Antitumor effect of dipyridamole mediated by inhibiting the interaction between platelets and tumor cells [PDF]
Discover OncologyDipyridamole is a well-known antithrombotic and a vasodilator. It is used to treat cerebrovascular and cardiovascular diseases owing to its antiplatelet effects.
Jie Xue +6 more
doaj +2 more sources
In Vitro Antioxidant Activity and Dual-Target Inhibitory Effects of Dipyridamole on α-Amylase and α-Glucosidase: Molecular Mechanisms and Molecular Dynamics Simulations [PDF]
Biomoleculesα-Amylase and α-glucosidase are complementary therapeutic targets in type 2 diabetes; simultaneous inhibition provides a dual-blockade strategy to suppress postprandial hyperglycemia.
Cong Zhao +8 more
doaj +2 more sources
Differentiating ischemic from healthy myocardium using cardiovascular magnetic resonance dipyridamole rest and stress T1 mapping [PDF]
Scientific ReportsCardiovascular magnetic resonance (CMR) stress T1 mapping using adenosine and regadenoson can differentiate ischemic, infarcted, and healthy myocardium. However, the effect of dipyridamole remains unclear.
Yuan-Ting Chang +9 more
doaj +2 more sources
Evaluation of the anticancer activity of dipyridamole and Imatinib mesylate compounds against breast cancer cell line and related biochemical and genetic changes [PDF]
Journal of Bioscience and Applied Research, 2021 Imatinib mesylate and dipyridamole were antineoplastic targeted chemotherapeutic agents, and it is here evaluating the anticancer of imatinib mesylate and dipyridamole compounds against MDA-MB231 breast cancer cell line in-vitro and the related cell ...
Rania El-Leithy +3 more
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Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways. [PDF]
Arthritis RheumatolObjective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Marco-Bonilla M +13 more
europepmc +2 more sources
Effects of dipyridamole and its use in neurology
Медицинский совет, 2021 Dipyridamole has been on the pharmaceutical market since 1959 and, as a pyrimidyl-pyrimidine compound, has a variety of mechanisms of action. The very first action of dipyridamole was its antianginal effect.
N. V. Pizova
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High Grade AV Block Associated with Dipyridamole Infusion
Case Reports in Clinical Practice, 2023 The use of dipyridamole for thallium imaging has proved very successful in demonstrating coronary arterial disease [1]. Dipyridamole causes coronary arteriolar vasodilation by increasing interstitial adenosine levels by inhibition of both adenosine ...
Mahdi Khalili +3 more
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Frontiers in Pharmacology, 2023 Introduction: Sarcopenia is defined as a loss of muscle mass and strength. ATP homeostasis is crucial during myogenesis. We determined how the purinergic system modulates myogenesis using dipyridamole (blocks adenosine taken up by the cells) and ...
Miguel Marco-Bonilla +8 more
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Effect of Dipyridamole Injected for Myocardial Perfusion Imaging on Blood Glucose Concentration; A Preliminary Study [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Dipyridamole inhibits adenosine reuptake and increases cyclic Adenosine Monophosphate (cAMP) levels in platelets, erythrocytes and endothelial cells, all of which influence blood glucose.
Amirreza Khorasanchi +7 more
doaj +1 more source
Spectroscopic and Fluorometric Determination of Cinnarizine and Dipyridamole in Pharmaceutical Tablets Using Eosin Y Dye [PDF]
مجلة التربية والعلم, 2013 Spectrophotometric and spectrofluorimetric methods were developed for the determination of cinnarizine and dipyridamole. The spectrophotometric method is based on the formation of ion pair complex between the studied drugs and eosin Y which shows ...
Zeina Al - Abdali, Elham Saleh
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