Frontiers in PharmacologyIntroductionMetamizole (dipyrone) is a widely used analgesic and antipyretic, but its use has been restricted in some countries due to the risk of metamizole-induced agranulocytosis (MIA).
Giovana Fernanda Santos Fidelis +10 more
doaj +1 more source
TRPA1 mediates aromatase inhibitor-evoked pain by the aromatase substrate androstenedione [PDF]
, 2016 Aromatase inhibitors (AI) induce painful musculoskeletal symptoms (AIMSS), which are dependent upon the pain transducing receptor TRPA1. However, as the AI concentrations required to engage TRPA1 in mice are higher than those found in the plasma of ...
Benemei, Silvia +15 more
core +1 more source
Evaluation of ketorolac compared to ketorolac plus dipyrone in post-operative analgesia of videolaparoscopic cholecystectomy [PDF]
Einstein (São Paulo), 2009 Objectives: To compare the analgesic effect of ketorolac with the association of ketorolac plus dipyrone after videolaparoscpic cholecystectomy and with a placebo group.
Silvia Katlauskas Muraro +2 more
doaj
Derivate nichtsteroidaler Antirheumatika als potentielle Cannabinoid- und Vanilloid-Rezeptor Liganden und Fettsäure-Derivate des Metamizols als dessen pharmakologisch aktives Prinzip [PDF]
, 2005 Die vorliegende Dissertationsarbeit beschäftigt sich zum einen mit dem möglichen Eingriff von Metaboliten der nichtsteroidalen Antirheumatika (NSAR), die strukturell mit den Endocannabinoiden bzw.
Imming, Peter (Dr.), Rogosch, Tobias
core +1 more source
Química Nova, 2005 A simple flow injection procedure was developed for determining dipyrone (1-phenyl-2,3-dimethyl-4-methylaminomethano-5-pyrazolone sodium, metamizol, analgin) in pharmaceutical formulations.
Luiz H. Marcolino-Jr. +3 more
doaj +1 more source
Pain management after outpatient surgical procedure [PDF]
, 2013 BACKGROUND AND OBJECTIVES: Adequate postoperative pain control is critical for any outpatient surgical procedure. This study aimed at evaluating analgesics and techniques used to manage pain of this type of procedure.
Munechika, Masashi +2 more
core +2 more sources
Evaluation of medication safety in the discharge medication of 509 surgical inpatients using electronic prescription support software and an extended operational interaction classification [PDF]
, 2018 Purpose: Our aim was to study drug interactions and dose adjustments in patients with renal impairment in the discharge medication of surgical inpatients and to evaluate the strengths and limitations of clinical decision support software (CDSS) for this ...
Fontana, Andrea +5 more
core
Arquivos de Neuro-Psiquiatria, 2006 INTRODUÇÃO: A enxaqueca é uma das doenças mais comuns da prática clínica. OBJETIVO: Comparar o efeito analgésico da dipirona com a metoclopramida no alívio da dor.
Sérgio Murilo Maciel Fernandes Filho +3 more
doaj +1 more source
Dual effects of Rho-kinase inhibitors on a rat model of inflammatory pain [PDF]
, 2014 BACKGROUND: Rho-kinases (ROCKs), a family of small GTP-dependent enzymes, are involved in a range of pain models, and their inhibition typically leads to antinociceptive ...
Bakhle, YS +2 more
core +3 more sources
Screening of Pharmaceuticals and Illicit Drugs in Wastewater and Surface Waters of Spain and Italy by High Resolution Mass Spectrometry using UHPLC-QTOF MS and LC-LTQ-Orbitrap MS [PDF]
, 2015 The existence of pharmaceuticals and illicit drugs (PIDs) in environmental waters has led many analytical chemists to develop screening methods for monitoring purposes.
Bade, Richard +6 more
core +2 more sources