin, V. M. Kuleshov, K. Yu. Makarov   +3 more
doaj   +1 more source

Reproductive disorders and obstetric complications in gynecological diseases [PDF]

Гинекология, 2018
This publication examines the existing risks of obstetric complications and other reproductive disorders in women with gynecological diseases. The paper also discusses the issues of the pre-school training of women with gynecological diseases, with ...
A L Unanian, I S Sidorova, A D Nikonets, L N Aminova, V A Alimov, A V Shchukina, Yu V Chushkov, D V Baburin   +7 more
doaj