Effect of Dipyridamole Injected for Myocardial Perfusion Imaging on Blood Glucose Concentration; A Preliminary Study [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Dipyridamole inhibits adenosine reuptake and increases cyclic Adenosine Monophosphate (cAMP) levels in platelets, erythrocytes and endothelial cells, all of which influence blood glucose.
Amirreza Khorasanchi +7 more
doaj +6 more sources
Nucleoside Transport Inhibition by Dipyridamole Prevents Angiogenesis Impairment by Homocysteine and Adenosine [PDF]
Journal of Pharmacy & Pharmaceutical Sciences, 2015 Purpose: Adenosine plays an important role in the pathogenesis of homocysteine-associated vascular complications. Methods: This study examined the effects of dipyridamole, an inhibitor for nucleoside transport, on impaired angiogenic processes caused by ...
Antony Kam +4 more
doaj +2 more sources
Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury [PDF]
Advanced ScienceFerroptosis is a newly identified cell death triggered by iron‐induced lipid peroxidation. Numerous studies reveal that ferroptosis participates in multiple types of tissue injury including ischaemia–reperfusion (I/R) injury and doxorubicin (Dox)‐induced
Xiao Zhuang +22 more
doaj +2 more sources
Differentiating ischemic from healthy myocardium using cardiovascular magnetic resonance dipyridamole rest and stress T1 mapping [PDF]
Scientific ReportsCardiovascular magnetic resonance (CMR) stress T1 mapping using adenosine and regadenoson can differentiate ischemic, infarcted, and healthy myocardium. However, the effect of dipyridamole remains unclear.
Yuan-Ting Chang +9 more
doaj +2 more sources
Phosphodiesterase Inhibition and Immunotropic Activity of Dipyridamole Dynamic Derivatives [PDF]
Current Issues in Molecular BiologyIntroduction. Many pharmacological properties of dipyridamole (DIP) are associated with its ability to inhibit phosphodiesterases (PDEs). Actually, DIP has interesting properties like antiviral for influenza, SARS-2 COVID-19, and herpesviruses.
Artur Martynov +2 more
doaj +2 more sources
Impact of Coronary Microvascular Dysfunction on Left Ventricular Function After Percutaneous Coronary Intervention: Assessment With Combined Dipyridamole-Exercise Stress and Myocardial Strain/Work. [PDF]
EchocardiographyDecreased coronary flow velocity reserve (CFVR) was correlated with left ventricular (LV) dysfunction after percutaneous coronary intervention (PCI), as assessed via dipyridamole‐exercise stress echocardiography (DExE). This dysfunction was characterized by lower myocardial strain/work index and worse 1‐year Seattle Angina Questionnaire (SAQ) scores ...
Zhao W +12 more
europepmc +2 more sources
Evaluation of the anticancer activity of dipyridamole and Imatinib mesylate compounds against breast cancer cell line and related biochemical and genetic changes [PDF]
Journal of Bioscience and Applied Research, 2021 Imatinib mesylate and dipyridamole were antineoplastic targeted chemotherapeutic agents, and it is here evaluating the anticancer of imatinib mesylate and dipyridamole compounds against MDA-MB231 breast cancer cell line in-vitro and the related cell ...
Rania El-Leithy +3 more
doaj +1 more source
Effects of dipyridamole and its use in neurology
Медицинский совет, 2021 Dipyridamole has been on the pharmaceutical market since 1959 and, as a pyrimidyl-pyrimidine compound, has a variety of mechanisms of action. The very first action of dipyridamole was its antianginal effect.
N. V. Pizova
doaj +1 more source
High Grade AV Block Associated with Dipyridamole Infusion
Case Reports in Clinical Practice, 2023 The use of dipyridamole for thallium imaging has proved very successful in demonstrating coronary arterial disease [1]. Dipyridamole causes coronary arteriolar vasodilation by increasing interstitial adenosine levels by inhibition of both adenosine ...
Mahdi Khalili +3 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Introduction: Sarcopenia is defined as a loss of muscle mass and strength. ATP homeostasis is crucial during myogenesis. We determined how the purinergic system modulates myogenesis using dipyridamole (blocks adenosine taken up by the cells) and ...
Miguel Marco-Bonilla +8 more
doaj +1 more source