Results 1 to 10 of about 48,247 (244)

Autoimmune manifestations and direct-acting antiviral drugs in Egyptian patients with hepatitis C virus infection: A cohort study [PDF]

Journal of International Medical Research
Objectives To investigate the clinical and serological features of autoimmunity with chronic hepatitis C virus infection before and after direct-acting antiviral therapy and assess their relation to treatment response.
Hesham I Elmakhzangy, Mai A Rabie, Dina MR Bahgat, Doaa HS Attia, Ahmed ET Elsayed, Reem Hamdy A Mohammed   +5 more
doaj   +2 more sources

Influenza in today: direct-acting antiviral therapy

Медицинский совет, 2015
Influenza is an acute infectious disease caused by influenza virus (Orthomyxoviridae family) which affects up to 15% of the world population in the cold season.
T. V. Sologub
doaj   +2 more sources

Worsening of Serum Lipid Profile after Direct Acting Antiviral Treatment [PDF]

Annals of Hepatology, 2018
Introduction. Host lipid metabolism influences viral replication and lifecycle of hepatitis C virus. Our aim was to evaluate changes in glucose and lipid metabolism of patients with chronic hepatitis C after therapy with direct acting antivirals (DAA ...
Stefano Gitto, Arrigo F.G. Cicero, Elisabetta Loggi, Marina Giovannini, Fabio Conti, Elena Grandini, Valeria Guarneri, Alessandra Scuteri, Giovanni Vitale, Carmela Cursaro, Claudio Borghi, Pietro Andreone   +11 more
doaj   +7 more sources

Management of Direct‐Acting Antiviral Failures [PDF]

Clinical Liver Disease, 2020
Answer questions and earn CME.
Maryam, Alimirah, Omar, Sadiq, Stuart C, Gordon   +2 more
openaire   +2 more sources

Direct Acting Antiviral Drugs: Pharmacokinetics and Drug-Drug Interactions

Archives of Pharmaceutical Sciences Ain Shams University, 2022
Hepatitis C (HCV) is a widespread health issue, which can lead to hepatic cirrhosis, liver failure, and liver cancer. Nearly 2% of the world's population or > 185 million people are chronically infected with HCV; the management of HCV and the rate of ...
Marina Barakat, Sara Wahdan, Azza Awad, Ebtehal El-Demerdash Zaki   +3 more
doaj   +1 more source

Efficacy and safety of direct-acting antivirals for HCV in patients with extrahepatic malignancies: real-life experience

Egyptian Liver Journal, 2022
Background Outcome of HCV treatment with direct antiviral agents in malignant patients is questionable. The aim is to assess the safety and efficacy of DAAs in treatment of chronic HCV patients who received chemotherapy for malignancies.
Mira Atef, Rasha Eletreby, Mohamed Abdallah, Rasha Salama, Wafaa Elakel, Mohamed Hassany, Wael Abdel-Razek, Yehia El Shazly, Wahid Doss, Gamal Esmat   +9 more
doaj   +1 more source

Acute reversible rhabdomyolysis during direct-acting antiviral hepatitis C virus treatment: a case report

Journal of Medical Case Reports, 2021
Introduction Treatment of hepatitis C infection has evolved dramatically since 2011. Previous conventional therapy with interferon and ribavirin used to have a low sustained virological response rate of less than 40%.
Abdulrahman Qatomah, Majidah Bukhari, Edward Cupler, Hosam Alardati, Mohammad Mawardi   +4 more
doaj   +1 more source

Clinical outcomes of patients with chronic hepatitis C after generic direct-acting antiviral treatments in Vietnam: A retrospective analysis

Asian Pacific Journal of Tropical Medicine, 2020
Objective: To evaluate the outcomes of generic direct-acting antiviral treatments for chronic hepatitis C in Vietnam. Methods: The medical records of 522 patients (median 45 years; Female, 25.3%) with chronic hepatitis C treated at a tertiary hospital in
Huong TT Vu, Azumi Ishizaki, Quynh T Nguyen, Huyen N Nguyen, Hoi T Le, Kinh V Nguyen, Hiroshi Ichimura   +6 more
doaj   +1 more source

Impact of treating chronic hepatitis C infection with direct-acting antivirals on the risk of hepatocellular carcinoma recurrence

Egyptian Liver Journal, 2020
Background The impact of direct-acting antivirals (DAAs) remains a debate, whether they accelerate the recurrence rate of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC) after curative therapy.
Nevine Ibrahim Musa, Inas Elkhedr Mohamed, Ahmed Samir Abohalima   +2 more
doaj   +1 more source

Direct-acting antiviral therapy of chronic hepatitis C improves liver fibrosis, assessed by histological examination and laboratory markers

Journal of the Formosan Medical Association, 2021
Background/Purpose: Direct-acting antiviral agents achieve sustained virological response in most chronic hepatitis C patients. However, histological responses are not consistent among all patients.
Chun-Han Cheng, Chia-Ying Chu, Huan-Lin Chen, I-Tsung Lin, Chia-Hsien Wu, Yuan-Kai Lee, Ping-Jen Hu, Ming-Jong Bair   +7 more
doaj   +1 more source